Click here to switch to the map view.

The map label for this gene is mtaD [H]

Identifier: 109947118

GI number: 109947118

Start: 452016

End: 453242

Strand: Direct

Name: mtaD [H]

Synonym: Hac_0525

Alternate gene names: 109947118

Gene position: 452016-453242 (Clockwise)

Preceding gene: 109947117

Following gene: 109947119

Centisome position: 29.09

GC content: 38.96

Gene sequence:

>1227_bases
ATGCAAATCATAGGAGCGTCTTTAGTTTTTTTGTGTAATGAAAAATGCGAAGTGTTAGAAGATCATGGCGTAGTCTTTGA
TGAAAACATTATTGAAGTGGGCGATTACCACAATTTGACGCTCAAATACCCTCACTTAAAAGTGCAGTTTTTTGAAAACT
CCGTTCTTTTGCCCGCTTTTATCAACACGCACACCCATTTTGAATTTTCCAACAACAAGGCGAGTTTTGATTATGGGAGT
TTTTCTGGCTGGTTAGGGAGCGTGTTGAATAATGGGGGGGTGATTTTAGAAAATTGCCAAGGGGCTATCCAAAACGCCAT
CACTACGCAATTAAAAAGCGGAGTAGGGAGTGTGGGGGCGATTTCTAACCACTTGATAGAAGTGGGTTTATTGAAAGAAA
GCCCTTTGAATGCCGTCGTGTTTTTGGAGTTTTTAGGGAGTAGCTATTCTTTAGAAAAATTAAAGGCGTTTGAGAAAAAA
TTTAAGGAGTTAAAAAATTTAGAAGATGAAAAACTCAAAGCCGCTCTCGCTGTGCATGCCCCTTATTCGGTTCAAAAAGA
CATGGCTTTAAGCGTTATCCAACTGGCTAAAGATTCACAAAGCCTGCTTTCTACGCATTTTTTAGAATCGTTTGAAGAAC
TAGAATGGGTAGAAAATTCTAAAGGGTGGTTTGAGAATTTTTACCAGCATTTTTTGAAAGAGTCTAATTTCAAATCGCTC
TATAAAGGCGCGAATGATTATATTGACATGTTTAAAGACACGCACACTTTATTCGTGCATAACCAATTCGCTTCTTTGGA
GGCGTTAAAAAGGATCAAATCTCAAGTGGAAAACGCTTTTTTAATCACATGCCCTTTTTCTAACCGCTTGTTAAGTGGGA
AAGCTTTGGATTTAGAAAGGGTTAGAGAAGCAAATTTAAGCGTGAGCGTTGCTACTGATGGCTTGAGCTCCAATATTTCG
CTGAGCCTTTTAGATGAATTAAGGGCGTTTTTGCTCACCCACAACATGCCGTTATTAGAATTAGCCAAAATGGCCCTTTT
AGGGGCTACGCGTCATGGGGCTAAAGCTTTAGCTTTGAATAATGGCGAGATACAAGTCAACAAAAGGGCGGATCTGAGCG
TGTTTGGTTTTAATGAAAAATTCACTAAAGAGCAAGCGATTTTACAATTTTTATTGCATGCTAAAGAGGTGGAATGCTTG
TTTTTAGGGGGGAAAAGGGTAACTTAA

Upstream 100 bases:

>100_bases
GAGTGAGTAATAAAAATTCGCCCTTTTATGGTTTAGAATTGCATGGCGAAATTCAAAGAATGATCTTAAAAGGGCAAACC
ACATTTATTAAGGAGAATGC

Downstream 100 bases:

>100_bases
AAAAGTAATTGATGGTTTTGTTTTTAAGGAGTTCTAAATAAAAATGCTTTTAGCATTTTTTAAAATAAAAAAGTCTAATT
TATTCTAAAGACAGAATGCG

Product: chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MQIIGASLVFLCNEKCEVLEDHGVVFDENIIEVGDYHNLTLKYPHLKVQFFENSVLLPAFINTHTHFEFSNNKASFDYGS
FSGWLGSVLNNGGVILENCQGAIQNAITTQLKSGVGSVGAISNHLIEVGLLKESPLNAVVFLEFLGSSYSLEKLKAFEKK
FKELKNLEDEKLKAALAVHAPYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESNFKSL
YKGANDYIDMFKDTHTLFVHNQFASLEALKRIKSQVENAFLITCPFSNRLLSGKALDLERVREANLSVSVATDGLSSNIS
LSLLDELRAFLLTHNMPLLELAKMALLGATRHGAKALALNNGEIQVNKRADLSVFGFNEKFTKEQAILQFLLHAKEVECL
FLGGKRVT

Sequences:

>Translated_408_residues
MQIIGASLVFLCNEKCEVLEDHGVVFDENIIEVGDYHNLTLKYPHLKVQFFENSVLLPAFINTHTHFEFSNNKASFDYGS
FSGWLGSVLNNGGVILENCQGAIQNAITTQLKSGVGSVGAISNHLIEVGLLKESPLNAVVFLEFLGSSYSLEKLKAFEKK
FKELKNLEDEKLKAALAVHAPYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESNFKSL
YKGANDYIDMFKDTHTLFVHNQFASLEALKRIKSQVENAFLITCPFSNRLLSGKALDLERVREANLSVSVATDGLSSNIS
LSLLDELRAFLLTHNMPLLELAKMALLGATRHGAKALALNNGEIQVNKRADLSVFGFNEKFTKEQAILQFLLHAKEVECL
FLGGKRVT
>Mature_408_residues
MQIIGASLVFLCNEKCEVLEDHGVVFDENIIEVGDYHNLTLKYPHLKVQFFENSVLLPAFINTHTHFEFSNNKASFDYGS
FSGWLGSVLNNGGVILENCQGAIQNAITTQLKSGVGSVGAISNHLIEVGLLKESPLNAVVFLEFLGSSYSLEKLKAFEKK
FKELKNLEDEKLKAALAVHAPYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESNFKSL
YKGANDYIDMFKDTHTLFVHNQFASLEALKRIKSQVENAFLITCPFSNRLLSGKALDLERVREANLSVSVATDGLSSNIS
LSLLDELRAFLLTHNMPLLELAKMALLGATRHGAKALALNNGEIQVNKRADLSVFGFNEKFTKEQAILQFLLHAKEVECL
FLGGKRVT

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 45637; Mature: 45637

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIIGASLVFLCNEKCEVLEDHGVVFDENIIEVGDYHNLTLKYPHLKVQFFENSVLLPAF
CCEECCEEEEHCCCHHHHHHHCCEEEECCEEEECCCCCEEEECCCEEEEEECCCEEEEEE
INTHTHFEFSNNKASFDYGSFSGWLGSVLNNGGVILENCQGAIQNAITTQLKSGVGSVGA
ECCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCCHHH
ISNHLIEVGLLKESPLNAVVFLEFLGSSYSLEKLKAFEKKFKELKNLEDEKLKAALAVHA
HHHHHEEEEEECCCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHEEEC
PYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESNFKSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHH
YKGANDYIDMFKDTHTLFVHNQFASLEALKRIKSQVENAFLITCPFSNRLLSGKALDLER
HCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHH
VREANLSVSVATDGLSSNISLSLLDELRAFLLTHNMPLLELAKMALLGATRHGAKALALN
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEE
NGEIQVNKRADLSVFGFNEKFTKEQAILQFLLHAKEVECLFLGGKRVT
CCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
>Mature Secondary Structure
MQIIGASLVFLCNEKCEVLEDHGVVFDENIIEVGDYHNLTLKYPHLKVQFFENSVLLPAF
CCEECCEEEEHCCCHHHHHHHCCEEEECCEEEECCCCCEEEECCCEEEEEECCCEEEEEE
INTHTHFEFSNNKASFDYGSFSGWLGSVLNNGGVILENCQGAIQNAITTQLKSGVGSVGA
ECCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCCCHHH
ISNHLIEVGLLKESPLNAVVFLEFLGSSYSLEKLKAFEKKFKELKNLEDEKLKAALAVHA
HHHHHEEEEEECCCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHEEEC
PYSVQKDMALSVIQLAKDSQSLLSTHFLESFEELEWVENSKGWFENFYQHFLKESNFKSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHH
YKGANDYIDMFKDTHTLFVHNQFASLEALKRIKSQVENAFLITCPFSNRLLSGKALDLER
HCCHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHH
VREANLSVSVATDGLSSNISLSLLDELRAFLLTHNMPLLELAKMALLGATRHGAKALALN
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEE
NGEIQVNKRADLSVFGFNEKFTKEQAILQFLLHAKEVECLFLGGKRVT
CCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA