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The map label for this gene is caiD [C]

Identifier: 108797595

GI number: 108797595

Start: 677756

End: 678658

Strand: Reverse

Name: caiD [C]

Synonym: Mmcs_0615

Alternate gene names: 108797595

Gene position: 678658-677756 (Counterclockwise)

Preceding gene: 108797597

Following gene: 108797589

Centisome position: 11.89

GC content: 68.88

Gene sequence:

>903_bases
ATGACGGAGTTCGAGACGCTGCTCTACCGCACCGACACCGACGCCGCCGTCGCGACGATCACCCTCAACCGGCCGGATCA
GCTGAACACGATCGTGCCGCCGATGCCCGACGAGATCGAGTCCGCGATCGGACTCGCCGAGCGGGATCCGCAGGTCAAGG
TCATCGTGTTGCGCGGCGCGGGCCGGGCGTTCTCGGGCGGCTACGACTTCGGGGGCGGATTCGCGCACTGGGACGAGTCG
ATGAACAGCGACGGCCGCTGGGACCCGGGCAAGGACTTCGCGTTCGTCACCGGCCGCGCCACCTCGCCGACCGGGAAGTT
CATGTCGATCTGGCGGGCGTCGAAACCCGTCATCGCGCAGGTGCACGGCTGGTGTGTCGGCGGGGCGAGCGACTACGCGC
TGTGCGCCGACATCGTGATCGCCAGCGACGACGCCGTCATCGGCACGCCGTACGCCCGGATGTGGGGTGCCTACCTGACC
GGGATGTGGCTCTACCGGCTCAGCCTGGCGAAGGTGAAGTGGCATTCGCTGACCGGTGAACCGCTGACCGGCGTCGAGGC
CGCCGCCGTCGAGTTGATCAACGAATCGGTGCCGTTCGAACGTCTCGAGGCGCGGGTGGCCGAGGTGGCCGGACGACTGG
CCCGGATTCCGTTGTCGCAGTTGCAGGCCCAGAAGCTGATCGTCAACCAGGCCTACGAGAACATGGGGCTGGCCTCCACG
CAGACCCTCGGCGGCATCCTCGACGGGCTGATGCGCAACACCCCGGAGGCGCTGGAGTTCATCGCGACGGCCGAGTCGCA
CGGCGTGCGCGCCGCGGTCGAACGGCGCGACGGTCCGTGGGGCGACTACAGCCAGGCTCCCCCACACCGGCGCCCCGATC
CGTCACACTCGATCGATCCCTGA

Upstream 100 bases:

>100_bases
GGTCGGCCAACGTCGCGGCGGCCCTCGCCCCGGTGAGTCGACGCCCACTCGCTCCCATGAACTGGCATTTCCCCGGCCGG
CACCCTGCCAAACTGCAGGT

Downstream 100 bases:

>100_bases
TCGCTCCGGTGGACGCCCCAGACCCCCGAGCAGCGAGACCACCACACCGACCGCCACCAGCGCCCCACCCGCGGCCAGCG
TCAGATTCAGCCAGTGGTGC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTEFETLLYRTDTDAAVATITLNRPDQLNTIVPPMPDEIESAIGLAERDPQVKVIVLRGAGRAFSGGYDFGGGFAHWDES
MNSDGRWDPGKDFAFVTGRATSPTGKFMSIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYARMWGAYLT
GMWLYRLSLAKVKWHSLTGEPLTGVEAAAVELINESVPFERLEARVAEVAGRLARIPLSQLQAQKLIVNQAYENMGLAST
QTLGGILDGLMRNTPEALEFIATAESHGVRAAVERRDGPWGDYSQAPPHRRPDPSHSIDP

Sequences:

>Translated_300_residues
MTEFETLLYRTDTDAAVATITLNRPDQLNTIVPPMPDEIESAIGLAERDPQVKVIVLRGAGRAFSGGYDFGGGFAHWDES
MNSDGRWDPGKDFAFVTGRATSPTGKFMSIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYARMWGAYLT
GMWLYRLSLAKVKWHSLTGEPLTGVEAAAVELINESVPFERLEARVAEVAGRLARIPLSQLQAQKLIVNQAYENMGLAST
QTLGGILDGLMRNTPEALEFIATAESHGVRAAVERRDGPWGDYSQAPPHRRPDPSHSIDP
>Mature_299_residues
TEFETLLYRTDTDAAVATITLNRPDQLNTIVPPMPDEIESAIGLAERDPQVKVIVLRGAGRAFSGGYDFGGGFAHWDESM
NSDGRWDPGKDFAFVTGRATSPTGKFMSIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYARMWGAYLTG
MWLYRLSLAKVKWHSLTGEPLTGVEAAAVELINESVPFERLEARVAEVAGRLARIPLSQLQAQKLIVNQAYENMGLASTQ
TLGGILDGLMRNTPEALEFIATAESHGVRAAVERRDGPWGDYSQAPPHRRPDPSHSIDP

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Escherichia coli, GI221142681, Length=271, Percent_Identity=27.3062730627306, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=224, Percent_Identity=29.0178571428571, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=211, Percent_Identity=29.3838862559242, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=132, Percent_Identity=30.3030303030303, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20129971, Length=224, Percent_Identity=27.2321428571429, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24653477, Length=224, Percent_Identity=27.2321428571429, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357171, Length=210, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650670, Length=266, Percent_Identity=24.4360902255639, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 32598; Mature: 32467

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFETLLYRTDTDAAVATITLNRPDQLNTIVPPMPDEIESAIGLAERDPQVKVIVLRGA
CCCHHEEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEECC
GRAFSGGYDFGGGFAHWDESMNSDGRWDPGKDFAFVTGRATSPTGKFMSIWRASKPVIAQ
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEE
VHGWCVGGASDYALCADIVIASDDAVIGTPYARMWGAYLTGMWLYRLSLAKVKWHSLTGE
ECCEEECCCCCHHEEEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
PLTGVEAAAVELINESVPFERLEARVAEVAGRLARIPLSQLQAQKLIVNQAYENMGLAST
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHH
QTLGGILDGLMRNTPEALEFIATAESHGVRAAVERRDGPWGDYSQAPPHRRPDPSHSIDP
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEFETLLYRTDTDAAVATITLNRPDQLNTIVPPMPDEIESAIGLAERDPQVKVIVLRGA
CCHHEEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEECC
GRAFSGGYDFGGGFAHWDESMNSDGRWDPGKDFAFVTGRATSPTGKFMSIWRASKPVIAQ
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEE
VHGWCVGGASDYALCADIVIASDDAVIGTPYARMWGAYLTGMWLYRLSLAKVKWHSLTGE
ECCEEECCCCCHHEEEEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
PLTGVEAAAVELINESVPFERLEARVAEVAGRLARIPLSQLQAQKLIVNQAYENMGLAST
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHH
QTLGGILDGLMRNTPEALEFIATAESHGVRAAVERRDGPWGDYSQAPPHRRPDPSHSIDP
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA