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The map label for this gene is ppe42 [H]

Identifier: 108797399

GI number: 108797399

Start: 465006

End: 466031

Strand: Reverse

Name: ppe42 [H]

Synonym: Mmcs_0419

Alternate gene names: 108797399

Gene position: 466031-465006 (Counterclockwise)

Preceding gene: 108797400

Following gene: 108797398

Centisome position: 8.17

GC content: 65.69

Gene sequence:

>1026_bases
GTGCTCCTCGGCAACGGCAGCCGCCCGAATGGTGGATTGATGTCGCGGTTCGACGGGGCCTACATTCCGATCCTCGACGT
TTCGTTCATCGGTCCCACCCCGACGACCACGGCGGGGGCGACTCCGGGCGAGATCACGACCTATGACATCGCGCGCCAGT
ACGACCTCTTCGCCGACTTCCCGACCAATCCGCTGAATATCCTCGCCGTCGCCAACGCGTTCGCGGGTCAGCTCTTCGTG
CACCCTGACTACGGATCCGTCGACATGAGCCAAGCCGTGTTCCAGGGCACCTACGGCGACACGGCGTACTACCTGATCCC
GACCTATCCTCTGCCGCTCCTCATGCCGCTGACCTGGATTCCGGTCATCGGCCCCATTGCCGTCGACATGCTGGATCCCG
TACTGCGCGTCCTGGTGGAGGCTGGGTACGACCGCACCATCAATCCCGGTGTGCCGACACCGGCCAACTTCCTCTACTTG
CCCGACCCGGTGACCCTTGGTTCCAGCCTCCTTCACGCGATACCCACAGGACTGACATACGGGACGCAGGACATCCTCCA
TCTGCGCGAACCGGGGACACCGCCGCCCGGCGTGGCCGGGCAGGACGCGTACGGCATCGGCGGTCCGTCGGTGACCCTGC
CGAATCAGACGCCCCCGCCTGCACCCCCCGTCCAAACCGTAGCGGCGCCTTCGACGCCGAAAGTTCCTTCCGCCACGCCG
ACAACGGCGGTTCCTCTGTCTGACGGCGTGAACGATTCGGTGATTCCGTCGACGAGCCCGCCGGCGCCAAAGCAGCACAT
CGTCGACGAGCCGATCGGCGGGTCGTCTTCGAACGGGGCGGTCAAGAGGTCGGCATCAACGGCAGATGACGCTCCGGCGG
ATGCTTCGACCCAATCCCGCCCCAAGAGCTCAGGGACCACCGACCGCCCGAGCGGCGCCGGCAATTCCAACGGCAAGGGC
GGTTCCAGTTCCAGCAGCACCGGAAATTCGAACGGCAAGGGCAGTTCCAGCAGCACCGGCGACTGA

Upstream 100 bases:

>100_bases
CTTCGGCTACTCGCAGGGCACCCAGGTCGCGACGTTGTACAAGCGAGAATTCAACGAGTACTGAGCGAGCGACCCGACAG
CCGCGCCCGACGTCACCTTC

Downstream 100 bases:

>100_bases
GCGACGTCTCCCGCGATGTGGTTCTCACGCGAGTTGTGACCAGATCCGGGTATCCGAGTTTCGGCTAGGAGGTGTTCGGT
GAGACGACTGGTGGTGCGAG

Product: PE-PPE-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MLLGNGSRPNGGLMSRFDGAYIPILDVSFIGPTPTTTAGATPGEITTYDIARQYDLFADFPTNPLNILAVANAFAGQLFV
HPDYGSVDMSQAVFQGTYGDTAYYLIPTYPLPLLMPLTWIPVIGPIAVDMLDPVLRVLVEAGYDRTINPGVPTPANFLYL
PDPVTLGSSLLHAIPTGLTYGTQDILHLREPGTPPPGVAGQDAYGIGGPSVTLPNQTPPPAPPVQTVAAPSTPKVPSATP
TTAVPLSDGVNDSVIPSTSPPAPKQHIVDEPIGGSSSNGAVKRSASTADDAPADASTQSRPKSSGTTDRPSGAGNSNGKG
GSSSSSTGNSNGKGSSSSTGD

Sequences:

>Translated_341_residues
MLLGNGSRPNGGLMSRFDGAYIPILDVSFIGPTPTTTAGATPGEITTYDIARQYDLFADFPTNPLNILAVANAFAGQLFV
HPDYGSVDMSQAVFQGTYGDTAYYLIPTYPLPLLMPLTWIPVIGPIAVDMLDPVLRVLVEAGYDRTINPGVPTPANFLYL
PDPVTLGSSLLHAIPTGLTYGTQDILHLREPGTPPPGVAGQDAYGIGGPSVTLPNQTPPPAPPVQTVAAPSTPKVPSATP
TTAVPLSDGVNDSVIPSTSPPAPKQHIVDEPIGGSSSNGAVKRSASTADDAPADASTQSRPKSSGTTDRPSGAGNSNGKG
GSSSSSTGNSNGKGSSSSTGD
>Mature_341_residues
MLLGNGSRPNGGLMSRFDGAYIPILDVSFIGPTPTTTAGATPGEITTYDIARQYDLFADFPTNPLNILAVANAFAGQLFV
HPDYGSVDMSQAVFQGTYGDTAYYLIPTYPLPLLMPLTWIPVIGPIAVDMLDPVLRVLVEAGYDRTINPGVPTPANFLYL
PDPVTLGSSLLHAIPTGLTYGTQDILHLREPGTPPPGVAGQDAYGIGGPSVTLPNQTPPPAPPVQTVAAPSTPKVPSATP
TTAVPLSDGVNDSVIPSTSPPAPKQHIVDEPIGGSSSNGAVKRSASTADDAPADASTQSRPKSSGTTDRPSGAGNSNGKG
GSSSSSTGNSNGKGSSSSTGD

Specific function: Elicits a high humoral and a low T cell response. Could be involved in directing the host toward development of a more humoral type of immune response [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002989
- InterPro:   IPR013228
- InterPro:   IPR000030 [H]

Pfam domain/function: PF08237 PE-PPE; PF01469 Pentapeptide_2; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 34748; Mature: 34748

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLGNGSRPNGGLMSRFDGAYIPILDVSFIGPTPTTTAGATPGEITTYDIARQYDLFADF
CCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHEECC
PTNPLNILAVANAFAGQLFVHPDYGSVDMSQAVFQGTYGDTAYYLIPTYPLPLLMPLTWI
CCCCEEEEEEHHHHCCEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
PVIGPIAVDMLDPVLRVLVEAGYDRTINPGVPTPANFLYLPDPVTLGSSLLHAIPTGLTY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCC
GTQDILHLREPGTPPPGVAGQDAYGIGGPSVTLPNQTPPPAPPVQTVAAPSTPKVPSATP
CCHHHHEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEECCCCCCCCCCCCC
TTAVPLSDGVNDSVIPSTSPPAPKQHIVDEPIGGSSSNGAVKRSASTADDAPADASTQSR
CEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
PKSSGTTDRPSGAGNSNGKGGSSSSSTGNSNGKGSSSSTGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLGNGSRPNGGLMSRFDGAYIPILDVSFIGPTPTTTAGATPGEITTYDIARQYDLFADF
CCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHEECC
PTNPLNILAVANAFAGQLFVHPDYGSVDMSQAVFQGTYGDTAYYLIPTYPLPLLMPLTWI
CCCCEEEEEEHHHHCCEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHH
PVIGPIAVDMLDPVLRVLVEAGYDRTINPGVPTPANFLYLPDPVTLGSSLLHAIPTGLTY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCC
GTQDILHLREPGTPPPGVAGQDAYGIGGPSVTLPNQTPPPAPPVQTVAAPSTPKVPSATP
CCHHHHEECCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEECCCCCCCCCCCCC
TTAVPLSDGVNDSVIPSTSPPAPKQHIVDEPIGGSSSNGAVKRSASTADDAPADASTQSR
CEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
PKSSGTTDRPSGAGNSNGKGGSSSSSTGNSNGKGSSSSTGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]