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The map label for this gene is ail [H]

Identifier: 108812424

GI number: 108812424

Start: 2542135

End: 2542686

Strand: Reverse

Name: ail [H]

Synonym: YPN_2263

Alternate gene names: 108812424

Gene position: 2542686-2542135 (Counterclockwise)

Preceding gene: 108812426

Following gene: 108812423

Centisome position: 56.07

GC content: 37.68

Gene sequence:

>552_bases
ATGAAAAATAAAACCACATTGGCTGCATTTATAACAGCGATCTTATTAAGCAGTTCAGCGGCCTATGCGGCAGGGGATCG
TACCATCTCATTGGGGTATGCTCAGGGAGATGTAAGACTCGGTGATGGAAATCGAAAAGACATTAGATTGGACGATGATC
TTAAAGGGATTAATGTTAAATATCTCCATAAGTTGAGTGAAATGTTCGGTGCAATAGGCTCTTTTACTTACACGGATTTA
AATTATGATTATCTAAATAATAATGTCAAAATTGGGGATGCATCCTTTGATTATTATTCGCTGATGGTTGGGCCCAGCGT
ACATTTTAATGAGTTTTTCAGCATGTATGCATTATTGGGAATTGGGCATGGGAACGCGAAAGCATCTGTATTAGGTTACG
GTAAAAAAGAGGAGCAAGACTCTTTGGCATATGGTGTTGGGATGCAATTTAATCCACTTAACAATATTGCTATTGATGCT
TCATACGAGTATACAAAACTTAAAGATGCTAATATCGGTACATGGGTTTTAGGCATTGGCTATCGTTTTTAA

Upstream 100 bases:

>100_bases
AAAAATGGAATTTTGTGTTTGTGATGGACTACTGGCTGAATATTAGTGACCAATGCGACGATACCGTAATCTAAGATAAT
AATTTAAGGATAAAAGTTTA

Downstream 100 bases:

>100_bases
TAAAATACTTTCTATATAATAATAACAGCCGTATTAGTTCACTGTGCGGCTGTTTTTTCATCAGTTGTAAAGAGATTCAT
AACGATAAAAAATTGAGTCC

Product: attachment invasion locus protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKNKTTLAAFITAILLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGNAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYTKLKDANIGTWVLGIGYRF

Sequences:

>Translated_183_residues
MKNKTTLAAFITAILLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGNAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYTKLKDANIGTWVLGIGYRF
>Mature_183_residues
MKNKTTLAAFITAILLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVKYLHKLSEMFGAIGSFTYTDL
NYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLGIGHGNAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDA
SYEYTKLKDANIGTWVLGIGYRF

Specific function: Promotes the invasion of pathogenic bacteria into eukaryotic cells by an unknown mechanism [H]

COG id: COG3637

COG function: function code M; Opacity protein and related surface antigens

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ail/ompX/pagC/lom family [H]

Homologues:

Organism=Escherichia coli, GI1787034, Length=190, Percent_Identity=33.1578947368421, Blast_Score=103, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000758
- InterPro:   IPR011250 [H]

Pfam domain/function: PF06316 Ail_Lom [H]

EC number: NA

Molecular weight: Translated: 20110; Mature: 20110

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00695 ENT_VIR_OMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKTTLAAFITAILLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVK
CCCCHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCEEECCCCCCCEEECCCCCCCCHH
YLHKLSEMFGAIGSFTYTDLNYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLG
HHHHHHHHHHHHCCEEEECCCHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHC
IGHGNAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDASYEYTKLKDANIGTWVLGIG
CCCCCCCEEEEECCCCCCCCCEEEECCCEECCCCCEEEECCCCEEEECCCCCCEEEEEEC
YRF
CCC
>Mature Secondary Structure
MKNKTTLAAFITAILLSSSAAYAAGDRTISLGYAQGDVRLGDGNRKDIRLDDDLKGINVK
CCCCHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCEEECCCCCCCEEECCCCCCCCHH
YLHKLSEMFGAIGSFTYTDLNYDYLNNNVKIGDASFDYYSLMVGPSVHFNEFFSMYALLG
HHHHHHHHHHHHCCEEEECCCHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHC
IGHGNAKASVLGYGKKEEQDSLAYGVGMQFNPLNNIAIDASYEYTKLKDANIGTWVLGIG
CCCCCCCEEEEECCCCCCCCCEEEECCCEECCCCCEEEECCCCEEEECCCCCCEEEEEEC
YRF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1688838 [H]