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The map label for this gene is atoB [H]

Identifier: 109947502

GI number: 109947502

Start: 838048

End: 839223

Strand: Reverse

Name: atoB [H]

Synonym: Hac_0958

Alternate gene names: 109947502

Gene position: 839223-838048 (Counterclockwise)

Preceding gene: 109947509

Following gene: 109947501

Centisome position: 54.01

GC content: 43.79

Gene sequence:

>1176_bases
ATGAATGAAGTGGTTGTAGTAGCGGCAAAGCGTAGCGCTGTAGGGAGTTTTTTAGGCTCTTTGAAAAATGTGAGCGTTAG
GCAAATGGGTGTTAGCGTGCTTAAAGACGCTTTAAAGGCGAGCGGACTTGATCCTAACGATGTAGATTCAGTTATTTTAG
GCAATGTCTTATCCGCTGGTTTGGGTCAAAATATCGCTAGGCAAATCCAACTGGATGCAAGCATACCTAATGACAGGCAT
GCTTTTAGCGTTAATATGGTTTGTGGGTCGTCCTTGAAAGCCATTCAGTTAGCACATGATAGCATCATGCTTGGGCGCGA
TGAAGTGGTGGTGTGCGGTGGCGTGGAGAACATGAGTGCAGCACCTTATTTGTCGTTTGACATGCGAGAGGGAAAAAGAA
TGGGGAATGCGAACATGATAGATTCTATGGTTTATGACGGACTATGGGATGCGTTCAATGATTACCACATGGGGATCACC
GCAGACAATATCGCTAAAGCATACCACATAAGCCGAGAAGAACAAGACGCATTTGCACTCCAATCGCAACTCAAAGCAAG
AGTTGCTATCAATGCAGGGAAATTCCAAGAAGAAATCACTCCCATTGAAATAGTAAATAAAAAAGGCACGATTGTTTTCA
AAGAAGACGAATACCCTAGAGACACGACGCTAGAATCCCTTGCAAAGCTCAAACCTGCCTTTAAAAAAGACGGATCGGTA
ACGGCAGGGAATTCATCAGGAATCAATGATGGTGCTAGCGTAGTGATTTTATGCAGTGCTAAAAAAGTGCAAAAGCTAGG
GTTAAAAGTAATGGCGGTTATCAAGGGGTTTGGTTTGGGCGGTTGCAGTCCGGACATAATGGGTATATGCCCAAGCATTG
CGATTAAAAACAACCTTAAAAATGTCAAAATGCATCTTGACGACATCAATCTTTTTGAACTCAATGAAGCCTTTGCCGCT
CAAAGTATAGCCGTGTTAAAAGAGCTTGAACTCAACCCCAATATCGTGAATGTGAATGGCGGTGCAATAGCGATTGGCCA
TCCTATTGGGGCGAGCGGTGCTAGGATATTGGTTACCCTTTTGCATGAAATGAAGCGAAGTGGGCATGGTATTGGTTGTG
CATCATTGTGCGTGGGTGGTGGGCAAGGAATATCAGTGATTGTTGAACAAAAATAA

Upstream 100 bases:

>100_bases
TTCAATACAAGACAAAATCTCAAACAAAATAAAATAGGTTAGGGCGCTAATTATCTAAAAGTGATACTATGACTGAGTAG
ATTAACTTAAAGGCAAAGAT

Downstream 100 bases:

>100_bases
GGAGAATGAGATGAATAAGGTTATAACGGATTTAGACAAAGGATTGAATGGGTTAAAAGATGGGGATACTATTTTAGTGG
GTGGTTTTGGGTTGTGCGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNEVVVVAAKRSAVGSFLGSLKNVSVRQMGVSVLKDALKASGLDPNDVDSVILGNVLSAGLGQNIARQIQLDASIPNDRH
AFSVNMVCGSSLKAIQLAHDSIMLGRDEVVVCGGVENMSAAPYLSFDMREGKRMGNANMIDSMVYDGLWDAFNDYHMGIT
ADNIAKAYHISREEQDAFALQSQLKARVAINAGKFQEEITPIEIVNKKGTIVFKEDEYPRDTTLESLAKLKPAFKKDGSV
TAGNSSGINDGASVVILCSAKKVQKLGLKVMAVIKGFGLGGCSPDIMGICPSIAIKNNLKNVKMHLDDINLFELNEAFAA
QSIAVLKELELNPNIVNVNGGAIAIGHPIGASGARILVTLLHEMKRSGHGIGCASLCVGGGQGISVIVEQK

Sequences:

>Translated_391_residues
MNEVVVVAAKRSAVGSFLGSLKNVSVRQMGVSVLKDALKASGLDPNDVDSVILGNVLSAGLGQNIARQIQLDASIPNDRH
AFSVNMVCGSSLKAIQLAHDSIMLGRDEVVVCGGVENMSAAPYLSFDMREGKRMGNANMIDSMVYDGLWDAFNDYHMGIT
ADNIAKAYHISREEQDAFALQSQLKARVAINAGKFQEEITPIEIVNKKGTIVFKEDEYPRDTTLESLAKLKPAFKKDGSV
TAGNSSGINDGASVVILCSAKKVQKLGLKVMAVIKGFGLGGCSPDIMGICPSIAIKNNLKNVKMHLDDINLFELNEAFAA
QSIAVLKELELNPNIVNVNGGAIAIGHPIGASGARILVTLLHEMKRSGHGIGCASLCVGGGQGISVIVEQK
>Mature_391_residues
MNEVVVVAAKRSAVGSFLGSLKNVSVRQMGVSVLKDALKASGLDPNDVDSVILGNVLSAGLGQNIARQIQLDASIPNDRH
AFSVNMVCGSSLKAIQLAHDSIMLGRDEVVVCGGVENMSAAPYLSFDMREGKRMGNANMIDSMVYDGLWDAFNDYHMGIT
ADNIAKAYHISREEQDAFALQSQLKARVAINAGKFQEEITPIEIVNKKGTIVFKEDEYPRDTTLESLAKLKPAFKKDGSV
TAGNSSGINDGASVVILCSAKKVQKLGLKVMAVIKGFGLGGCSPDIMGICPSIAIKNNLKNVKMHLDDINLFELNEAFAA
QSIAVLKELELNPNIVNVNGGAIAIGHPIGASGARILVTLLHEMKRSGHGIGCASLCVGGGQGISVIVEQK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=393, Percent_Identity=48.3460559796438, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI167614485, Length=392, Percent_Identity=45.1530612244898, Blast_Score=324, Evalue=8e-89,
Organism=Homo sapiens, GI4557237, Length=394, Percent_Identity=39.8477157360406, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI4501853, Length=395, Percent_Identity=39.4936708860759, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI4504327, Length=424, Percent_Identity=29.9528301886792, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI194353979, Length=389, Percent_Identity=28.0205655526992, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI87082165, Length=391, Percent_Identity=49.616368286445, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1788554, Length=392, Percent_Identity=49.4897959183673, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1787663, Length=409, Percent_Identity=36.6748166259169, Blast_Score=244, Evalue=8e-66,
Organism=Escherichia coli, GI48994986, Length=401, Percent_Identity=38.6533665835411, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1788683, Length=412, Percent_Identity=28.3980582524272, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI133906874, Length=388, Percent_Identity=43.0412371134021, Blast_Score=317, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17535921, Length=391, Percent_Identity=36.3171355498721, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI25147385, Length=386, Percent_Identity=36.5284974093264, Blast_Score=245, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17535917, Length=393, Percent_Identity=29.2620865139949, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17551802, Length=400, Percent_Identity=29.75, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6325229, Length=394, Percent_Identity=42.1319796954315, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6322031, Length=396, Percent_Identity=36.8686868686869, Blast_Score=210, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24655093, Length=391, Percent_Identity=48.0818414322251, Blast_Score=380, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24640423, Length=390, Percent_Identity=41.7948717948718, Blast_Score=307, Evalue=7e-84,
Organism=Drosophila melanogaster, GI17648125, Length=389, Percent_Identity=42.9305912596401, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI17137578, Length=390, Percent_Identity=32.3076923076923, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41417; Mature: 41417

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVVVVAAKRSAVGSFLGSLKNVSVRQMGVSVLKDALKASGLDPNDVDSVILGNVLSAG
CCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LGQNIARQIQLDASIPNDRHAFSVNMVCGSSLKAIQLAHDSIMLGRDEVVVCGGVENMSA
HCHHHHHEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCEEECCCCEEEECCCCCCCC
APYLSFDMREGKRMGNANMIDSMVYDGLWDAFNDYHMGITADNIAKAYHISREEQDAFAL
CCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHH
QSQLKARVAINAGKFQEEITPIEIVNKKGTIVFKEDEYPRDTTLESLAKLKPAFKKDGSV
HHHHHEEEEEECCCHHHHCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHCHHHHCCCCE
TAGNSSGINDGASVVILCSAKKVQKLGLKVMAVIKGFGLGGCSPDIMGICPSIAIKNNLK
ECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHCCCC
NVKMHLDDINLFELNEAFAAQSIAVLKELELNPNIVNVNGGAIAIGHPIGASGARILVTL
EEEEEECCCCEEECHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHHHHH
LHEMKRSGHGIGCASLCVGGGQGISVIVEQK
HHHHHHCCCCCCHHHHHCCCCCCEEEEEECC
>Mature Secondary Structure
MNEVVVVAAKRSAVGSFLGSLKNVSVRQMGVSVLKDALKASGLDPNDVDSVILGNVLSAG
CCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LGQNIARQIQLDASIPNDRHAFSVNMVCGSSLKAIQLAHDSIMLGRDEVVVCGGVENMSA
HCHHHHHEEEEECCCCCCCCEEEEEEEECCCCCEEEEECCCEEECCCCEEEECCCCCCCC
APYLSFDMREGKRMGNANMIDSMVYDGLWDAFNDYHMGITADNIAKAYHISREEQDAFAL
CCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHH
QSQLKARVAINAGKFQEEITPIEIVNKKGTIVFKEDEYPRDTTLESLAKLKPAFKKDGSV
HHHHHEEEEEECCCHHHHCCCEEEECCCCCEEEECCCCCCCHHHHHHHHHCHHHHCCCCE
TAGNSSGINDGASVVILCSAKKVQKLGLKVMAVIKGFGLGGCSPDIMGICPSIAIKNNLK
ECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHCCCC
NVKMHLDDINLFELNEAFAAQSIAVLKELELNPNIVNVNGGAIAIGHPIGASGARILVTL
EEEEEECCCCEEECHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHHHHH
LHEMKRSGHGIGCASLCVGGGQGISVIVEQK
HHHHHHCCCCCCHHHHHCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7867955; 11075929; 11466286; 1685080 [H]