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The map label for this gene is ycdF [H]

Identifier: 108797597

GI number: 108797597

Start: 679872

End: 680726

Strand: Reverse

Name: ycdF [H]

Synonym: Mmcs_0617

Alternate gene names: 108797597

Gene position: 680726-679872 (Counterclockwise)

Preceding gene: 108797598

Following gene: 108797595

Centisome position: 11.93

GC content: 64.09

Gene sequence:

>855_bases
ATGTCAACTGATTTCGACCGCAGAGAGCGCAAGGCCTTCGACCTGACCGGCAAGGTCGTCGTCGTGGTGGGAGCGGGACA
GAGCCCGGGCCCCGGCATGGGCAACGGGCGCGCGATCTCGCTCCTGGCGGCACGTCACGGCGCGGAGGTCGTGGCGGTCG
ACCTGAACCCGGCCGCGGTGAAAGAGACCGTCGAGATGATCCTCGCCGAGGGCGGCAAGGCCTACGCCATCGAGGCGGAC
GTCGCCGAGAAGGACGATTGCCGGCGAATCTTCGACACGGCGATGGCCACCAGCGGTCGTGTCGACGGCATGGTCTACAG
CGTCGCGACCAATCCGCCGTTCGACATCGAGACGAACTCGATGACCGTCGAGAACTTCAACCGCGGCATCAACGTCAACA
TGCTCGGGTGCTACTACTGCAATCTGTATGCCGCACAGTGCATGGAGCGCAACGACGGGGACTCCACCGGCAGCATCGTC
AACCTCTCGTCGATCGCGAGCGTGAAGAACGAACTCGGTCTGAACATCGGCATCATGCCCTATGCGCTGGGCAAGAGCGG
TCTGAACCAGATCACCGAACTGACCGCCGTGCAGTACGCGGCGGCCGGCATCCGCGCCAACACGTTGATGCTGGGCCCCA
TCGATTCCGTTCTGGCGAAGAATGATTCGCAGTCGCTCTTCGGATTGGACGCCGAGGAGGCGACCCAGCGGCACAACGAG
GTCGTCAAGCTCAAGATGGGCCGCGGCAGCGTTTGGGAGAGCGCCTACGCCGCCGTGTATCTGCTCGCCGACGAATCGCG
GTTCATGACCGGACAGCAGATCCGGCTCGATGGTGGCGCCACCTTGGTGCGGTGA

Upstream 100 bases:

>100_bases
GAAGCCACCGCCGACGGCATCCCGCCGGACCTCGAGGCCTCGGTGCGCGAGGCGGTCGACGGGTGTCCCGAACACGCCAT
CCACATCAAAGAGGAGAACC

Downstream 100 bases:

>100_bases
CCACCGCGAACTCCAACCCGTGCTGGTTCAACGTCACCGGCAGCGGTTCGTCCGGTGAGAGGTGTGGCATCGACGAAATT
CGGAAGTCCAACGCGCTCAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: GLCDH-II; GDH-II; General stress protein 74; GSP74 [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSTDFDRRERKAFDLTGKVVVVVGAGQSPGPGMGNGRAISLLAARHGAEVVAVDLNPAAVKETVEMILAEGGKAYAIEAD
VAEKDDCRRIFDTAMATSGRVDGMVYSVATNPPFDIETNSMTVENFNRGINVNMLGCYYCNLYAAQCMERNDGDSTGSIV
NLSSIASVKNELGLNIGIMPYALGKSGLNQITELTAVQYAAAGIRANTLMLGPIDSVLAKNDSQSLFGLDAEEATQRHNE
VVKLKMGRGSVWESAYAAVYLLADESRFMTGQQIRLDGGATLVR

Sequences:

>Translated_284_residues
MSTDFDRRERKAFDLTGKVVVVVGAGQSPGPGMGNGRAISLLAARHGAEVVAVDLNPAAVKETVEMILAEGGKAYAIEAD
VAEKDDCRRIFDTAMATSGRVDGMVYSVATNPPFDIETNSMTVENFNRGINVNMLGCYYCNLYAAQCMERNDGDSTGSIV
NLSSIASVKNELGLNIGIMPYALGKSGLNQITELTAVQYAAAGIRANTLMLGPIDSVLAKNDSQSLFGLDAEEATQRHNE
VVKLKMGRGSVWESAYAAVYLLADESRFMTGQQIRLDGGATLVR
>Mature_283_residues
STDFDRRERKAFDLTGKVVVVVGAGQSPGPGMGNGRAISLLAARHGAEVVAVDLNPAAVKETVEMILAEGGKAYAIEADV
AEKDDCRRIFDTAMATSGRVDGMVYSVATNPPFDIETNSMTVENFNRGINVNMLGCYYCNLYAAQCMERNDGDSTGSIVN
LSSIASVKNELGLNIGIMPYALGKSGLNQITELTAVQYAAAGIRANTLMLGPIDSVLAKNDSQSLFGLDAEEATQRHNEV
VKLKMGRGSVWESAYAAVYLLADESRFMTGQQIRLDGGATLVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=289, Percent_Identity=29.0657439446367, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI40254992, Length=256, Percent_Identity=28.125, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=25.609756097561, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=29.1828793774319, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082100, Length=269, Percent_Identity=26.7657992565056, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787905, Length=267, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789208, Length=271, Percent_Identity=27.3062730627306, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=278, Percent_Identity=26.978417266187, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=278, Percent_Identity=25.8992805755396, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=286, Percent_Identity=25.5244755244755, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=283, Percent_Identity=26.1484098939929, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=281, Percent_Identity=27.0462633451957, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=282, Percent_Identity=24.113475177305, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=267, Percent_Identity=25.8426966292135, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21357041, Length=267, Percent_Identity=30.3370786516854, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571526, Length=266, Percent_Identity=29.6992481203008, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644339, Length=275, Percent_Identity=28.3636363636364, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639444, Length=268, Percent_Identity=29.8507462686567, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 30305; Mature: 30174

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDFDRRERKAFDLTGKVVVVVGAGQSPGPGMGNGRAISLLAARHGAEVVAVDLNPAAV
CCCCCCCHHHHHEECCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEEECCHHHH
KETVEMILAEGGKAYAIEADVAEKDDCRRIFDTAMATSGRVDGMVYSVATNPPFDIETNS
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEECCC
MTVENFNRGINVNMLGCYYCNLYAAQCMERNDGDSTGSIVNLSSIASVKNELGLNIGIMP
EEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCEEEEEE
YALGKSGLNQITELTAVQYAAAGIRANTLMLGPIDSVLAKNDSQSLFGLDAEEATQRHNE
HHCCHHHHHHHHHHHHHHHHHCCCEECEEEECCHHHHHHCCCCCCEECCCHHHHHHHCCE
VVKLKMGRGSVWESAYAAVYLLADESRFMTGQQIRLDGGATLVR
EEEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCEEECC
>Mature Secondary Structure 
STDFDRRERKAFDLTGKVVVVVGAGQSPGPGMGNGRAISLLAARHGAEVVAVDLNPAAV
CCCCCCHHHHHEECCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEEEECCHHHH
KETVEMILAEGGKAYAIEADVAEKDDCRRIFDTAMATSGRVDGMVYSVATNPPFDIETNS
HHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEECCC
MTVENFNRGINVNMLGCYYCNLYAAQCMERNDGDSTGSIVNLSSIASVKNELGLNIGIMP
EEEECCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHCCEEEEEE
YALGKSGLNQITELTAVQYAAAGIRANTLMLGPIDSVLAKNDSQSLFGLDAEEATQRHNE
HHCCHHHHHHHHHHHHHHHHHCCCEECEEEECCHHHHHHCCCCCCEECCCHHHHHHHCCE
VVKLKMGRGSVWESAYAAVYLLADESRFMTGQQIRLDGGATLVR
EEEEEECCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9298659 [H]