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The map label for this gene is rodA [H]

Identifier: 109947251

GI number: 109947251

Start: 591969

End: 593114

Strand: Direct

Name: rodA [H]

Synonym: Hac_0676

Alternate gene names: 109947251

Gene position: 591969-593114 (Clockwise)

Preceding gene: 109947250

Following gene: 109947258

Centisome position: 38.1

GC content: 38.13

Gene sequence:

>1146_bases
ATGGCATTAGACAAAAGGATTTGGATGCATTTTGATCTTTTACCTTTTATGTTTATCATCCCCTTGCTTGTGGTTTCTTT
TTTATTGATTTTTGAGAGCAGTGCGGTTTTGAGCTTGAAGCAAGGGATTTATTATACAATAGGGTTTGTGCTCTTTTGGA
TAGTGTTTTTTATCCCTTTTAGAAAGCTCGATCGGTGGCTTTTTGTGTTTTATTGGGCATGCATTATTTTATTGGCGTTA
GTGGATTTTGTGGGATCTAGCAAGCTTGGGGCACAACGATGGCTAGTCATTCCTTTTACTTCTATCACCTTACAGCCTAG
CGAACCTGTAAAAATCGCTATTCTTTTATTGTTGGCGCATTTGATTAAAATAAACCCACCCCCTTTTAATGGCTATGATT
GGGGCATGTTTTTAAAGCTTAGTTTTTACATTTGCTTACCGGCACTTTTGATTTTAAAACAGCCTGATTTAGGCACGGCC
CTTATTGTGTTAATCATGGGGTTTGGGATTTTATTGATCGTGGGTTTAAGGACTAGGGTATGGCTCTCTCTTTTAATCGC
TTTAATGGTGGCTTCGCCTATCGCTTATCATTTTTTACATGATTACCAAAAAAAGCGTATCGCGGACTTTCTTTCTGAAA
AGCCTAATTACCATGTCATGCAATCCATTATCGCTATTGGCTCAGGCGGTTTTTTAGGCAAATCTCAAGAAGCCTCCACT
CAAACCAAATTCAAATTCTTGCCTATCGCAACGAGCGATTTTATCTTTGCTTACTTTGTGGAGCGTTTTGGGTTTTTAGG
GGCTATGTTGCTTTTTGCGATTTATATAGGCTTAACTTTGCATTTATTTTTTTATATGTTTGAGAGCAACAGCGATTGGT
TTTTAAAAATTGTAGCCCTTGGGATTTCTATTTTGATCTTTGTTTATTCAAGCGTGAATATCGCCATGACCTTAGGGTTA
GCCCCTGTGGTGGGGATTCCCTTACCCTTATTCAGTTATGGGGGGAGTAGTTTTATCACTTTTATAATCTTGTTTGGGAT
CTTAGAAAACTTGCTTGCTTTTCGCTATATTTTTGGATACAATAGCAAACCATCTTTTGGGAATTTTGGATTCTTAGCTC
AGCTGGTCAGAGCACTCGGCTCATAA

Upstream 100 bases:

>100_bases
CCTGAAGTTAGCATGATAGCTTCTCTCTTTAAGGAGAATTATTTCAGTTTGGATATAATCAAAAAATTGAAACAATAAGA
TTAGGGGTTATGAAAAACGC

Downstream 100 bases:

>100_bases
CCGATTGGTCGTAGGTTCAAGTCCTACAGAATCCACCACTCCCACACTTCTTTTGATCCCCTTTTTAAGTGAAAAGCGAT
TGAACGCTTTCGTTATGATA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MALDKRIWMHFDLLPFMFIIPLLVVSFLLIFESSAVLSLKQGIYYTIGFVLFWIVFFIPFRKLDRWLFVFYWACIILLAL
VDFVGSSKLGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPPFNGYDWGMFLKLSFYICLPALLILKQPDLGTA
LIVLIMGFGILLIVGLRTRVWLSLLIALMVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSQEAST
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLTLHLFFYMFESNSDWFLKIVALGISILIFVYSSVNIAMTLGL
APVVGIPLPLFSYGGSSFITFIILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS

Sequences:

>Translated_381_residues
MALDKRIWMHFDLLPFMFIIPLLVVSFLLIFESSAVLSLKQGIYYTIGFVLFWIVFFIPFRKLDRWLFVFYWACIILLAL
VDFVGSSKLGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPPFNGYDWGMFLKLSFYICLPALLILKQPDLGTA
LIVLIMGFGILLIVGLRTRVWLSLLIALMVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSQEAST
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLTLHLFFYMFESNSDWFLKIVALGISILIFVYSSVNIAMTLGL
APVVGIPLPLFSYGGSSFITFIILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS
>Mature_380_residues
ALDKRIWMHFDLLPFMFIIPLLVVSFLLIFESSAVLSLKQGIYYTIGFVLFWIVFFIPFRKLDRWLFVFYWACIILLALV
DFVGSSKLGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPPFNGYDWGMFLKLSFYICLPALLILKQPDLGTAL
IVLIMGFGILLIVGLRTRVWLSLLIALMVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSQEASTQ
TKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLTLHLFFYMFESNSDWFLKIVALGISILIFVYSSVNIAMTLGLA
PVVGIPLPLFSYGGSSFITFIILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=368, Percent_Identity=37.2282608695652, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1786277, Length=316, Percent_Identity=31.0126582278481, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43151; Mature: 43019

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDKRIWMHFDLLPFMFIIPLLVVSFLLIFESSAVLSLKQGIYYTIGFVLFWIVFFIPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLDRWLFVFYWACIILLALVDFVGSSKLGAQRWLVIPFTSITLQPSEPVKIAILLLLAH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
LIKINPPPFNGYDWGMFLKLSFYICLPALLILKQPDLGTALIVLIMGFGILLIVGLRTRV
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLSLLIALMVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSQEAST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLTLHLFFYMFESNSDWFLKIVAL
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GISILIFVYSSVNIAMTLGLAPVVGIPLPLFSYGGSSFITFIILFGILENLLAFRYIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
NSKPSFGNFGFLAQLVRALGS
CCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ALDKRIWMHFDLLPFMFIIPLLVVSFLLIFESSAVLSLKQGIYYTIGFVLFWIVFFIPF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLDRWLFVFYWACIILLALVDFVGSSKLGAQRWLVIPFTSITLQPSEPVKIAILLLLAH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
LIKINPPPFNGYDWGMFLKLSFYICLPALLILKQPDLGTALIVLIMGFGILLIVGLRTRV
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLSLLIALMVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSQEAST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLTLHLFFYMFESNSDWFLKIVAL
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GISILIFVYSSVNIAMTLGLAPVVGIPLPLFSYGGSSFITFIILFGILENLLAFRYIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
NSKPSFGNFGFLAQLVRALGS
CCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]