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The map label for this gene is hyuB [H]

Identifier: 109947496

GI number: 109947496

Start: 829508

End: 831805

Strand: Reverse

Name: hyuB [H]

Synonym: Hac_0950

Alternate gene names: 109947496

Gene position: 831805-829508 (Counterclockwise)

Preceding gene: 109947497

Following gene: 109947495

Centisome position: 53.53

GC content: 42.56

Gene sequence:

>2298_bases
ATGGCAAATTTATTGAAAAACGGCAAAACTTTAAAACAAGCTAGAGATGAAATCCTAGCTAGGACAGAAAAAACAGGTTA
TTACAATGGGCTTGAAAAATTAGAGTTCAAAGAAAGCGATCCGATCGGTTATGAAAAAATGTTCTCTAAATTGAGAGGCG
GTATTGTGCATGCCAGAGAAACAGCCAAAAGGATTGCTGCAAGCCCTATTGTTGAGCAAGAGGGGGAATTGTGCTTCACG
CTTTATAACGCTTTGGGCGATAGCGTGCTGACTTCTACGGGTATCATTATCCATGTGGGCACTATGGGATCGGCTATCAA
ATACATGGTAGAGAATGGTTGGGAAGATAACCCTGGCATCAATGATAAGGATATTTTCACCAATAATGACTGTGCGATTG
GGAATGTGCATCCATGCGATATTATGACTCTTGTGCCTATCTTTCACGATGAAAAATTGATTGGGTGGGTAGGCGGTGTT
ACGCATGTGATTGATACTGGGTCGGTTACTCCAGGATCGATGAGCACTGGACAGGTTCAAAGATTTGGGGATGGATACAT
GATCACTTGCCGTAAGACAGGGGCGAATGATGAGAGTTTTAAAGATTGGTTGCATGAATCCCAAAGATCAGTAAGAACGC
CTAAATATTGGATTTTGGATGAAAGGACTAGGATTGCAGGATGCCACATGATTAGGGATCTTGTGATGGAAGTGATTAAA
GAAGATGGCATCGATTCTTACATGCGATTCATTGATGAGGTGATTGAAGAGGGAAGAAGAGGTCTTATCTCTAGGATCAA
GTCCATGACCATACCGGGCAAGTATAGAAAGGTAGCGTTTGTGGATGTGCCTTATGCACATAAGGATATTGGCGTGTGCT
CTGAGTTTGCTAAACTAGACACAATCATGCATTCTCCGGTAGAAATCACTATCAATAAGGACGCTACATGGAAATTAGAC
TTTGATGGTGCATCTAGGTGGGGGTGGCATTCCTTTAATTGCAACCAAGTGTCCTTTACTAGCGGTATTTGGGTGATGAT
GACTCAAACATTGATCCCCACTTCTCGCATCAATGATGGTGCTTATTTTGCGACTCAATTCAGACTCAAAAAAGGGACTT
GGATGAATCCAGACGATAGGCGCACTGGGCATGCTTACGCATGGCATTTCTTGGTATCCGGTTGGAGTGCTTTGTGGAGA
GGCTTGTCTCAAGCGTATTATAGCCGAGGGTATTTAGAGGAGGTCAATTCTGGAAACGCCAACACTTCTAATTGGTTGCA
AGGCGGTGGTATCAACCAAGATGGAGAGATCCATGCGGTGAATAGCTTTGAGACGAGCTCTTGTGGGAGTGGTGCTTGTG
CGATCAAAGATGGCTTGAACCACGCAGCAGCTATTTGGAACCCAGAAGGTGATATGGGTGATATTGAAATCTGGGAAATG
GCAGAACCTCTTCTTTATTTAGGTAGGAATGTCAAGGCCAATACCGGTGGGTATGGGAAATATCGAGGCGGTAATGGGTT
TGAAACCTTAAGAATGGTGTGGGGTGCACATGATTGGACCATGTTTTTTATGGGTAATGGCTACATGAATAGTGATTGGG
GTATGATGGGGGGTTATCCAGCGGCTAGTGGTTATAGGTTTGAAGCGCACAACACTGATTTGAAAAATAGGATTAAAAAT
AACGACAGCTTGCCTTTGGGTGGTGATTTTAACCCAATTGATTGCGATTATGAAAAGCATATCTCTCGTGCCTCTCAAGT
CAAAAGGGATAAGCAATGCATCACCACAGAAAATTGCTTTGATAATTATGACTTGTATTTGAACTACATCAAAGGCGGTC
CTGGATTTGGCGATCCGATTGAAAGGGATTTGAGTGCCATTTTAGAAGACCTAAACAGCAAACAGCTATTGCCAGAATAC
GCCTACAAGGTTTATGGTGCGGTTGTGAGTCAAAATAAAGACGGCGTTTGGGTAGGGGATGAGGCCAAAACTGAAGCTAG
AAGAAAAGAAATTCTTGAAACTAGGAAATCTAGATCCATACCTGTAAAACAATGGATGGAGCAAGAAAGAAGCGCTATCC
TTAAAAAAGAGGCTTCCAAACAGGTTAAACACATGTATGCGACTAGCTTTGATCTTTCGCCGAAGTTTTTGAGCGACTTT
AAAAAATTTTGGAACTTGCCGGATAGTTGGACTATGCAAGAAGATGAGCTTGGCGTATTCACTTATGGTTCTAAATACAG
AATGGATTTGAGCAAATTGCCTGATGTGCACACGGTTGTGTTGGTTGATGAAAAATAA

Upstream 100 bases:

>100_bases
ATGCGACCACATTCGTGGTGCCTAAAGGCTTTGCGACAAAGTTAGACAAACACAGATTGTTCCACTTGAAAGAAGTTAAA
TAATAGTAAAGGAGTTCTAA

Downstream 100 bases:

>100_bases
GTTTTTAAAAAAATAGAGGAGAATGGTTATGTCAAAATACACACAAGAACAAATCAAAAATTTAGTAGAGGGGAGCTTGG
ATTGGAGCACGATCTTAAAA

Product: N-methylhydantoinase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 764

Protein sequence:

>765_residues
MANLLKNGKTLKQARDEILARTEKTGYYNGLEKLEFKESDPIGYEKMFSKLRGGIVHARETAKRIAASPIVEQEGELCFT
LYNALGDSVLTSTGIIIHVGTMGSAIKYMVENGWEDNPGINDKDIFTNNDCAIGNVHPCDIMTLVPIFHDEKLIGWVGGV
THVIDTGSVTPGSMSTGQVQRFGDGYMITCRKTGANDESFKDWLHESQRSVRTPKYWILDERTRIAGCHMIRDLVMEVIK
EDGIDSYMRFIDEVIEEGRRGLISRIKSMTIPGKYRKVAFVDVPYAHKDIGVCSEFAKLDTIMHSPVEITINKDATWKLD
FDGASRWGWHSFNCNQVSFTSGIWVMMTQTLIPTSRINDGAYFATQFRLKKGTWMNPDDRRTGHAYAWHFLVSGWSALWR
GLSQAYYSRGYLEEVNSGNANTSNWLQGGGINQDGEIHAVNSFETSSCGSGACAIKDGLNHAAAIWNPEGDMGDIEIWEM
AEPLLYLGRNVKANTGGYGKYRGGNGFETLRMVWGAHDWTMFFMGNGYMNSDWGMMGGYPAASGYRFEAHNTDLKNRIKN
NDSLPLGGDFNPIDCDYEKHISRASQVKRDKQCITTENCFDNYDLYLNYIKGGPGFGDPIERDLSAILEDLNSKQLLPEY
AYKVYGAVVSQNKDGVWVGDEAKTEARRKEILETRKSRSIPVKQWMEQERSAILKKEASKQVKHMYATSFDLSPKFLSDF
KKFWNLPDSWTMQEDELGVFTYGSKYRMDLSKLPDVHTVVLVDEK

Sequences:

>Translated_765_residues
MANLLKNGKTLKQARDEILARTEKTGYYNGLEKLEFKESDPIGYEKMFSKLRGGIVHARETAKRIAASPIVEQEGELCFT
LYNALGDSVLTSTGIIIHVGTMGSAIKYMVENGWEDNPGINDKDIFTNNDCAIGNVHPCDIMTLVPIFHDEKLIGWVGGV
THVIDTGSVTPGSMSTGQVQRFGDGYMITCRKTGANDESFKDWLHESQRSVRTPKYWILDERTRIAGCHMIRDLVMEVIK
EDGIDSYMRFIDEVIEEGRRGLISRIKSMTIPGKYRKVAFVDVPYAHKDIGVCSEFAKLDTIMHSPVEITINKDATWKLD
FDGASRWGWHSFNCNQVSFTSGIWVMMTQTLIPTSRINDGAYFATQFRLKKGTWMNPDDRRTGHAYAWHFLVSGWSALWR
GLSQAYYSRGYLEEVNSGNANTSNWLQGGGINQDGEIHAVNSFETSSCGSGACAIKDGLNHAAAIWNPEGDMGDIEIWEM
AEPLLYLGRNVKANTGGYGKYRGGNGFETLRMVWGAHDWTMFFMGNGYMNSDWGMMGGYPAASGYRFEAHNTDLKNRIKN
NDSLPLGGDFNPIDCDYEKHISRASQVKRDKQCITTENCFDNYDLYLNYIKGGPGFGDPIERDLSAILEDLNSKQLLPEY
AYKVYGAVVSQNKDGVWVGDEAKTEARRKEILETRKSRSIPVKQWMEQERSAILKKEASKQVKHMYATSFDLSPKFLSDF
KKFWNLPDSWTMQEDELGVFTYGSKYRMDLSKLPDVHTVVLVDEK
>Mature_764_residues
ANLLKNGKTLKQARDEILARTEKTGYYNGLEKLEFKESDPIGYEKMFSKLRGGIVHARETAKRIAASPIVEQEGELCFTL
YNALGDSVLTSTGIIIHVGTMGSAIKYMVENGWEDNPGINDKDIFTNNDCAIGNVHPCDIMTLVPIFHDEKLIGWVGGVT
HVIDTGSVTPGSMSTGQVQRFGDGYMITCRKTGANDESFKDWLHESQRSVRTPKYWILDERTRIAGCHMIRDLVMEVIKE
DGIDSYMRFIDEVIEEGRRGLISRIKSMTIPGKYRKVAFVDVPYAHKDIGVCSEFAKLDTIMHSPVEITINKDATWKLDF
DGASRWGWHSFNCNQVSFTSGIWVMMTQTLIPTSRINDGAYFATQFRLKKGTWMNPDDRRTGHAYAWHFLVSGWSALWRG
LSQAYYSRGYLEEVNSGNANTSNWLQGGGINQDGEIHAVNSFETSSCGSGACAIKDGLNHAAAIWNPEGDMGDIEIWEMA
EPLLYLGRNVKANTGGYGKYRGGNGFETLRMVWGAHDWTMFFMGNGYMNSDWGMMGGYPAASGYRFEAHNTDLKNRIKNN
DSLPLGGDFNPIDCDYEKHISRASQVKRDKQCITTENCFDNYDLYLNYIKGGPGFGDPIERDLSAILEDLNSKQLLPEYA
YKVYGAVVSQNKDGVWVGDEAKTEARRKEILETRKSRSIPVKQWMEQERSAILKKEASKQVKHMYATSFDLSPKFLSDFK
KFWNLPDSWTMQEDELGVFTYGSKYRMDLSKLPDVHTVVLVDEK

Specific function: Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide [H]

COG id: COG0146

COG function: function code EQ; N-methylhydantoinase B/acetone carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003692 [H]

Pfam domain/function: PF02538 Hydantoinase_B [H]

EC number: =6.4.1.6 [H]

Molecular weight: Translated: 86372; Mature: 86240

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLLKNGKTLKQARDEILARTEKTGYYNGLEKLEFKESDPIGYEKMFSKLRGGIVHARE
CCCCHHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCEEHHHH
TAKRIAASPIVEQEGELCFTLYNALGDSVLTSTGIIIHVGTMGSAIKYMVENGWEDNPGI
HHHHHHHCCCHHCCCCCHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCCC
NDKDIFTNNDCAIGNVHPCDIMTLVPIFHDEKLIGWVGGVTHVIDTGSVTPGSMSTGQVQ
CCCCCEECCCCCCCCCCCCCHHEEEHHHCCCHHHHHHCCHHHHEECCCCCCCCCCCCCHH
RFGDGYMITCRKTGANDESFKDWLHESQRSVRTPKYWILDERTRIAGCHMIRDLVMEVIK
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
EDGIDSYMRFIDEVIEEGRRGLISRIKSMTIPGKYRKVAFVDVPYAHKDIGVCSEFAKLD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
TIMHSPVEITINKDATWKLDFDGASRWGWHSFNCNQVSFTSGIWVMMTQTLIPTSRINDG
HHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEECCCEEEEHHHHHCCCCCCCCC
AYFATQFRLKKGTWMNPDDRRTGHAYAWHFLVSGWSALWRGLSQAYYSRGYLEEVNSGNA
EEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC
NTSNWLQGGGINQDGEIHAVNSFETSSCGSGACAIKDGLNHAAAIWNPEGDMGDIEIWEM
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHHHCCCCCEEEECCCCCCCCEEHHHH
AEPLLYLGRNVKANTGGYGKYRGGNGFETLRMVWGAHDWTMFFMGNGYMNSDWGMMGGYP
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCEECCCCCCCCCCC
AASGYRFEAHNTDLKNRIKNNDSLPLGGDFNPIDCDYEKHISRASQVKRDKQCITTENCF
CCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCC
DNYDLYLNYIKGGPGFGDPIERDLSAILEDLNSKQLLPEYAYKVYGAVVSQNKDGVWVGD
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEECC
EAKTEARRKEILETRKSRSIPVKQWMEQERSAILKKEASKQVKHMYATSFDLSPKFLSDF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KKFWNLPDSWTMQEDELGVFTYGSKYRMDLSKLPDVHTVVLVDEK
HHHCCCCCCCCCCCCCCEEEECCCCEEECHHHCCCEEEEEEEECC
>Mature Secondary Structure 
ANLLKNGKTLKQARDEILARTEKTGYYNGLEKLEFKESDPIGYEKMFSKLRGGIVHARE
CCCHHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHCCEEHHHH
TAKRIAASPIVEQEGELCFTLYNALGDSVLTSTGIIIHVGTMGSAIKYMVENGWEDNPGI
HHHHHHHCCCHHCCCCCHHHHHHHHCCHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCCC
NDKDIFTNNDCAIGNVHPCDIMTLVPIFHDEKLIGWVGGVTHVIDTGSVTPGSMSTGQVQ
CCCCCEECCCCCCCCCCCCCHHEEEHHHCCCHHHHHHCCHHHHEECCCCCCCCCCCCCHH
RFGDGYMITCRKTGANDESFKDWLHESQRSVRTPKYWILDERTRIAGCHMIRDLVMEVIK
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
EDGIDSYMRFIDEVIEEGRRGLISRIKSMTIPGKYRKVAFVDVPYAHKDIGVCSEFAKLD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
TIMHSPVEITINKDATWKLDFDGASRWGWHSFNCNQVSFTSGIWVMMTQTLIPTSRINDG
HHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCEEEECCCEEEEHHHHHCCCCCCCCC
AYFATQFRLKKGTWMNPDDRRTGHAYAWHFLVSGWSALWRGLSQAYYSRGYLEEVNSGNA
EEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC
NTSNWLQGGGINQDGEIHAVNSFETSSCGSGACAIKDGLNHAAAIWNPEGDMGDIEIWEM
CCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEHHHCCCCCEEEECCCCCCCCEEHHHH
AEPLLYLGRNVKANTGGYGKYRGGNGFETLRMVWGAHDWTMFFMGNGYMNSDWGMMGGYP
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCEECCCCCCCCCCC
AASGYRFEAHNTDLKNRIKNNDSLPLGGDFNPIDCDYEKHISRASQVKRDKQCITTENCF
CCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCC
DNYDLYLNYIKGGPGFGDPIERDLSAILEDLNSKQLLPEYAYKVYGAVVSQNKDGVWVGD
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEECC
EAKTEARRKEILETRKSRSIPVKQWMEQERSAILKKEASKQVKHMYATSFDLSPKFLSDF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
KKFWNLPDSWTMQEDELGVFTYGSKYRMDLSKLPDVHTVVLVDEK
HHHCCCCCCCCCCCCCCEEEECCCCEEECHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12003937 [H]