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The map label for this gene is 108797541

Identifier: 108797541

GI number: 108797541

Start: 621507

End: 622997

Strand: Reverse

Name: 108797541

Synonym: Mmcs_0561

Alternate gene names: NA

Gene position: 622997-621507 (Counterclockwise)

Preceding gene: 108797542

Following gene: 108797540

Centisome position: 10.92

GC content: 64.52

Gene sequence:

>1491_bases
ATGACTTCGGAGCAGTACGACGCGGTCATCGTGGGCGCCGGATTCGCCGGAATCGGTGCCGCGATTCAGCTCAAGCGAAT
GGGCTACGCGAACTTCGTCATCCTCGACCGCGAGGACGACCTCGGCGGCACCTGGTACGTCAACCACTACCCGGGCCTGG
CCGTCGACGTCCCCACCACCACCTACAGCTATTTCTTCGAGCCCAACCCGAAGTGGTCGCGGCTGTTCTCCACCGGTGCG
GAGATCAAGCAGTACGCCGACGAGGTGGCCGACAAGTACGACGTCCGTCGCCACATCCGCTTCAACACGGCCGTCGAGGG
CGCCCGCTGGGACGAAGAGGCGAAGCTCTGGCGCGTGGCGCTCGACGGCGGGGAGACGCTGAGCACCCGCTATCTCATCA
CCGCGACGGGGTTCCTCTCGCAACCGCGGACCCCCGACATTCCCGGCATCACCTCGTTCGAGGGCAAGGTCATCCACACC
ACCGACTGGGACGACAGCTTCGACCCGTCGGGCCGGCGGATCGCGATCATCGGCACCGGCGCCACCGCCGTTCAGCTGAT
CCCCGAACTGGCCAGGAACGCCGCCGACCTCACCGTCTACCAGCGCACCCCGATCTGGGTGGCGCCCAAGGTCGACATCC
GGTTCTCCGAGCGCACCAAACGGCTGTTCGCGCGGGTTCCGCTGCTCCAGCGCACCGTGCGGCTGATCACCGACACGATC
TACGAGGCGATGATCAACATCGGTGTCGTGCACTACAAGGTGCCGCTGTTCCGGCGCCTCAACATGTCGGCGATGGATCT
GTGCAAGATCAACCAGTTCGTGGCGATCCGCGACAAAGAGCTGCGGCGCAAGCTCACCCCCGACTACGACATCGGCTGCA
AGCGACCGACGTTCTCCAACAGCTACTTCCGCACGTTCACCAAACCGCACGTCCACCTGCAGGCCGACGGGATCGACCAT
GTCGAAGCCGACGGCATCGTCAACGCCGACGGCACCAAGACCGTCATCGACACGCTGGTGCTGGCCACCGGATTCGACCT
GTGGGAGGCCAACTTCCCGGCGATCGAGATCATCGGCCGCGGTGGCCGCAACCTCGGGAAGTGGTGGCGCGAAACGCGTT
TCCAGGCGTACCAGGGTGTGTCGATGCCGTATTTCCCGAACTACCTCAGCCTGGCCAGCCCGTACGCATTCCTGGGTCTG
AACTTCTTCAACACCATGGAGTACCAGATGCGGCTGATGGACCGGCTTTTCAGCGAGGTGCACCGGCGCGGCGCCACGAC
GTTCGAGGTGACCGAGGAGGCCAACACCCGTTACCTCGATCGGATGACGGAAGCGCTCGGCAGTTCCCTGTGGACGCTCG
GCAACTGCGCCTCGTCGCGGTCCTACTATTTCAACCCGAGCGGCGAACCGTCGCTGCTGCGCCCGATGTCGACGCGCGAC
GCCATCAAAGAGGCGTCCGAGTTCCCGCTCAGTGATTACCAGATTGCCTGA

Upstream 100 bases:

>100_bases
GTCGCAACCCTGAACCCGCCGCGCGCGGGTTCACTGAAGGGCTGACGCCGCCCAGGTCGGCGGCACGGGACCACTCCGAT
ACCTGGGGTACCGTCTACTC

Downstream 100 bases:

>100_bases
AAGAGGACCCTCTGTGCCGCAACAAGACAACCGTGCCGCCAAGCTGACCGGGCTGGCCATCGCCGGGACCGGACTGGCGC
ACTTCGTTCGCCCGCAGGTG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MTSEQYDAVIVGAGFAGIGAAIQLKRMGYANFVILDREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPKWSRLFSTGA
EIKQYADEVADKYDVRRHIRFNTAVEGARWDEEAKLWRVALDGGETLSTRYLITATGFLSQPRTPDIPGITSFEGKVIHT
TDWDDSFDPSGRRIAIIGTGATAVQLIPELARNAADLTVYQRTPIWVAPKVDIRFSERTKRLFARVPLLQRTVRLITDTI
YEAMINIGVVHYKVPLFRRLNMSAMDLCKINQFVAIRDKELRRKLTPDYDIGCKRPTFSNSYFRTFTKPHVHLQADGIDH
VEADGIVNADGTKTVIDTLVLATGFDLWEANFPAIEIIGRGGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPYAFLGL
NFFNTMEYQMRLMDRLFSEVHRRGATTFEVTEEANTRYLDRMTEALGSSLWTLGNCASSRSYYFNPSGEPSLLRPMSTRD
AIKEASEFPLSDYQIA

Sequences:

>Translated_496_residues
MTSEQYDAVIVGAGFAGIGAAIQLKRMGYANFVILDREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPKWSRLFSTGA
EIKQYADEVADKYDVRRHIRFNTAVEGARWDEEAKLWRVALDGGETLSTRYLITATGFLSQPRTPDIPGITSFEGKVIHT
TDWDDSFDPSGRRIAIIGTGATAVQLIPELARNAADLTVYQRTPIWVAPKVDIRFSERTKRLFARVPLLQRTVRLITDTI
YEAMINIGVVHYKVPLFRRLNMSAMDLCKINQFVAIRDKELRRKLTPDYDIGCKRPTFSNSYFRTFTKPHVHLQADGIDH
VEADGIVNADGTKTVIDTLVLATGFDLWEANFPAIEIIGRGGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPYAFLGL
NFFNTMEYQMRLMDRLFSEVHRRGATTFEVTEEANTRYLDRMTEALGSSLWTLGNCASSRSYYFNPSGEPSLLRPMSTRD
AIKEASEFPLSDYQIA
>Mature_495_residues
TSEQYDAVIVGAGFAGIGAAIQLKRMGYANFVILDREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPKWSRLFSTGAE
IKQYADEVADKYDVRRHIRFNTAVEGARWDEEAKLWRVALDGGETLSTRYLITATGFLSQPRTPDIPGITSFEGKVIHTT
DWDDSFDPSGRRIAIIGTGATAVQLIPELARNAADLTVYQRTPIWVAPKVDIRFSERTKRLFARVPLLQRTVRLITDTIY
EAMINIGVVHYKVPLFRRLNMSAMDLCKINQFVAIRDKELRRKLTPDYDIGCKRPTFSNSYFRTFTKPHVHLQADGIDHV
EADGIVNADGTKTVIDTLVLATGFDLWEANFPAIEIIGRGGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPYAFLGLN
FFNTMEYQMRLMDRLFSEVHRRGATTFEVTEEANTRYLDRMTEALGSSLWTLGNCASSRSYYFNPSGEPSLLRPMSTRDA
IKEASEFPLSDYQIA

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503759, Length=227, Percent_Identity=25.9911894273128, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25145785, Length=229, Percent_Identity=25.764192139738, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 56333; Mature: 56201

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSEQYDAVIVGAGFAGIGAAIQLKRMGYANFVILDREDDLGGTWYVNHYPGLAVDVPTT
CCCCCCCEEEEECCCHHCCCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCEEEECCCC
TYSYFFEPNPKWSRLFSTGAEIKQYADEVADKYDVRRHIRFNTAVEGARWDEEAKLWRVA
EEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEE
LDGGETLSTRYLITATGFLSQPRTPDIPGITSFEGKVIHTTDWDDSFDPSGRRIAIIGTG
ECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECC
ATAVQLIPELARNAADLTVYQRTPIWVAPKVDIRFSERTKRLFARVPLLQRTVRLITDTI
HHHHHHHHHHHCCCCCEEEEECCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
YEAMINIGVVHYKVPLFRRLNMSAMDLCKINQFVAIRDKELRRKLTPDYDIGCKRPTFSN
HHHHHHCCEEEEECHHHHHCCCCHHHHHHCCCEEEECCHHHHHHCCCCCCCCCCCCCCCC
SYFRTFTKPHVHLQADGIDHVEADGIVNADGTKTVIDTLVLATGFDLWEANFPAIEIIGR
CHHEEECCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHCCCCCEEEEEEC
GGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPYAFLGLNFFNTMEYQMRLMDRLFSEV
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HRRGATTFEVTEEANTRYLDRMTEALGSSLWTLGNCASSRSYYFNPSGEPSLLRPMSTRD
HHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHCCCCCHHH
AIKEASEFPLSDYQIA
HHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSEQYDAVIVGAGFAGIGAAIQLKRMGYANFVILDREDDLGGTWYVNHYPGLAVDVPTT
CCCCCCEEEEECCCHHCCCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCEEEECCCC
TYSYFFEPNPKWSRLFSTGAEIKQYADEVADKYDVRRHIRFNTAVEGARWDEEAKLWRVA
EEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEE
LDGGETLSTRYLITATGFLSQPRTPDIPGITSFEGKVIHTTDWDDSFDPSGRRIAIIGTG
ECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECC
ATAVQLIPELARNAADLTVYQRTPIWVAPKVDIRFSERTKRLFARVPLLQRTVRLITDTI
HHHHHHHHHHHCCCCCEEEEECCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
YEAMINIGVVHYKVPLFRRLNMSAMDLCKINQFVAIRDKELRRKLTPDYDIGCKRPTFSN
HHHHHHCCEEEEECHHHHHCCCCHHHHHHCCCEEEECCHHHHHHCCCCCCCCCCCCCCCC
SYFRTFTKPHVHLQADGIDHVEADGIVNADGTKTVIDTLVLATGFDLWEANFPAIEIIGR
CHHEEECCCEEEEEECCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHCCCCCEEEEEEC
GGRNLGKWWRETRFQAYQGVSMPYFPNYLSLASPYAFLGLNFFNTMEYQMRLMDRLFSEV
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HRRGATTFEVTEEANTRYLDRMTEALGSSLWTLGNCASSRSYYFNPSGEPSLLRPMSTRD
HHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHCCCCCHHH
AIKEASEFPLSDYQIA
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]