BacMap

Definition	Mycobacterium sp. MCS chromosome, complete genome.
Accession	NC_008146
Length	5,705,448

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The map label for this gene is yusZ [H]

Identifier: 108798011

GI number: 108798011

Start: 1135118

End: 1135861

Strand: Direct

Name: yusZ [H]

Synonym: Mmcs_1038

Alternate gene names: 108798011

Gene position: 1135118-1135861 (Clockwise)

Preceding gene: 108798010

Following gene: 108798012

Centisome position: 19.9

GC content: 68.28

Gene sequence:

>744_bases
ATGAAAACAGTGCTCGTCACCGGTTGCTCCTCGGGCTACGGACTCGCGACCGCGCAGCGGTTCCACCGCGAGGGCTGGAA
CGTCGTCGCCACCATGCGCACACCCCGCGACGAGGTGTTGGCGCCGGGGGAGCGGCTGACCGTGCTGCCCCTCGACGTGA
CGGACCCGGCAAGCATCGCCGACGCCGTCGCCTCGGCCGGTCCCATCGATGTGCTCGTCAACAACGCGGGCATCGGAGCC
GTCGGCGCGTTCGAGGCCATGCCGATGTCGCTCGTCCGGGAGTTGTTCGAGACCAACACCTTCGGGGTGATGGCGATGAC
CCAGGCGGTGATTCCCCAGATGCGCGAGCGGCGCTCGGGTGTCGTGGTCAACGTGACGTCGTCGGTGACGCTGACGGCGA
TGCCGCTGGCGGCCGCCTACACCGCGAGCAAGATGGCCGTCGAAGGGTTCACCGCTTCGCTGGCGTTGGAGCTCGAATTC
TTCGGTGTGCGAGCCAAACTCGTGCAGCCTGGCTACGGACCGTCGACGCAGTTCGCCGCCAACGGCAGCGATCGCATGGA
CGGGGTGATCCCCGAGTCGTATGCAGCGTTCGCGGAGCCGGTCTTCGCCGCATTCAGCCAACCCGGTCCGGTGACCACTG
CGGAGGACGTGGCGACGGTGGTGCTGCGCGCCGCCGGTGACACGTCGGGACAGTTGCGGTTTCCGGCCGGGGCGGATGCG
GTGGCGTTGGCTGCTTCGGCCTAA

Upstream 100 bases:

>100_bases
AGCCGTTCTGCCTCCCGGCATGTGCCGTCAGACGATCGGTGAAGGATCCCGGACGGCCGGCTATTCCCGGGCGGGCTCGG
GCGACCATAGCGTTTCACGT

Downstream 100 bases:

>100_bases
TAGCTTGTCGGGTGTGAACCCTGACGACGGGTTGGGGCCGGTCGAGATGCTGGTGTCTCTGCTGCGACCGAAGACGGTCG
AGTCGAAGATCATCAGCGGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKTVLVTGCSSGYGLATAQRFHREGWNVVATMRTPRDEVLAPGERLTVLPLDVTDPASIADAVASAGPIDVLVNNAGIGA
VGAFEAMPMSLVRELFETNTFGVMAMTQAVIPQMRERRSGVVVNVTSSVTLTAMPLAAAYTASKMAVEGFTASLALELEF
FGVRAKLVQPGYGPSTQFAANGSDRMDGVIPESYAAFAEPVFAAFSQPGPVTTAEDVATVVLRAAGDTSGQLRFPAGADA
VALAASA

Sequences:

>Translated_247_residues
MKTVLVTGCSSGYGLATAQRFHREGWNVVATMRTPRDEVLAPGERLTVLPLDVTDPASIADAVASAGPIDVLVNNAGIGA
VGAFEAMPMSLVRELFETNTFGVMAMTQAVIPQMRERRSGVVVNVTSSVTLTAMPLAAAYTASKMAVEGFTASLALELEF
FGVRAKLVQPGYGPSTQFAANGSDRMDGVIPESYAAFAEPVFAAFSQPGPVTTAEDVATVVLRAAGDTSGQLRFPAGADA
VALAASA
>Mature_247_residues
MKTVLVTGCSSGYGLATAQRFHREGWNVVATMRTPRDEVLAPGERLTVLPLDVTDPASIADAVASAGPIDVLVNNAGIGA
VGAFEAMPMSLVRELFETNTFGVMAMTQAVIPQMRERRSGVVVNVTSSVTLTAMPLAAAYTASKMAVEGFTASLALELEF
FGVRAKLVQPGYGPSTQFAANGSDRMDGVIPESYAAFAEPVFAAFSQPGPVTTAEDVATVVLRAAGDTSGQLRFPAGADA
VALAASA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=181, Percent_Identity=41.9889502762431, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI223718074, Length=182, Percent_Identity=37.9120879120879, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI40548397, Length=181, Percent_Identity=33.1491712707182, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI214010158, Length=181, Percent_Identity=33.1491712707182, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI214010156, Length=181, Percent_Identity=33.1491712707182, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI22758144, Length=181, Percent_Identity=33.1491712707182, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI20149619, Length=185, Percent_Identity=30.2702702702703, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7706318, Length=183, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI150247226, Length=264, Percent_Identity=29.5454545454545, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI119392083, Length=186, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=30.8510638297872, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=30.8510638297872, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=30.8510638297872, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI22507405, Length=268, Percent_Identity=29.8507462686567, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI19743808, Length=181, Percent_Identity=33.1491712707182, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI50726952, Length=180, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI157739938, Length=186, Percent_Identity=27.9569892473118, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI4503817, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4504503, Length=182, Percent_Identity=31.8681318681319, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=30.6451612903226, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI32483357, Length=184, Percent_Identity=34.7826086956522, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87082100, Length=182, Percent_Identity=39.010989010989, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786701, Length=175, Percent_Identity=33.1428571428571, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787820, Length=204, Percent_Identity=34.8039215686275, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787335, Length=201, Percent_Identity=31.8407960199005, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367365, Length=188, Percent_Identity=34.0425531914894, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790717, Length=181, Percent_Identity=30.939226519337, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=182, Percent_Identity=29.1208791208791, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=175, Percent_Identity=33.1428571428571, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367175, Length=225, Percent_Identity=27.5555555555556, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789208, Length=182, Percent_Identity=29.6703296703297, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787905, Length=136, Percent_Identity=31.6176470588235, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082160, Length=180, Percent_Identity=25, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI72000259, Length=241, Percent_Identity=33.195020746888, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=189, Percent_Identity=31.7460317460317, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=188, Percent_Identity=33.5106382978723, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=184, Percent_Identity=30.9782608695652, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=184, Percent_Identity=29.8913043478261, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.5882352941176, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=30.327868852459, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=188, Percent_Identity=31.9148936170213, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=193, Percent_Identity=29.5336787564767, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557780, Length=206, Percent_Identity=29.6116504854369, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=215, Percent_Identity=26.5116279069767, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=183, Percent_Identity=29.5081967213115, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=197, Percent_Identity=31.9796954314721, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=187, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193210355, Length=212, Percent_Identity=28.7735849056604, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=186, Percent_Identity=31.7204301075269, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=191, Percent_Identity=30.8900523560209, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=188, Percent_Identity=29.7872340425532, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=190, Percent_Identity=32.1052631578947, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=188, Percent_Identity=34.5744680851064, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571526, Length=223, Percent_Identity=34.9775784753363, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=34.8178137651822, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21358495, Length=239, Percent_Identity=32.6359832635983, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644339, Length=223, Percent_Identity=33.1838565022422, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=223, Percent_Identity=32.2869955156951, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24651139, Length=188, Percent_Identity=30.8510638297872, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24643142, Length=186, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639444, Length=183, Percent_Identity=32.7868852459016, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356301, Length=184, Percent_Identity=28.804347826087, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640442, Length=184, Percent_Identity=29.3478260869565, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24584744, Length=181, Percent_Identity=29.8342541436464, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584748, Length=212, Percent_Identity=27.8301886792453, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007236, Length=188, Percent_Identity=33.5106382978723, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574402, Length=181, Percent_Identity=29.8342541436464, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161076933, Length=210, Percent_Identity=27.1428571428571, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=32.967032967033, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=181, Percent_Identity=27.0718232044199, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644337, Length=136, Percent_Identity=36.0294117647059, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17737361, Length=196, Percent_Identity=31.1224489795918, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25534; Mature: 25534

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLVTGCSSGYGLATAQRFHREGWNVVATMRTPRDEVLAPGERLTVLPLDVTDPASIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCHHHHCCCCCEEEEEEECCCCCHHHH
DAVASAGPIDVLVNNAGIGAVGAFEAMPMSLVRELFETNTFGVMAMTQAVIPQMRERRSG
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
VVVNVTSSVTLTAMPLAAAYTASKMAVEGFTASLALELEFFGVRAKLVQPGYGPSTQFAA
EEEEEECCEEEEEHHHHHHHHHHHHHHCCCEEEEEEEEEEECEEEEEECCCCCCCCCEEC
NGSDRMDGVIPESYAAFAEPVFAAFSQPGPVTTAEDVATVVLRAAGDTSGQLRFPAGADA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCEEECCCCCCC
VALAASA
EEEEECC
>Mature Secondary Structure
MKTVLVTGCSSGYGLATAQRFHREGWNVVATMRTPRDEVLAPGERLTVLPLDVTDPASIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCHHHHCCCCCEEEEEEECCCCCHHHH
DAVASAGPIDVLVNNAGIGAVGAFEAMPMSLVRELFETNTFGVMAMTQAVIPQMRERRSG
HHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
VVVNVTSSVTLTAMPLAAAYTASKMAVEGFTASLALELEFFGVRAKLVQPGYGPSTQFAA
EEEEEECCEEEEEHHHHHHHHHHHHHHCCCEEEEEEEEEEECEEEEEECCCCCCCCCEEC
NGSDRMDGVIPESYAAFAEPVFAAFSQPGPVTTAEDVATVVLRAAGDTSGQLRFPAGADA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEECCCCCCEEECCCCCCC
VALAASA
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]