Click here to switch to the map view.

The map label for this gene is 108797360

Identifier: 108797360

GI number: 108797360

Start: 425844

End: 427229

Strand: Direct

Name: 108797360

Synonym: Mmcs_0380

Alternate gene names: NA

Gene position: 425844-427229 (Clockwise)

Preceding gene: 108797359

Following gene: 108797361

Centisome position: 7.46

GC content: 73.59

Gene sequence:

>1386_bases
GTGATCCGATCCCTCGCCTTGCTCGCCGTCACCGGTGCGGTCGCGCTGCTCGCCGCACCGTCGGCCGCTGCGGTGACCCC
ACCGCAGGTGGATCCCGCGACACCGCCGCCGTCGGGCACCGCCGGACCGGTGCAGCCGATGGCGCAGCGTGGGGACTGTG
TGGTCGGCGGTGTGCTGGCCGGCAGCGATCCCGGTGCGGTCAGCCCGAACCAGTTGGCGCTCAACCTGTCCGGTGCGTGG
CGGCACAGCCGCGGCGAGGGTCAGACGGTCGCCGTCATCGACACCGGCGTCAAGCCGGGGCCGCGGCTGCCGAACGTCGA
ACCGGGCGGCGACTTCCTGGGCTCGACCGACGGGCTCACCGACTGCGACGGGCACGGCACACTGGTCGCCGGGCTGATCG
CCGGACAACCCGGCGCCGACGGCTTCTCCGGGGTGGCGCCGGGCGCGCGCATCGTCTCCATCCGGCAGAACTCGCCGCGG
TTCTCCCCGGTCAACCCGGGGGAGGACCCCGCGGTGTCGCGCGCCGCCGCCGACGTCGCGAGCCTGGCCCGGGCCGTCGT
ACGGGCCGCCGATCTCGGCGCGCGCGTCATCAACATCTCGGTGGTCAGCTGCCTGCCCGCGGGCCGCAGCGTCGACCAGA
CCGAACTCGGTGCGGCGCTGCGATATGCGGCCCGGGAGAAGGATGCGGTGATCGTGGCCGCGGCGGGTAACGACCGCGCC
GGTATGAACACCGGATCGGCCTGTGAGTCCAATCCGCCCGGCGACGCCGCCCGCCCGGACGACCCGCGCAACTGGGCCGG
CGTCACGTCGGTGTCGATCCCGTCGTGGTGGCAGCCGTACGTGCTGTCCGTGGGGTCGCTGACCAGCACCGGTCAGCCCT
CGGACTTCACCATGTCCGGTCCGTGGGTCGGTATCGCCGCGCCGGGGGAGAACATCACCTCGGTGAGCAACGGACCCGAC
GGCGGGCTCGCCAACGGGCTGCCCAACGACCGCGACGAGCTGTTCCCGGTCAGCGGCACGAGTTATGCGGCCGCGTATGT
GTCCGGGGTTGCGGCGCTGGTGCGCAGCAGATTCCCCGAACTCACCGCAGAACAGGTGGTGGCGCGGCTGACCGCCACGG
CCCACGGTGGCCCACGATCGCCGTCGAACGTGGTGGGCGCCGGCAGCGTCGATCCGGTCGCCGCGCTCACCTGGCGGGTG
CCCTCCGCCACCGCCGCCGCCGCGGTTGCGTCGAAACCGATTGCGGCGCCGCCGAATCCGCCGGTACCCGACCACACTCC
CCGAACGGTCGCGCTGATCGGCACGGCGGCGCTCGCGCTGACGGTGCTCGCCGCGCTGGCCTGGCGCTCGGGGGCGACCC
GACCACGAAAGGACGAGGCCTCATGA

Upstream 100 bases:

>100_bases
CCATGCGCAGGCTCGTGGGGTTCGCCGCGACGGCAGTCGACGCCTCGCTGATCCCCGTGATGGCCCTGCTCGTCGGACTG
TTCAGCTGGGTGCTCAACAG

Downstream 100 bases:

>100_bases
CGGCCAGGATCACGTTGGCGCTTCTGTTCGCCCTACCGGCGGCGCTGGCGTACCCGTGGCAGACCGACACCGACTGGTGG
CTGCTCGGTGTGGCGATTGC

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MIRSLALLAVTGAVALLAAPSAAAVTPPQVDPATPPPSGTAGPVQPMAQRGDCVVGGVLAGSDPGAVSPNQLALNLSGAW
RHSRGEGQTVAVIDTGVKPGPRLPNVEPGGDFLGSTDGLTDCDGHGTLVAGLIAGQPGADGFSGVAPGARIVSIRQNSPR
FSPVNPGEDPAVSRAAADVASLARAVVRAADLGARVINISVVSCLPAGRSVDQTELGAALRYAAREKDAVIVAAAGNDRA
GMNTGSACESNPPGDAARPDDPRNWAGVTSVSIPSWWQPYVLSVGSLTSTGQPSDFTMSGPWVGIAAPGENITSVSNGPD
GGLANGLPNDRDELFPVSGTSYAAAYVSGVAALVRSRFPELTAEQVVARLTATAHGGPRSPSNVVGAGSVDPVAALTWRV
PSATAAAAVASKPIAAPPNPPVPDHTPRTVALIGTAALALTVLAALAWRSGATRPRKDEAS

Sequences:

>Translated_461_residues
MIRSLALLAVTGAVALLAAPSAAAVTPPQVDPATPPPSGTAGPVQPMAQRGDCVVGGVLAGSDPGAVSPNQLALNLSGAW
RHSRGEGQTVAVIDTGVKPGPRLPNVEPGGDFLGSTDGLTDCDGHGTLVAGLIAGQPGADGFSGVAPGARIVSIRQNSPR
FSPVNPGEDPAVSRAAADVASLARAVVRAADLGARVINISVVSCLPAGRSVDQTELGAALRYAAREKDAVIVAAAGNDRA
GMNTGSACESNPPGDAARPDDPRNWAGVTSVSIPSWWQPYVLSVGSLTSTGQPSDFTMSGPWVGIAAPGENITSVSNGPD
GGLANGLPNDRDELFPVSGTSYAAAYVSGVAALVRSRFPELTAEQVVARLTATAHGGPRSPSNVVGAGSVDPVAALTWRV
PSATAAAAVASKPIAAPPNPPVPDHTPRTVALIGTAALALTVLAALAWRSGATRPRKDEAS
>Mature_461_residues
MIRSLALLAVTGAVALLAAPSAAAVTPPQVDPATPPPSGTAGPVQPMAQRGDCVVGGVLAGSDPGAVSPNQLALNLSGAW
RHSRGEGQTVAVIDTGVKPGPRLPNVEPGGDFLGSTDGLTDCDGHGTLVAGLIAGQPGADGFSGVAPGARIVSIRQNSPR
FSPVNPGEDPAVSRAAADVASLARAVVRAADLGARVINISVVSCLPAGRSVDQTELGAALRYAAREKDAVIVAAAGNDRA
GMNTGSACESNPPGDAARPDDPRNWAGVTSVSIPSWWQPYVLSVGSLTSTGQPSDFTMSGPWVGIAAPGENITSVSNGPD
GGLANGLPNDRDELFPVSGTSYAAAYVSGVAALVRSRFPELTAEQVVARLTATAHGGPRSPSNVVGAGSVDPVAALTWRV
PSATAAAAVASKPIAAPPNPPVPDHTPRTVALIGTAALALTVLAALAWRSGATRPRKDEAS

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 45957; Mature: 45957

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00137 SUBTILASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSLALLAVTGAVALLAAPSAAAVTPPQVDPATPPPSGTAGPVQPMAQRGDCVVGGVLA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEEE
GSDPGAVSPNQLALNLSGAWRHSRGEGQTVAVIDTGVKPGPRLPNVEPGGDFLGSTDGLT
CCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
DCDGHGTLVAGLIAGQPGADGFSGVAPGARIVSIRQNSPRFSPVNPGEDPAVSRAAADVA
CCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SLARAVVRAADLGARVINISVVSCLPAGRSVDQTELGAALRYAAREKDAVIVAAAGNDRA
HHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCC
GMNTGSACESNPPGDAARPDDPRNWAGVTSVSIPSWWQPYVLSVGSLTSTGQPSDFTMSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHEECCCCCCCCCCCEEECC
PWVGIAAPGENITSVSNGPDGGLANGLPNDRDELFPVSGTSYAAAYVSGVAALVRSRFPE
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCEEECCCCHHHHHHHHHHHHHHHHHCCC
LTAEQVVARLTATAHGGPRSPSNVVGAGSVDPVAALTWRVPSATAAAAVASKPIAAPPNP
HHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCC
PVPDHTPRTVALIGTAALALTVLAALAWRSGATRPRKDEAS
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIRSLALLAVTGAVALLAAPSAAAVTPPQVDPATPPPSGTAGPVQPMAQRGDCVVGGVLA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEEE
GSDPGAVSPNQLALNLSGAWRHSRGEGQTVAVIDTGVKPGPRLPNVEPGGDFLGSTDGLT
CCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
DCDGHGTLVAGLIAGQPGADGFSGVAPGARIVSIRQNSPRFSPVNPGEDPAVSRAAADVA
CCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH
SLARAVVRAADLGARVINISVVSCLPAGRSVDQTELGAALRYAAREKDAVIVAAAGNDRA
HHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCC
GMNTGSACESNPPGDAARPDDPRNWAGVTSVSIPSWWQPYVLSVGSLTSTGQPSDFTMSG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHEECCCCCCCCCCCEEECC
PWVGIAAPGENITSVSNGPDGGLANGLPNDRDELFPVSGTSYAAAYVSGVAALVRSRFPE
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHCEEECCCCHHHHHHHHHHHHHHHHHCCC
LTAEQVVARLTATAHGGPRSPSNVVGAGSVDPVAALTWRVPSATAAAAVASKPIAAPPNP
HHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCC
PVPDHTPRTVALIGTAALALTVLAALAWRSGATRPRKDEAS
CCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]