Click here to switch to the map view.

The map label for this gene is scoA [H]

Identifier: 109947501

GI number: 109947501

Start: 837339

End: 838037

Strand: Reverse

Name: scoA [H]

Synonym: Hac_0957

Alternate gene names: 109947501

Gene position: 838037-837339 (Counterclockwise)

Preceding gene: 109947502

Following gene: 109947500

Centisome position: 53.93

GC content: 40.2

Gene sequence:

>699_bases
ATGAATAAGGTTATAACGGATTTAGACAAAGGATTGAATGGGTTAAAAGATGGGGATACTATTTTAGTGGGTGGTTTTGG
GTTGTGCGGGATACCCGAATACGCCATTGATTATATCTATAAAAAGGGCATCAAGGATTTGATTGTCGTGAGCAATAATT
GCGGTGTTGATGACTTTGGGTTGGGTATTCTTTTAGAAAAAAAACAGATTAAAAAAATTATCGCTTCGTATGTGGGGGAG
AATAAGATTTTTGAATCACAGTTATTGAATGGGGAAATTGAAGTCGTTTTGACTCCGCAAGGCACGCTCGCTGAAAATCT
GCGTGCTGGAGGGGCTGGGATACCCGCTTACTACACCCCAACAGGTGTTGGGACTTTGATCGCTCAAGGCAAGGAATCAA
GGGAATTTAATGGCAAAGAGTATATTTTAGAAAGAGCGATAACAGGCGATTATGGGCTTATTAAAGCTTATAAAGGCGAT
ACTCTTGGGAATTTGGTGTTTAGAAAAACGGCTAGAAATTTCAACCCCTTGTGTGCGATGGCGTCAAAAATATGTATCGC
TGAAGTGGAAGAAATCGTTCCGGCTGGGGAATTAGACCCAGATGAAATACACTTGCCAGGGATTTATGTGCAACACATTT
ATAAGGGCGAGAAATTTGAAAAACGGATAGAAAAAATCACAACAAGGAGCACAAAATGA

Upstream 100 bases:

>100_bases
GAAATGAAGCGAAGTGGGCATGGTATTGGTTGTGCATCATTGTGCGTGGGTGGTGGGCAAGGAATATCAGTGATTGTTGA
ACAAAAATAAGGAGAATGAG

Downstream 100 bases:

>100_bases
GAGAGGCTATCATTAAAAGAGCGGCGAAAGAATTGAAAGAAGGCATGTATGTGAATTTAGGGATAGGTTTGCCCACGCTT
GTAGCCAATGAAGTGAGTGG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKVITDLDKGLNGLKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQLLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKGD
TLGNLVFRKTARNFNPLCAMASKICIAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSTK

Sequences:

>Translated_232_residues
MNKVITDLDKGLNGLKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQLLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKGD
TLGNLVFRKTARNFNPLCAMASKICIAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSTK
>Mature_232_residues
MNKVITDLDKGLNGLKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQLLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKGD
TLGNLVFRKTARNFNPLCAMASKICIAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSTK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=55.4655870445344, Blast_Score=278, Evalue=3e-75,
Organism=Homo sapiens, GI11545841, Length=232, Percent_Identity=53.0172413793103, Blast_Score=245, Evalue=2e-65,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=42.6470588235294, Blast_Score=192, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=50.4098360655738, Blast_Score=239, Evalue=6e-64,
Organism=Drosophila melanogaster, GI24655794, Length=237, Percent_Identity=53.5864978902954, Blast_Score=254, Evalue=4e-68,
Organism=Drosophila melanogaster, GI21358325, Length=237, Percent_Identity=53.5864978902954, Blast_Score=254, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25363; Mature: 25363

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVITDLDKGLNGLKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFG
CCCHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LGILLEKKQIKKIIASYVGENKIFESQLLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTP
CEEEECHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEECC
TGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKGDTLGNLVFRKTARNFNPLCAM
CCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHH
ASKICIAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSTK
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVITDLDKGLNGLKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFG
CCCHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LGILLEKKQIKKIIASYVGENKIFESQLLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTP
CEEEECHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEECC
TGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKGDTLGNLVFRKTARNFNPLCAM
CCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCCHHHHH
ASKICIAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSTK
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]