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The map label for this gene is recD [H]

Identifier: 108797872

GI number: 108797872

Start: 992176

End: 993918

Strand: Reverse

Name: recD [H]

Synonym: Mmcs_0897

Alternate gene names: 108797872

Gene position: 993918-992176 (Counterclockwise)

Preceding gene: 108797873

Following gene: 108797871

Centisome position: 17.42

GC content: 72.4

Gene sequence:

>1743_bases
ATGAGCGTCGGCGCCCTCGCCGTCACCGGGTTGCTGCGCGCCTTCACCGACGCGGAGGTGTTCGAACCCGCCGATGTGCA
CGTCGCGCGCCGGCTCACCGACATGGCGAAGGAACCCGACGAATCCGTCGCGCTCGCCGTGGCATTCGCGGTGCGCGCCC
TGCGCAACGGGTCGGTCTGTGTGGACCTGAGGGCCGTCGCGGACCAGGTCGGATTGCCCGACCTGCCCTGGCGCGACCCC
GAGGCGTGGCTGACCGCGGTGCGGGCCAGTCCGCTGACCGGGACGCCGCCGGTGCTGAGGCTCTACTCCGGCTCCTCGGG
TGACCTGCTCTACCTCGACCGTTACTGGCGCGAAGAACAACAGGTGTGCGACGACGTGCTCGCGCTGCTGGAATCGTCGC
CGCCGGGTGCGGTGCCCGGACTCGACCGCCTGTTTCCCACCGCCGACTTCCCCGAGCAACGCGTCGCCGCGGAAATCGCG
CTGTCGCAATCACTTACGGTGCTGACCGGCGGCCCCGGCACCGGTAAGACGACGACGGTGGCGCGGCTGTTGGCGCTGCT
CGCCGAACAGGCCTCGCTGCAGAACCGGCCACCGCTGCGCATCGCGCTGGCCGCCCCGACCGGTAAGGCCGCGGCCCGCC
TGCTCGAGGCCGTACACCTGCAGATCGCCGGACTCGACGCCGTCGACCGTGACCGTCTGCCCGAACTGACCGCCTCGACA
CTGCACCGGCTGCTGCAGCGGCGCCGGGACAACGCGTCGCGGTTCCGCCACCACCGGGAGAACCGGCTGCCGCACGACGT
GATCGTCGTCGACGAGACGTCAATGGTGTCGCTGACGCTGATGGCCCGGCTCCTCGAAGCCGTGCGGCCCGACAGCCGGT
TGCTGCTGGTGGGCGACGCCGACCAGTTGGCGTCGGTGGAGGCCGGGGCCGTGCTGGCCGACCTCGTCGACGGGCTGGGC
GCACGCGACGACGTGCGCATCGCCCGGCTGGTCACCTCGCACCGCTTCGGCGCGCCGATCGGGGCGCTGGCGAAGGCGAT
CCGCGACGGCGAGACCGACACCGTGATCGGGCTGCTGCGCGACGGCGGCCCCGACATCGAATGGTTCGACACCGACAACC
CGGCCGACCGGTTGCGCAAAGTGCTTGTGCCGCATGCGCTCCGGCTGCGGGAGGCGGCCATCCTCGGGGATGGGCCGGCA
GCGTTGGCCACGCTCGACGAACACCGTCTGCTGTGCGCGCACCGGCGCGGACCGTACGGCGTGCGGCACTGGAACCGACA
GGTCGAACGCTGGCTCACCGACGCGACCGGCGAGCCGATCTGGTCGGACTGGTACGCCGGGCGGCCGCTGCTGGTCACCG
CCAACGATTACGGGCTGCGGCTCTACAACGGCGACACCGGTGTGACGGTCGTGCGCGGCGACGGGCTCACGGCGGTGGTG
GGCTCGGGCGCCGGGCCGGTCGAGTTCTCGACCAGCCGGCTCGCCGACGTCGAGACCGTGCACGCGATGACCATCCACAA
GAGCCAGGGCAGCCAGGCCCGGGAGGTGACCGTGCTGCTCCCCGACGAGGAGTCGCGGCTGCTGACCCGCGAGCTGTTCT
ACACCGCGGTCACCCGCGCGAAGGCGAAGGTGCGGGTGGTCGGCTCGGAGGCGGCGGTGCGGGCGGCGATCGAGCGGCGT
GTGGTGCGGGCGTCGGGGCTGGCGCAGCGGCTCGGCGGGTCGGGGCGCACAGCGAGCACGTAA

Upstream 100 bases:

>100_bases
ACCGGTCGTTCAGCGATTTCCTGCGCTCGCACGCCGATCTGGTCGAACTCGACGAGAGCTCGACCACCCGCTTGGTGCGC
CTGCGGCTCCCCGCCGACTC

Downstream 100 bases:

>100_bases
CCGTGCGCAAACTCGATATCGCCCGCGCTATCAGATAGCGCCGGCGATATCGCTTTTCGGCAGCACCACACACCTCCTCC
GCGCCGCGTGTGCGCTCCCC

Product: DNA helicase/exodeoxyribonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MSVGALAVTGLLRAFTDAEVFEPADVHVARRLTDMAKEPDESVALAVAFAVRALRNGSVCVDLRAVADQVGLPDLPWRDP
EAWLTAVRASPLTGTPPVLRLYSGSSGDLLYLDRYWREEQQVCDDVLALLESSPPGAVPGLDRLFPTADFPEQRVAAEIA
LSQSLTVLTGGPGTGKTTTVARLLALLAEQASLQNRPPLRIALAAPTGKAAARLLEAVHLQIAGLDAVDRDRLPELTAST
LHRLLQRRRDNASRFRHHRENRLPHDVIVVDETSMVSLTLMARLLEAVRPDSRLLLVGDADQLASVEAGAVLADLVDGLG
ARDDVRIARLVTSHRFGAPIGALAKAIRDGETDTVIGLLRDGGPDIEWFDTDNPADRLRKVLVPHALRLREAAILGDGPA
ALATLDEHRLLCAHRRGPYGVRHWNRQVERWLTDATGEPIWSDWYAGRPLLVTANDYGLRLYNGDTGVTVVRGDGLTAVV
GSGAGPVEFSTSRLADVETVHAMTIHKSQGSQAREVTVLLPDEESRLLTRELFYTAVTRAKAKVRVVGSEAAVRAAIERR
VVRASGLAQRLGGSGRTAST

Sequences:

>Translated_580_residues
MSVGALAVTGLLRAFTDAEVFEPADVHVARRLTDMAKEPDESVALAVAFAVRALRNGSVCVDLRAVADQVGLPDLPWRDP
EAWLTAVRASPLTGTPPVLRLYSGSSGDLLYLDRYWREEQQVCDDVLALLESSPPGAVPGLDRLFPTADFPEQRVAAEIA
LSQSLTVLTGGPGTGKTTTVARLLALLAEQASLQNRPPLRIALAAPTGKAAARLLEAVHLQIAGLDAVDRDRLPELTAST
LHRLLQRRRDNASRFRHHRENRLPHDVIVVDETSMVSLTLMARLLEAVRPDSRLLLVGDADQLASVEAGAVLADLVDGLG
ARDDVRIARLVTSHRFGAPIGALAKAIRDGETDTVIGLLRDGGPDIEWFDTDNPADRLRKVLVPHALRLREAAILGDGPA
ALATLDEHRLLCAHRRGPYGVRHWNRQVERWLTDATGEPIWSDWYAGRPLLVTANDYGLRLYNGDTGVTVVRGDGLTAVV
GSGAGPVEFSTSRLADVETVHAMTIHKSQGSQAREVTVLLPDEESRLLTRELFYTAVTRAKAKVRVVGSEAAVRAAIERR
VVRASGLAQRLGGSGRTAST
>Mature_579_residues
SVGALAVTGLLRAFTDAEVFEPADVHVARRLTDMAKEPDESVALAVAFAVRALRNGSVCVDLRAVADQVGLPDLPWRDPE
AWLTAVRASPLTGTPPVLRLYSGSSGDLLYLDRYWREEQQVCDDVLALLESSPPGAVPGLDRLFPTADFPEQRVAAEIAL
SQSLTVLTGGPGTGKTTTVARLLALLAEQASLQNRPPLRIALAAPTGKAAARLLEAVHLQIAGLDAVDRDRLPELTASTL
HRLLQRRRDNASRFRHHRENRLPHDVIVVDETSMVSLTLMARLLEAVRPDSRLLLVGDADQLASVEAGAVLADLVDGLGA
RDDVRIARLVTSHRFGAPIGALAKAIRDGETDTVIGLLRDGGPDIEWFDTDNPADRLRKVLVPHALRLREAAILGDGPAA
LATLDEHRLLCAHRRGPYGVRHWNRQVERWLTDATGEPIWSDWYAGRPLLVTANDYGLRLYNGDTGVTVVRGDGLTAVVG
SGAGPVEFSTSRLADVETVHAMTIHKSQGSQAREVTVLLPDEESRLLTRELFYTAVTRAKAKVRVVGSEAAVRAAIERRV
VRASGLAQRLGGSGRTAST

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=515, Percent_Identity=38.252427184466, Blast_Score=249, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 62615; Mature: 62484

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGALAVTGLLRAFTDAEVFEPADVHVARRLTDMAKEPDESVALAVAFAVRALRNGSVC
CCCHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
VDLRAVADQVGLPDLPWRDPEAWLTAVRASPLTGTPPVLRLYSGSSGDLLYLDRYWREEQ
EEHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHH
QVCDDVLALLESSPPGAVPGLDRLFPTADFPEQRVAAEIALSQSLTVLTGGPGTGKTTTV
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHH
ARLLALLAEQASLQNRPPLRIALAAPTGKAAARLLEAVHLQIAGLDAVDRDRLPELTAST
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHH
LHRLLQRRRDNASRFRHHRENRLPHDVIVVDETSMVSLTLMARLLEAVRPDSRLLLVGDA
HHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECH
DQLASVEAGAVLADLVDGLGARDDVRIARLVTSHRFGAPIGALAKAIRDGETDTVIGLLR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEE
DGGPDIEWFDTDNPADRLRKVLVPHALRLREAAILGDGPAALATLDEHRLLCAHRRGPYG
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCC
VRHWNRQVERWLTDATGEPIWSDWYAGRPLLVTANDYGLRLYNGDTGVTVVRGDGLTAVV
HHHHHHHHHHHHHHCCCCCCCCHHCCCCCEEEEECCCEEEEEECCCCEEEEECCCEEEEE
GSGAGPVEFSTSRLADVETVHAMTIHKSQGSQAREVTVLLPDEESRLLTRELFYTAVTRA
CCCCCCCCCCHHHHHHHHHEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHC
KAKVRVVGSEAAVRAAIERRVVRASGLAQRLGGSGRTAST
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVGALAVTGLLRAFTDAEVFEPADVHVARRLTDMAKEPDESVALAVAFAVRALRNGSVC
CCHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
VDLRAVADQVGLPDLPWRDPEAWLTAVRASPLTGTPPVLRLYSGSSGDLLYLDRYWREEQ
EEHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHH
QVCDDVLALLESSPPGAVPGLDRLFPTADFPEQRVAAEIALSQSLTVLTGGPGTGKTTTV
HHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHH
ARLLALLAEQASLQNRPPLRIALAAPTGKAAARLLEAVHLQIAGLDAVDRDRLPELTAST
HHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHH
LHRLLQRRRDNASRFRHHRENRLPHDVIVVDETSMVSLTLMARLLEAVRPDSRLLLVGDA
HHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECH
DQLASVEAGAVLADLVDGLGARDDVRIARLVTSHRFGAPIGALAKAIRDGETDTVIGLLR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEE
DGGPDIEWFDTDNPADRLRKVLVPHALRLREAAILGDGPAALATLDEHRLLCAHRRGPYG
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCCC
VRHWNRQVERWLTDATGEPIWSDWYAGRPLLVTANDYGLRLYNGDTGVTVVRGDGLTAVV
HHHHHHHHHHHHHHCCCCCCCCHHCCCCCEEEEECCCEEEEEECCCCEEEEECCCEEEEE
GSGAGPVEFSTSRLADVETVHAMTIHKSQGSQAREVTVLLPDEESRLLTRELFYTAVTRA
CCCCCCCCCCHHHHHHHHHEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHC
KAKVRVVGSEAAVRAAIERRVVRASGLAQRLGGSGRTAST
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]