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The map label for this gene is cmoB

Identifier: 109947189

GI number: 109947189

Start: 534865

End: 535653

Strand: Direct

Name: cmoB

Synonym: Hac_0607

Alternate gene names: 109947189

Gene position: 534865-535653 (Clockwise)

Preceding gene: 109947188

Following gene: 109947190

Centisome position: 34.42

GC content: 36.88

Gene sequence:

>789_bases
ATGCTTATTTGTAACGATAACCTCAATCAAAAAACCCTTTTAGAAGAAATCATGGCGTTAAGGCCATGGCGTAAAGGTCC
TTTTGAAATTTCTAAGATCAAGATTGATAGCGAATGGGATAGCTCTATTAAATGGGATCTAGTCAAGAACGCCACTTCTT
TAAAAGATAAAATCGTCGCTGATGTGGGTTGCAATAATGGCTATTACTTGTTTAAGATGCTAGAGCATGGGCCTAAAAGT
TTGGTGGGGTTTGATCCGGGCGTTTTAGTCAAAAAACAATTTGAATTTTTAGCCCCCTTTTTTGATAAAGAAAAAAAAAT
CATCTACAAGTCTTTAGGGGTGGAGGATTTGAATGAAAAATACCCTAACGCTTTTGATGTCATTTTTTGTTTAGGGGTGC
TATACCATAGAAAAAGCCCACTAGAAACTTTAAAAGCCTTGTATCATGCTTTGAAAATAGGGGGGGAGTTGGTGTTGGAT
ACGCTCATTATTGATTCGCCCCTAGACATTGCCCTTTGCCCTAAAAAAACTTATGCTAAAATGAAAAACGCTTATTTTAT
CCCTAGTATTAGTGCGCTAAAAGGGTGGTGTGAAAGGGTAGGGTTTGGAGATTTTGAAATCATTAGCGTTTTAAAGACTA
CGCCTAAAGAACAGCGTAAAACGGATTTTATTTTGGGGCAAAGTTTGGAAGATTTTTTGGATAAAAAAGATCATTCTAAA
ACTTTAGAGGGGTATGACGCCCCTTTGAGAGGGTATTTTAAAATGCTTAAATCATCAAGCAAGCGTTAG

Upstream 100 bases:

>100_bases
AGCGTTTAATTTCGCTTTTATTTATGGGATTAGCCCCAATCATTTAGAATCCCTTTTAAACCCCCCTCTTTTTAAAAAAA
CCCCCACGCTATGGTAAGTC

Downstream 100 bases:

>100_bases
TTTAAATAAAGGATTAAGATCATGCAAGAAATAATCACTCATGTGGATTATGACTCTTTACAAACTTGTAAGAATTTTCA
TTCAAGCGTGAGTGGGGAAT

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLICNDNLNQKTLLEEIMALRPWRKGPFEISKIKIDSEWDSSIKWDLVKNATSLKDKIVADVGCNNGYYLFKMLEHGPKS
LVGFDPGVLVKKQFEFLAPFFDKEKKIIYKSLGVEDLNEKYPNAFDVIFCLGVLYHRKSPLETLKALYHALKIGGELVLD
TLIIDSPLDIALCPKKTYAKMKNAYFIPSISALKGWCERVGFGDFEIISVLKTTPKEQRKTDFILGQSLEDFLDKKDHSK
TLEGYDAPLRGYFKMLKSSSKR

Sequences:

>Translated_262_residues
MLICNDNLNQKTLLEEIMALRPWRKGPFEISKIKIDSEWDSSIKWDLVKNATSLKDKIVADVGCNNGYYLFKMLEHGPKS
LVGFDPGVLVKKQFEFLAPFFDKEKKIIYKSLGVEDLNEKYPNAFDVIFCLGVLYHRKSPLETLKALYHALKIGGELVLD
TLIIDSPLDIALCPKKTYAKMKNAYFIPSISALKGWCERVGFGDFEIISVLKTTPKEQRKTDFILGQSLEDFLDKKDHSK
TLEGYDAPLRGYFKMLKSSSKR
>Mature_262_residues
MLICNDNLNQKTLLEEIMALRPWRKGPFEISKIKIDSEWDSSIKWDLVKNATSLKDKIVADVGCNNGYYLFKMLEHGPKS
LVGFDPGVLVKKQFEFLAPFFDKEKKIIYKSLGVEDLNEKYPNAFDVIFCLGVLYHRKSPLETLKALYHALKIGGELVLD
TLIIDSPLDIALCPKKTYAKMKNAYFIPSISALKGWCERVGFGDFEIISVLKTTPKEQRKTDFILGQSLEDFLDKKDHSK
TLEGYDAPLRGYFKMLKSSSKR

Specific function: Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoB family

Homologues:

Organism=Escherichia coli, GI1788178, Length=242, Percent_Identity=44.2148760330579, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOB_HELAH (Q17Y58)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_664417.1
- ProteinModelPortal:   Q17Y58
- SMR:   Q17Y58
- STRING:   Q17Y58
- GeneID:   4177391
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0607
- NMPDR:   fig|382638.8.peg.589
- eggNOG:   COG0500
- HOGENOM:   HBG296882
- OMA:   DVIFCLG
- PhylomeDB:   Q17Y58
- ProtClustDB:   PRK15068
- BioCyc:   HACI382638:HAC_0607-MONOMER
- HAMAP:   MF_01590
- InterPro:   IPR010017
- TIGRFAMs:   TIGR00452

Pfam domain/function: PF08003 Methyltransf_9

EC number: NA

Molecular weight: Translated: 29961; Mature: 29961

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLICNDNLNQKTLLEEIMALRPWRKGPFEISKIKIDSEWDSSIKWDLVKNATSLKDKIVA
CEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
DVGCNNGYYLFKMLEHGPKSLVGFDPGVLVKKQFEFLAPFFDKEKKIIYKSLGVEDLNEK
HCCCCCCEEEHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
YPNAFDVIFCLGVLYHRKSPLETLKALYHALKIGGELVLDTLIIDSPLDIALCPKKTYAK
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEECCHHHHHH
MKNAYFIPSISALKGWCERVGFGDFEIISVLKTTPKEQRKTDFILGQSLEDFLDKKDHSK
HHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHCCCCCCH
TLEGYDAPLRGYFKMLKSSSKR
HHCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLICNDNLNQKTLLEEIMALRPWRKGPFEISKIKIDSEWDSSIKWDLVKNATSLKDKIVA
CEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
DVGCNNGYYLFKMLEHGPKSLVGFDPGVLVKKQFEFLAPFFDKEKKIIYKSLGVEDLNEK
HCCCCCCEEEHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHH
YPNAFDVIFCLGVLYHRKSPLETLKALYHALKIGGELVLDTLIIDSPLDIALCPKKTYAK
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCEEECCHHHHHH
MKNAYFIPSISALKGWCERVGFGDFEIISVLKTTPKEQRKTDFILGQSLEDFLDKKDHSK
HHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHCCCCCCH
TLEGYDAPLRGYFKMLKSSSKR
HHCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA