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The map label for this gene is yafV [C]

Identifier: 108797628

GI number: 108797628

Start: 709481

End: 710308

Strand: Reverse

Name: yafV [C]

Synonym: Mmcs_0648

Alternate gene names: 108797628

Gene position: 710308-709481 (Counterclockwise)

Preceding gene: 108797630

Following gene: 108797627

Centisome position: 12.45

GC content: 72.22

Gene sequence:

>828_bases
ATGTCCGGAGCCATGCGGATCGCCTGCGCACAGATCGCCGCGGGCACCGACCCGGCGGCCAACCTCGAGGTGCTCGAGGA
CCACACCGGCCGCGCCGTCGACGCCGGTGCGCAACTGGTGCTGTTCCCCGAGGCGACGATGTGCCGGTTCGGGGTGCCGC
TGGCGCCGGTCGCCGAACCGCTCGACGGGCCGTGGGCGTCGGCGGTGCGGTCGATCGCCGAACGGGCCGGCGTCACCGTC
GTCGCCGGCATGTTCACCCCCAGCGGCGACGGTCGCGTCCTCAACACGTTGATCGCGACCGGCGGCGGAGTCGACACCCA
CTACCACAAGATCCACCTCTACGACGCGTTCGGCTTTCGCGAATCCCGAACGGTCGCACCGGGTTCGGAGCCCGCCACGA
TCACGGTCGCGGGTGTCGAGGTCGGTCTCACGACGTGTTACGACATCCGCTTCCCGGAGCTCTACGTCGAGCTGGCGCGC
CGCGGCGCCCAGCTGATCACCGTCCACGCCTCGTGGGGTGCGGGGCCCGGCAAGCTCGACCAGTGGACCCTGCTGGCGCG
GGCGCGGGCGCTGGACACCACCGGCTACCTCGCCGCCGTCGACCAGGCCTATCCCGGCGACGAGGTGGCTGCCTCCGGAC
CGACCGGGATCGGCGGCAGCCTGGTCGCCTCGGCGACCGGAGAGGTGGTGGTCAGCGCGGGTGCGGACCCGCAGCTGATG
GTCGCCGACCTCGACCTCGACGCGGCGCGCGAGGTGCGCGAGACCATTGCGGTGCTGAACAACCGCGCGGAGGTCGACTC
ACCCGGTAGGGCAGAATCGCGGGCGTGA

Upstream 100 bases:

>100_bases
CGAAGAGCACCATCGGCCCAGACAAACCCCGCGCGGTTACAGCGGTTCGCGAGCGGGGTTAAGGGCGTGTTGCGAACGAC
GGCGGCCGTAGGCTTGGCAC

Downstream 100 bases:

>100_bases
CTGATCCCTGGGCCCGTCCGGCCGACCAGCAGCCAGTCCCGCCTCCCCCGCCGTTCCCGCAGGGTGCGCCGCCGTCGGCG
CCCGGCCCGGGAGCGGAACC

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSGAMRIACAQIAAGTDPAANLEVLEDHTGRAVDAGAQLVLFPEATMCRFGVPLAPVAEPLDGPWASAVRSIAERAGVTV
VAGMFTPSGDGRVLNTLIATGGGVDTHYHKIHLYDAFGFRESRTVAPGSEPATITVAGVEVGLTTCYDIRFPELYVELAR
RGAQLITVHASWGAGPGKLDQWTLLARARALDTTGYLAAVDQAYPGDEVAASGPTGIGGSLVASATGEVVVSAGADPQLM
VADLDLDAAREVRETIAVLNNRAEVDSPGRAESRA

Sequences:

>Translated_275_residues
MSGAMRIACAQIAAGTDPAANLEVLEDHTGRAVDAGAQLVLFPEATMCRFGVPLAPVAEPLDGPWASAVRSIAERAGVTV
VAGMFTPSGDGRVLNTLIATGGGVDTHYHKIHLYDAFGFRESRTVAPGSEPATITVAGVEVGLTTCYDIRFPELYVELAR
RGAQLITVHASWGAGPGKLDQWTLLARARALDTTGYLAAVDQAYPGDEVAASGPTGIGGSLVASATGEVVVSAGADPQLM
VADLDLDAAREVRETIAVLNNRAEVDSPGRAESRA
>Mature_274_residues
SGAMRIACAQIAAGTDPAANLEVLEDHTGRAVDAGAQLVLFPEATMCRFGVPLAPVAEPLDGPWASAVRSIAERAGVTVV
AGMFTPSGDGRVLNTLIATGGGVDTHYHKIHLYDAFGFRESRTVAPGSEPATITVAGVEVGLTTCYDIRFPELYVELARR
GAQLITVHASWGAGPGKLDQWTLLARARALDTTGYLAAVDQAYPGDEVAASGPTGIGGSLVASATGEVVVSAGADPQLMV
ADLDLDAAREVRETIAVLNNRAEVDSPGRAESRA

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=269, Percent_Identity=29.7397769516729, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI297632350, Length=273, Percent_Identity=29.6703296703297, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI297632348, Length=273, Percent_Identity=29.6703296703297, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=29.6703296703297, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17556280, Length=280, Percent_Identity=27.5, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322335, Length=304, Percent_Identity=27.3026315789474, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323383, Length=282, Percent_Identity=27.6595744680851, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355835, Length=273, Percent_Identity=28.2051282051282, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17933642, Length=270, Percent_Identity=27.7777777777778, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28408; Mature: 28277

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAMRIACAQIAAGTDPAANLEVLEDHTGRAVDAGAQLVLFPEATMCRFGVPLAPVAEP
CCCCCEEEEHHHHCCCCCCCCEEEEECCCCCEECCCCEEEEECCCHHHHCCCCCCCCCCC
LDGPWASAVRSIAERAGVTVVAGMFTPSGDGRVLNTLIATGGGVDTHYHKIHLYDAFGFR
CCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHCCCCCCCEEEEEEEEEECCCC
ESRTVAPGSEPATITVAGVEVGLTTCYDIRFPELYVELARRGAQLITVHASWGAGPGKLD
CCCCCCCCCCCCEEEEEEEEECEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC
QWTLLARARALDTTGYLAAVDQAYPGDEVAASGPTGIGGSLVASATGEVVVSAGADPQLM
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCEEE
VADLDLDAAREVRETIAVLNNRAEVDSPGRAESRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SGAMRIACAQIAAGTDPAANLEVLEDHTGRAVDAGAQLVLFPEATMCRFGVPLAPVAEP
CCCCEEEEHHHHCCCCCCCCEEEEECCCCCEECCCCEEEEECCCHHHHCCCCCCCCCCC
LDGPWASAVRSIAERAGVTVVAGMFTPSGDGRVLNTLIATGGGVDTHYHKIHLYDAFGFR
CCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEHHHHCCCCCCCEEEEEEEEEECCCC
ESRTVAPGSEPATITVAGVEVGLTTCYDIRFPELYVELARRGAQLITVHASWGAGPGKLD
CCCCCCCCCCCCEEEEEEEEECEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC
QWTLLARARALDTTGYLAAVDQAYPGDEVAASGPTGIGGSLVASATGEVVVSAGADPQLM
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCEEE
VADLDLDAAREVRETIAVLNNRAEVDSPGRAESRA
EEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]