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The map label for this gene is pgsA [H]

Identifier: 108812418

GI number: 108812418

Start: 2537069

End: 2537617

Strand: Reverse

Name: pgsA [H]

Synonym: YPN_2257

Alternate gene names: 108812418

Gene position: 2537617-2537069 (Counterclockwise)

Preceding gene: 108812419

Following gene: 108812416

Centisome position: 55.96

GC content: 46.08

Gene sequence:

>549_bases
ATGCAATTGAATATACCGACTTGGCTTACCTTGTTCCGTGTTGTGCTCATCCCATTCTTCGTTCTGGCGTTTTATTTGCC
GTTCGTCTGGGCTCCGATGGTTTGCGCCATCATATTTGTGTTTGCCGCGGCAACCGATTGGTTTGATGGCTTTTTAGCTC
GACGTTGGAAACAGACAACCCGTTTTGGTGCTTTCCTTGATCCTGTAGCGGATAAAGTTATGGTAGCCGTTGCATTAGTA
TTGGTTGCTGAACATTACCACTCTTGGTGGATTACATTACCGGCTGCAACGATGATCGCCCGAGAAATTATCATTTCGTC
TCTTAGAGAATGGATGGCAGAAATTGGTAAACGCAGCAGCGTTGCGGTGTCATGGGTAGGTAAGGTAAAGACGATGGCAC
AAATGGGGTCACTTGTTGGGTTGCTTTGGCGCCCTGACCACAATGTTGAACTTGCCAGTTTCGTTTTACTTTATATTGCT
GCTGTACTGACATTCTGGTCAATGTTCCAATATTTGAACGCTGCCTGGAGTGATTTGCTCGAACCTTGA

Upstream 100 bases:

>100_bases
CAAGCATTGGCAGAAAAAATCCACAATGCATTGAAACACTGAAGCTAATGTTGCACCATACTCATAGTGTCCACACCAGC
CAGATAGTTATCGTAGCATT

Downstream 100 bases:

>100_bases
TCGAAGCGCCGTAAAAAGCAGCAAACGAACGAATAATTCAGATAATTTTATTGACTCATTGCGTCAGGTAAGTAGAATGC
ATCGCATCAGACGGCAGCAA

Product: phosphatidylglycerophosphate synthetase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALV
LVAEHYHSWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWVGKVKTMAQMGSLVGLLWRPDHNVELASFVLLYIA
AVLTFWSMFQYLNAAWSDLLEP

Sequences:

>Translated_182_residues
MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALV
LVAEHYHSWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWVGKVKTMAQMGSLVGLLWRPDHNVELASFVLLYIA
AVLTFWSMFQYLNAAWSDLLEP
>Mature_182_residues
MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALV
LVAEHYHSWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWVGKVKTMAQMGSLVGLLWRPDHNVELASFVLLYIA
AVLTFWSMFQYLNAAWSDLLEP

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=181, Percent_Identity=75.1381215469613, Blast_Score=276, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20806; Mature: 20806

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKVMVAVALVLVAEHYHSWWITLPAATMIAREIIISSLREWMAEIGKRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVSWVGKVKTMAQMGSLVGLLWRPDHNVELASFVLLYIAAVLTFWSMFQYLNAAWSDLL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EP
CC
>Mature Secondary Structure
MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGAFLDPVADKVMVAVALVLVAEHYHSWWITLPAATMIAREIIISSLREWMAEIGKRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVSWVGKVKTMAQMGSLVGLLWRPDHNVELASFVLLYIAAVLTFWSMFQYLNAAWSDLL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA