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The map label for this gene is fabH [H]

Identifier: 108812194

GI number: 108812194

Start: 2294573

End: 2295523

Strand: Reverse

Name: fabH [H]

Synonym: YPN_2032

Alternate gene names: 108812194

Gene position: 2295523-2294573 (Counterclockwise)

Preceding gene: 108812195

Following gene: 108812193

Centisome position: 50.62

GC content: 50.79

Gene sequence:

>951_bases
ATGTATACTAAGATTCTCGGTACGGGGAGTTATCTGCCCGTACAAGTGCGCAGCAATGCTGATTTAGAAAAAATGGTGGA
TACGTCAGATGAGTGGATTGTCACTCGTACTGGTATCCGTGAGCGGCGTATTGCAGGCCTTGACGAAACAGTCGCGACTA
TGGGCTTCCAGGCGGCAGAAAAAGCGCTGGAAATGGCCGGTATTGATAAGGACGATATCGGGTTGATTATCGTTGCGACC
ACCTCTTCAAGCCATGCTTTCCCAAGTTCGGCTTGCCAGGTGCAGCGAATGCTCGGTATCAAAGATGCAGCTTCTTTTGA
TTTGGCTGCGGCTTGCGCGGGTTTTACCTATGCGCTGAGTGTTGCTGACCAGTATGTTAAGAGTGGTGCGGTCAAGCATG
CCATTGTTATTGGGTCAGATGTATTGTCCCGTGCATTGGATCCAGAAGATCGTGGTACGATCATTCTGTTTGGCGATGGC
GCTGGCGCGGTGGTACTTGGTGCATCTGAGCAACCAGGTATTATGTCTACGCATTTACATGCTGATGGTCGTTATGGCGA
GTTGCTCGCTTTACCGTATCCAGACCGTCAGCAGGACCAACCTGCCTACGTCACGATGGCAGGCAATGAAGTTTTTAAAG
TTGCGGTAACGGAACTGGCCCACATTGTGGATGAAACATTGCAGGCTAATAATCTGGATCGCACTGCGCTCGATTGGTTG
GTGCCACATCAGGCTAACCTGCGTATTATTAGCGCTACGGCTAAAAAGTTAGGCATGGGGATGGATAAAGTGGTGATCAC
GCTTGATCGCCATGGGAACACCTCCGCGGCATCAGTGCCTTCGGCATTCGATGAAGCAGTGCGAGATGGGCGAATTCAAC
GTGGGCAGTTGGTATTGCTTGAGGCGTTTGGCGGTGGATTTACCTGGGGTTCTGCACTGGTTCGTTTTTGA

Upstream 100 bases:

>100_bases
CGTAGCTATCGAGCAGGCAGTGCAGGCGGTGCAGCGGCAAGTTCCTGAACGGATTGCCGCGCGCCTTGAAGCGGTATTAC
CCAAGAGTGACTGATCGTAC

Downstream 100 bases:

>100_bases
TTTAACCGGCCGTTTTTTGATGTAACAGGAATGCAAAATGTCGAAATTTGCAATGGTATTTCCAGGTCAGGGTTCTCAGT
CCCTCGGCATGCTGGCCGAT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKDDIGLIIVAT
TSSSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLSRALDPEDRGTIILFGDG
AGAVVLGASEQPGIMSTHLHADGRYGELLALPYPDRQQDQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRTALDWL
VPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAFDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF

Sequences:

>Translated_316_residues
MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKDDIGLIIVAT
TSSSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLSRALDPEDRGTIILFGDG
AGAVVLGASEQPGIMSTHLHADGRYGELLALPYPDRQQDQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRTALDWL
VPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAFDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF
>Mature_316_residues
MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKDDIGLIIVAT
TSSSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLSRALDPEDRGTIILFGDG
AGAVVLGASEQPGIMSTHLHADGRYGELLALPYPDRQQDQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRTALDWL
VPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAFDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=317, Percent_Identity=81.0725552050473, Blast_Score=535, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 33739; Mature: 33739

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAE
CCEEEEECCCEEEEEECCCCCHHHHHCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHH
KALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALS
HHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VADQYVKSGAVKHAIVIGSDVLSRALDPEDRGTIILFGDGAGAVVLGASEQPGIMSTHLH
HHHHHHHCCCCEEEEEECHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGRYGELLALPYPDRQQDQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRTALDWL
CCCCCCCEEEECCCCCCCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHC
VPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAFDEAVRDGRIQRGQLVLL
CCCCCCEEEEEECHHHHCCCCCEEEEEEECCCCCCHHCCCHHHHHHHHCCCCCCCCEEEE
EAFGGGFTWGSALVRF
EECCCCCCHHHHHHCC
>Mature Secondary Structure
MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAE
CCEEEEECCCEEEEEECCCCCHHHHHCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHH
KALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALS
HHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VADQYVKSGAVKHAIVIGSDVLSRALDPEDRGTIILFGDGAGAVVLGASEQPGIMSTHLH
HHHHHHHCCCCEEEEEECHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEEE
ADGRYGELLALPYPDRQQDQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRTALDWL
CCCCCCCEEEECCCCCCCCCCEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCHHHHHHC
VPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPSAFDEAVRDGRIQRGQLVLL
CCCCCCEEEEEECHHHHCCCCCEEEEEEECCCCCCHHCCCHHHHHHHHCCCCCCCCEEEE
EAFGGGFTWGSALVRF
EECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA