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The map label for this gene is atpB

Identifier: 109947723

GI number: 109947723

Start: 1033225

End: 1033905

Strand: Reverse

Name: atpB

Synonym: Hac_1196

Alternate gene names: 109947723

Gene position: 1033905-1033225 (Counterclockwise)

Preceding gene: 109947724

Following gene: 109947722

Centisome position: 66.53

GC content: 39.21

Gene sequence:

>681_bases
ATGGAACACAGAGTATTTACTGTTGCTAATTTTTTTAGCTCTAATCATGATTTTATCACCGGTTTTTTCGTTGTTTTGAC
AGCGGTTTTGATGTTTTTAATTTCTCTTGGTGCATCGCGTAAAATGCAGATGGTACCTATGGGTTTGCAAAATGTGTATG
AGAGTATTATTAGTGCCATTTTAAGCGTGGCTAAGGATATTATAGGCGAAGAATTGGCCCGCAAATACTTCCCACTAGCC
GGCACGATCGCTTTGTATGTCTTTTTTTCTAACATGATAGGCATCATTCCTAGTTTTGAATCCCCCACGGCTAGTTGGAG
TTTTACGCTAGTTTTAGCGCTGATTGTGTTTTTTTATTACCACTTTGAAGGCATTAGAGTGCAGGGTTTTTTTAAGTATT
TCGCCCATTTTGCAGGTCCCGTGAAGTGGCTCGCACCTTTCATGTTCCCTATTGAAATTATCTCGCATTTTTCTAGGATT
GTGTCTTTATCGTTTCGTTTGTTTGGGAATATCAAGGGCGATGACATGTTTTTACTCATCATGCTCTTATTAGTGCCTTG
GGTTATTCCTGTAGCACCCTTTATGGTCTTGTTTTTCATGGGGATTTTGCAAGCTTTTGTTTTTATGATCCTTACTTATG
TGTATTTGGCAGGGGCTGTTTTAACCGATGAGGGGCATTGA

Upstream 100 bases:

>100_bases
AATCATTAAAAAACTCGTTAAAAAGCTTGGTTTAATGAGTTTTTAAAACTTAATTGCTACAATGAAGAAAATTTTCAATA
AGGCTTAGAGAAACTTTTTC

Downstream 100 bases:

>100_bases
TTAAAACAAAGTTAAGCAATCATTAGATAAAATTTGTTATGCTTTCGTGTCGGATGTGTTGGGTTTTTAAGAGTGTTACT
TTTTGATAACTTTTTCATAT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEHRVFTVANFFSSNHDFITGFFVVLTAVLMFLISLGASRKMQMVPMGLQNVYESIISAILSVAKDIIGEELARKYFPLA
GTIALYVFFSNMIGIIPSFESPTASWSFTLVLALIVFFYYHFEGIRVQGFFKYFAHFAGPVKWLAPFMFPIEIISHFSRI
VSLSFRLFGNIKGDDMFLLIMLLLVPWVIPVAPFMVLFFMGILQAFVFMILTYVYLAGAVLTDEGH

Sequences:

>Translated_226_residues
MEHRVFTVANFFSSNHDFITGFFVVLTAVLMFLISLGASRKMQMVPMGLQNVYESIISAILSVAKDIIGEELARKYFPLA
GTIALYVFFSNMIGIIPSFESPTASWSFTLVLALIVFFYYHFEGIRVQGFFKYFAHFAGPVKWLAPFMFPIEIISHFSRI
VSLSFRLFGNIKGDDMFLLIMLLLVPWVIPVAPFMVLFFMGILQAFVFMILTYVYLAGAVLTDEGH
>Mature_226_residues
MEHRVFTVANFFSSNHDFITGFFVVLTAVLMFLISLGASRKMQMVPMGLQNVYESIISAILSVAKDIIGEELARKYFPLA
GTIALYVFFSNMIGIIPSFESPTASWSFTLVLALIVFFYYHFEGIRVQGFFKYFAHFAGPVKWLAPFMFPIEIISHFSRI
VSLSFRLFGNIKGDDMFLLIMLLLVPWVIPVAPFMVLFFMGILQAFVFMILTYVYLAGAVLTDEGH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=212, Percent_Identity=29.2452830188679, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6226527, Length=185, Percent_Identity=29.7297297297297, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_HELAH (Q17WM4)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664951.1
- ProteinModelPortal:   Q17WM4
- SMR:   Q17WM4
- STRING:   Q17WM4
- GeneID:   4177103
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_1196
- NMPDR:   fig|382638.8.peg.1161
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   YIFTILT
- PhylomeDB:   Q17WM4
- ProtClustDB:   PRK05815
- BioCyc:   HACI382638:HAC_1196-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 25673; Mature: 25673

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13986e74)-; HASH(0x1272dc7c)-; HASH(0x132bcb7c)-; HASH(0x13c4e9b0)-; HASH(0x13df7320)-; HASH(0x117a4edc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHRVFTVANFFSSNHDFITGFFVVLTAVLMFLISLGASRKMQMVPMGLQNVYESIISAI
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHH
LSVAKDIIGEELARKYFPLAGTIALYVFFSNMIGIIPSFESPTASWSFTLVLALIVFFYY
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
HFEGIRVQGFFKYFAHFAGPVKWLAPFMFPIEIISHFSRIVSLSFRLFGNIKGDDMFLLI
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MLLLVPWVIPVAPFMVLFFMGILQAFVFMILTYVYLAGAVLTDEGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MEHRVFTVANFFSSNHDFITGFFVVLTAVLMFLISLGASRKMQMVPMGLQNVYESIISAI
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHH
LSVAKDIIGEELARKYFPLAGTIALYVFFSNMIGIIPSFESPTASWSFTLVLALIVFFYY
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
HFEGIRVQGFFKYFAHFAGPVKWLAPFMFPIEIISHFSRIVSLSFRLFGNIKGDDMFLLI
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MLLLVPWVIPVAPFMVLFFMGILQAFVFMILTYVYLAGAVLTDEGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA