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The map label for this gene is frlC [C]

Identifier: 108797646

GI number: 108797646

Start: 726305

End: 727150

Strand: Direct

Name: frlC [C]

Synonym: Mmcs_0666

Alternate gene names: 108797646

Gene position: 726305-727150 (Clockwise)

Preceding gene: 108797645

Following gene: 108797647

Centisome position: 12.73

GC content: 71.16

Gene sequence:

>846_bases
GTGCGCCCCGCGATCAAGGTCGGTCTGTCGACGGCCTCGGTCTATCCGCTGAGGACCGAGGCCGCCTTCGAGTACGCCGC
CCGCCTCGGCTACGACGGCGTCGAACTGATGGTGTGGGCCGAAGCCGTCAGCCAGGACATCGACGCCGTGGCGCGGTTGT
CCGCTCAATACGGGGTGCCCGTGCTGTCGGTGCACGCGCCCTGCCTGCTGATCTCGCAACGGGTGTGGGGCGCCAACCCG
ATCCCCAAACTGGACCGCAGCGTGCGCGCCGCCGAACAGCTCGGCGCCCAGACCGTCGTCGTGCATCCGCCGTTCCGCTG
GCAGCGCCGCTACGCCGAGGGCTTCAGCGAGCAGGTCGCCGAGCTCGAGGCGGGCAGCGACGTGATGGTTGCGGTGGAGA
ACATGTTCCCGTTCCGGGCCGACCGGTTCTTCGGCGCCGGCCAGACGTCGATCGAGCGGATGCGCAAACGCGGCGGCAGG
CCCGGACCGGGTATCTCGGCGTTCGCCCCCTCGTACGACCCGCTGGACGGCGATCACGCGCACTACACGCTCGACCTCTC
GCACACCGCGACGGCGGGCACCGACGCCATCGAGATGGCGCAGCGGATGGCAGACGGGCTCGTGCACCTGCACCTGGCCG
ACGGCAGCGGCGCGTCGGCCGACGAGCACCTGGTGCCCGGTCGCGGCACCCAGCCGACCGCCGAGGTGTGTCAGATGCTG
GCCAACGGCGACTTCAGCGGCCATGTCATCCTCGAGGTCACCACGTCCGGGGCGCGCACGGCCAACGAGCGCGAGGCACT
GCTGCGCGAATCGCTGCAGTACGCCCGGGCGCACCTGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGCAAGACCGAGGACATCGGCAGCACGCTGATCGCGGTGGCAGTGGGCGCACTGGTCACGCTGGGACCGCTGGCGTTGCT
CCAGTCCGGCTAGTCACCCT

Downstream 100 bases:

>100_bases
CCGACTGCGCGCCGACCCACGGAGGATCCACATGTCCGGTTCGACCCTGTTCACCGACGCGATGGCGCTCACCGCGCTGG
GCGAGGGCCGGTACCGCGGT

Product: xylose isomerase-like TIM barrel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRPAIKVGLSTASVYPLRTEAAFEYAARLGYDGVELMVWAEAVSQDIDAVARLSAQYGVPVLSVHAPCLLISQRVWGANP
IPKLDRSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSEQVAELEAGSDVMVAVENMFPFRADRFFGAGQTSIERMRKRGGR
PGPGISAFAPSYDPLDGDHAHYTLDLSHTATAGTDAIEMAQRMADGLVHLHLADGSGASADEHLVPGRGTQPTAEVCQML
ANGDFSGHVILEVTTSGARTANEREALLRESLQYARAHLLR

Sequences:

>Translated_281_residues
MRPAIKVGLSTASVYPLRTEAAFEYAARLGYDGVELMVWAEAVSQDIDAVARLSAQYGVPVLSVHAPCLLISQRVWGANP
IPKLDRSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSEQVAELEAGSDVMVAVENMFPFRADRFFGAGQTSIERMRKRGGR
PGPGISAFAPSYDPLDGDHAHYTLDLSHTATAGTDAIEMAQRMADGLVHLHLADGSGASADEHLVPGRGTQPTAEVCQML
ANGDFSGHVILEVTTSGARTANEREALLRESLQYARAHLLR
>Mature_281_residues
MRPAIKVGLSTASVYPLRTEAAFEYAARLGYDGVELMVWAEAVSQDIDAVARLSAQYGVPVLSVHAPCLLISQRVWGANP
IPKLDRSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSEQVAELEAGSDVMVAVENMFPFRADRFFGAGQTSIERMRKRGGR
PGPGISAFAPSYDPLDGDHAHYTLDLSHTATAGTDAIEMAQRMADGLVHLHLADGSGASADEHLVPGRGTQPTAEVCQML
ANGDFSGHVILEVTTSGARTANEREALLRESLQYARAHLLR

Specific function: Not Clear, May Be Involved In An Isomerization Step. [C]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML2432 and S.coelicolor SCO3347 [H]

Homologues:

None

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: NA

Molecular weight: Translated: 30421; Mature: 30421

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAIKVGLSTASVYPLRTEAAFEYAARLGYDGVELMVWAEAVSQDIDAVARLSAQYGVP
CCCCEEECCCCCEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLSVHAPCLLISQRVWGANPIPKLDRSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSEQVA
EEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
ELEAGSDVMVAVENMFPFRADRFFGAGQTSIERMRKRGGRPGPGISAFAPSYDPLDGDHA
HHCCCCCEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
HYTLDLSHTATAGTDAIEMAQRMADGLVHLHLADGSGASADEHLVPGRGTQPTAEVCQML
EEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
ANGDFSGHVILEVTTSGARTANEREALLRESLQYARAHLLR
HCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPAIKVGLSTASVYPLRTEAAFEYAARLGYDGVELMVWAEAVSQDIDAVARLSAQYGVP
CCCCEEECCCCCEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
VLSVHAPCLLISQRVWGANPIPKLDRSVRAAEQLGAQTVVVHPPFRWQRRYAEGFSEQVA
EEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
ELEAGSDVMVAVENMFPFRADRFFGAGQTSIERMRKRGGRPGPGISAFAPSYDPLDGDHA
HHCCCCCEEEEEECCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
HYTLDLSHTATAGTDAIEMAQRMADGLVHLHLADGSGASADEHLVPGRGTQPTAEVCQML
EEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHH
ANGDFSGHVILEVTTSGARTANEREALLRESLQYARAHLLR
HCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]