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The map label for this gene is hinT [H]

Identifier: 108812180

GI number: 108812180

Start: 2281289

End: 2281642

Strand: Reverse

Name: hinT [H]

Synonym: YPN_2018

Alternate gene names: 108812180

Gene position: 2281642-2281289 (Counterclockwise)

Preceding gene: 108812181

Following gene: 108812179

Centisome position: 50.32

GC content: 49.44

Gene sequence:

>354_bases
ATGGCCGAAGAAACGATTTTCAGCAAAATTATCCGCCGCGAAATCCCTGCCGATGTGGTTTATCAAGATGAGCTGGTGAC
GGCGTTTCGTGATATTGCCCCACAAGCACCGACCCATATCTTAATCATTCCTAATGTTTTGATCCCAACAGTGAATGATG
TCACGGCTGAACATGAGGCGGCACTTGGCCGTATGGTAACCGTAGCCGCTAAGCTGGCCGAGCAGGAAGGTATTGCAGAA
GACGGCTATCGGTTAATTATCAACTGTAACCACCATGCCGGGCAGGTTGTCTATCATATTCATATGCATTTGGTCGGTGG
CCGTGAGCTTGGCCCTTTGTTGCCCCACAAATAG

Upstream 100 bases:

>100_bases
TGTCATTCGCCCTGGAAAATGTCTAATCAGGTTGAAACCAATAGAAATTGTCGCTCATACTGCATGTTCTTCAATTTTAT
AATGACCAAGGAAATGTGTT

Downstream 100 bases:

>100_bases
CCCTATAATAAGTAAGTTTTGCAGAGGTCAACTTATGCGCGATCTTAAAACGTTGCTATTACCCGTGATATTGTTCGCTT
GCGTAACAACATTGCTGGGG

Product: purine nucleoside phosphoramidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MAEETIFSKIIRREIPADVVYQDELVTAFRDIAPQAPTHILIIPNVLIPTVNDVTAEHEAALGRMVTVAAKLAEQEGIAE
DGYRLIINCNHHAGQVVYHIHMHLVGGRELGPLLPHK

Sequences:

>Translated_117_residues
MAEETIFSKIIRREIPADVVYQDELVTAFRDIAPQAPTHILIIPNVLIPTVNDVTAEHEAALGRMVTVAAKLAEQEGIAE
DGYRLIINCNHHAGQVVYHIHMHLVGGRELGPLLPHK
>Mature_116_residues
AEETIFSKIIRREIPADVVYQDELVTAFRDIAPQAPTHILIIPNVLIPTVNDVTAEHEAALGRMVTVAAKLAEQEGIAED
GYRLIINCNHHAGQVVYHIHMHLVGGRELGPLLPHK

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=109, Percent_Identity=45.8715596330275, Blast_Score=110, Evalue=2e-25,
Organism=Homo sapiens, GI4885413, Length=107, Percent_Identity=43.9252336448598, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1787346, Length=117, Percent_Identity=84.6153846153846, Blast_Score=188, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17506713, Length=109, Percent_Identity=41.2844036697248, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574010, Length=109, Percent_Identity=44.0366972477064, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24581222, Length=109, Percent_Identity=44.0366972477064, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12943; Mature: 12812

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEETIFSKIIRREIPADVVYQDELVTAFRDIAPQAPTHILIIPNVLIPTVNDVTAEHEA
CCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCEEEEEECCEECCCCCCCCHHHHH
ALGRMVTVAAKLAEQEGIAEDGYRLIINCNHHAGQVVYHIHMHLVGGRELGPLLPHK
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
AEETIFSKIIRREIPADVVYQDELVTAFRDIAPQAPTHILIIPNVLIPTVNDVTAEHEA
CHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCEEEEEECCEECCCCCCCCHHHHH
ALGRMVTVAAKLAEQEGIAEDGYRLIINCNHHAGQVVYHIHMHLVGGRELGPLLPHK
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]