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The map label for this gene is degS [H]

Identifier: 108798028

GI number: 108798028

Start: 1151746

End: 1152951

Strand: Reverse

Name: degS [H]

Synonym: Mmcs_1055

Alternate gene names: 108798028

Gene position: 1152951-1151746 (Counterclockwise)

Preceding gene: 108798029

Following gene: 108798026

Centisome position: 20.21

GC content: 70.81

Gene sequence:

>1206_bases
GTGACAACGCGAGCGCTGCTGACCGCCGACCGCGAACTGGCCCTGCTGCGCGAGCTCATCCAGGCGGCCTCGAGCGGGCC
GGGGGTGGAGCCGCTCGCGGCCGCGGCCGCCCGCATGATCACCGCGGCCACCCGCACCGACGTCTGTTTCGTCCATGTGC
TCGACGACTCCGACCGGTCGCTGACACTGGCCGGGGCCACGCCGCCGTTCGACAGCCAGATCGGCAAGATCCGGCTACCG
CTGGGCCAGGGCATCTCCGGCTGGGTGGCCAGCCACCGCGAGCCGGTGGTGATCGGCCACGACAAGGAGTCCGATCCGCG
CTACATGCCCTTCCAGTCGTTGCGCGGCAAGGACTTCACGTCGATGGTGTCGGTGCCGATGGAGACCGACCCCGGCGGGC
TGGTCGGGGTCCTCAACGTGCACACCGTCGAACGTCGCGACTTCTCCGAGCGCGACGTGGAACTGCTCCTGGTGATCGGC
CGGCTCATCGCCGGCGCGCTGCACCAGGCGCGGCTGCACCGGCAGTTGGTGGCGCGCGAACGCGCGCACGAGAACTTCGT
CGAGCAGGTGATCGAGGCCCAGGAGATCGAACGCCGACGGCTCGCCGGCGACATCCACGACGGGATCTCGCAGCGGCTGG
TGACGCTGTCCTACCGGCTCGACGCCGCGGTCCGCGCGATCGGCGATCCGGAAGTGGTGTCCGAACAACTCGGCAAGGCC
CGTGAACTGGTGGCGCTGACGCTGGGCGAGGCGCGTGCCGCGATCAGCGGGCTGCGTCCGCCGGTGCTCGACGATCTCGG
CCTGGCGGGCGGCCTGGCGAGCCTGGCCAGGTCCATCCCCCAGGTCGACATCGACGTCGATCTCGCCGAACGCCGGCTCC
CCGACCACATCGAGCTGGCGCTGTACCGCATCGCCCAGGAGTGTCTGCAGAACGTGGTCAAACACTCCGGCGCCGCGACG
GCCCGGTTGACGTTCGGGGTGGCCGACGACGCCACGGGCCAGACAGCGCGGCTCGAGATCATCGACGACGGCGTGGGATT
CGACACTTTCGAACATCCCCTCGGCGGCGACGAGATGGGCGGCTACGGGCTGTTGTCGATGGCCGAGCGCGCGGAGATCG
TCGGTGGCCGCCTGAACATCCGGTCCCGGCCGGGTGCGGGGACGGCGGTGACGGCGACGATCCCGCTGCCCTCGGTCGCC
GACTGA

Upstream 100 bases:

>100_bases
AGGAGACCGTGAAGACCCATCTGCGGTCGATCTACCGCAAACTCGGCGTCGGTGACCGCGCCGGTGCGGTGGCGACGGCG
CTGCGCGAGGGGATTTACCA

Downstream 100 bases:

>100_bases
GGTCAGCCCGGCAACGTGCAGTCGTCGCGCCGGTGCGCCTCGACGGCCGCGACGACGTCGTCGGCGATCTCCCGCAGCAC
CTCGAGGCGGTCGGGTCCGA

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTTRALLTADRELALLRELIQAASSGPGVEPLAAAAARMITAATRTDVCFVHVLDDSDRSLTLAGATPPFDSQIGKIRLP
LGQGISGWVASHREPVVIGHDKESDPRYMPFQSLRGKDFTSMVSVPMETDPGGLVGVLNVHTVERRDFSERDVELLLVIG
RLIAGALHQARLHRQLVARERAHENFVEQVIEAQEIERRRLAGDIHDGISQRLVTLSYRLDAAVRAIGDPEVVSEQLGKA
RELVALTLGEARAAISGLRPPVLDDLGLAGGLASLARSIPQVDIDVDLAERRLPDHIELALYRIAQECLQNVVKHSGAAT
ARLTFGVADDATGQTARLEIIDDGVGFDTFEHPLGGDEMGGYGLLSMAERAEIVGGRLNIRSRPGAGTAVTATIPLPSVA
D

Sequences:

>Translated_401_residues
MTTRALLTADRELALLRELIQAASSGPGVEPLAAAAARMITAATRTDVCFVHVLDDSDRSLTLAGATPPFDSQIGKIRLP
LGQGISGWVASHREPVVIGHDKESDPRYMPFQSLRGKDFTSMVSVPMETDPGGLVGVLNVHTVERRDFSERDVELLLVIG
RLIAGALHQARLHRQLVARERAHENFVEQVIEAQEIERRRLAGDIHDGISQRLVTLSYRLDAAVRAIGDPEVVSEQLGKA
RELVALTLGEARAAISGLRPPVLDDLGLAGGLASLARSIPQVDIDVDLAERRLPDHIELALYRIAQECLQNVVKHSGAAT
ARLTFGVADDATGQTARLEIIDDGVGFDTFEHPLGGDEMGGYGLLSMAERAEIVGGRLNIRSRPGAGTAVTATIPLPSVA
D
>Mature_400_residues
TTRALLTADRELALLRELIQAASSGPGVEPLAAAAARMITAATRTDVCFVHVLDDSDRSLTLAGATPPFDSQIGKIRLPL
GQGISGWVASHREPVVIGHDKESDPRYMPFQSLRGKDFTSMVSVPMETDPGGLVGVLNVHTVERRDFSERDVELLLVIGR
LIAGALHQARLHRQLVARERAHENFVEQVIEAQEIERRRLAGDIHDGISQRLVTLSYRLDAAVRAIGDPEVVSEQLGKAR
ELVALTLGEARAAISGLRPPVLDDLGLAGGLASLARSIPQVDIDVDLAERRLPDHIELALYRIAQECLQNVVKHSGAATA
RLTFGVADDATGQTARLEIIDDGVGFDTFEHPLGGDEMGGYGLLSMAERAEIVGGRLNIRSRPGAGTAVTATIPLPSVAD

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=227, Percent_Identity=27.3127753303965, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082311, Length=246, Percent_Identity=30.0813008130081, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43022; Mature: 42890

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRALLTADRELALLRELIQAASSGPGVEPLAAAAARMITAATRTDVCFVHVLDDSDRS
CCCCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
LTLAGATPPFDSQIGKIRLPLGQGISGWVASHREPVVIGHDKESDPRYMPFQSLRGKDFT
EEEECCCCCCCCCCCEEEECCCCCCHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCCCCH
SMVSVPMETDPGGLVGVLNVHTVERRDFSERDVELLLVIGRLIAGALHQARLHRQLVARE
HHEECCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAHENFVEQVIEAQEIERRRLAGDIHDGISQRLVTLSYRLDAAVRAIGDPEVVSEQLGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RELVALTLGEARAAISGLRPPVLDDLGLAGGLASLARSIPQVDIDVDLAERRLPDHIELA
HHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHCCCCEEECCHHHHCCCHHHHHH
LYRIAQECLQNVVKHSGAATARLTFGVADDATGQTARLEIIDDGVGFDTFEHPLGGDEMG
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
GYGLLSMAERAEIVGGRLNIRSRPGAGTAVTATIPLPSVAD
CCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TTRALLTADRELALLRELIQAASSGPGVEPLAAAAARMITAATRTDVCFVHVLDDSDRS
CCCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCE
LTLAGATPPFDSQIGKIRLPLGQGISGWVASHREPVVIGHDKESDPRYMPFQSLRGKDFT
EEEECCCCCCCCCCCEEEECCCCCCHHHHHCCCCCEEEECCCCCCCCCCCHHHCCCCCCH
SMVSVPMETDPGGLVGVLNVHTVERRDFSERDVELLLVIGRLIAGALHQARLHRQLVARE
HHEECCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAHENFVEQVIEAQEIERRRLAGDIHDGISQRLVTLSYRLDAAVRAIGDPEVVSEQLGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RELVALTLGEARAAISGLRPPVLDDLGLAGGLASLARSIPQVDIDVDLAERRLPDHIELA
HHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHCCCCEEECCHHHHCCCHHHHHH
LYRIAQECLQNVVKHSGAATARLTFGVADDATGQTARLEIIDDGVGFDTFEHPLGGDEMG
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
GYGLLSMAERAEIVGGRLNIRSRPGAGTAVTATIPLPSVAD
CCHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]