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The map label for this gene is hsaC [H]

Identifier: 108797297

GI number: 108797297

Start: 355135

End: 356043

Strand: Reverse

Name: hsaC [H]

Synonym: Mmcs_0317

Alternate gene names: 108797297

Gene position: 356043-355135 (Counterclockwise)

Preceding gene: 108797298

Following gene: 108797296

Centisome position: 6.24

GC content: 68.1

Gene sequence:

>909_bases
ATGACAGTGTTGAAGAGCCTCGGCTACGTCACCGTGCAGACCGCCGACATCGACCGGTGGCGGCACTTCGCCTTCCAGGT
TCTGGGTTTCGCCGAGGGCAGCGGACCCGACGACTCGTGTCTCTATCTGCGGATGGACGAGCGGGCCGCCCGCATCATCG
TGCGCCCCGGTGACACCGACCGGATCGTCACCGTGGGCTGGGAGGTGCGCGACCATGCGGCGCTCGAACAGGTCAAGCGC
GACCTGGATGCGGCAGGGACGCCGTTCAAACAGCTCTCGCTCGAAGAGGCCGACGCCCGCAGGGTCGAGGAGGTCATCGC
GTTCGAGGATCCCGCGGGCACCGCACTGGAGGTGTTCCACGGGGCGGTGCTCGACCACAGCCCCGTCGTGACGCCGTTCG
GAGCCCGATTCGTCACCGGCGCACAGGGTCTCGGCCATGTGGTGCTGCCCGCACTGGACGTGAACGGGGTCTTCGAGTTC
TACACCGGGGTGCTGGGCTTCCGGTCCCGTGGGGCGTTCCGCGTTCCCGTACCGCCCGAGTTCGGCCCGGTTCGGGTGCG
CTTCCTCGGCATCAACGACCGCCACCACAGCCTGGCGATCTGCCCCGCGTCGACCGTGCGTGATCCCGGTCTGGTGCACC
TGATGGTGGAGGTGGACAGCCTCGACGCCGTCGGCCAGGCGCTGGACCGGGTGGCCGCCGACGGATACCAGCTGTCCTCG
ACACTGGGCCGGCACACCAACGACAAGATGGTGTCGTTCTACGTCCGCGCACCCGGCGACTGGGACATCGAATTCGGCAC
CGAGGGGATGCGGGTCGACGAAACCTATTACACCGCTGAGGAGATCACCGCCGACAGCTACTGGGGCCACCAGTGGGTGG
GTGACCTCCCCGCGGCGATGCGCCCGTGA

Upstream 100 bases:

>100_bases
CCACACGCCCGGCACCATCTACCACGCGTCCGCGCTGAGCTCACTGGGCGTCGACCCCCAGGGCGCGTTGCGGGCAATGA
TCTGAGCAGGGAGACGACAG

Downstream 100 bases:

>100_bases
CGGCCGACGACGTCCGGCCCGTCCCCGCCTCGTCGGTCACCTCCTGGGACCACGAGGCCGACGTGGTGATCGCCGGGTAC
GGCGTCGCCGGTGCCGCCGC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTVLKSLGYVTVQTADIDRWRHFAFQVLGFAEGSGPDDSCLYLRMDERAARIIVRPGDTDRIVTVGWEVRDHAALEQVKR
DLDAAGTPFKQLSLEEADARRVEEVIAFEDPAGTALEVFHGAVLDHSPVVTPFGARFVTGAQGLGHVVLPALDVNGVFEF
YTGVLGFRSRGAFRVPVPPEFGPVRVRFLGINDRHHSLAICPASTVRDPGLVHLMVEVDSLDAVGQALDRVAADGYQLSS
TLGRHTNDKMVSFYVRAPGDWDIEFGTEGMRVDETYYTAEEITADSYWGHQWVGDLPAAMRP

Sequences:

>Translated_302_residues
MTVLKSLGYVTVQTADIDRWRHFAFQVLGFAEGSGPDDSCLYLRMDERAARIIVRPGDTDRIVTVGWEVRDHAALEQVKR
DLDAAGTPFKQLSLEEADARRVEEVIAFEDPAGTALEVFHGAVLDHSPVVTPFGARFVTGAQGLGHVVLPALDVNGVFEF
YTGVLGFRSRGAFRVPVPPEFGPVRVRFLGINDRHHSLAICPASTVRDPGLVHLMVEVDSLDAVGQALDRVAADGYQLSS
TLGRHTNDKMVSFYVRAPGDWDIEFGTEGMRVDETYYTAEEITADSYWGHQWVGDLPAAMRP
>Mature_301_residues
TVLKSLGYVTVQTADIDRWRHFAFQVLGFAEGSGPDDSCLYLRMDERAARIIVRPGDTDRIVTVGWEVRDHAALEQVKRD
LDAAGTPFKQLSLEEADARRVEEVIAFEDPAGTALEVFHGAVLDHSPVVTPFGARFVTGAQGLGHVVLPALDVNGVFEFY
TGVLGFRSRGAFRVPVPPEFGPVRVRFLGINDRHHSLAICPASTVRDPGLVHLMVEVDSLDAVGQALDRVAADGYQLSST
LGRHTNDKMVSFYVRAPGDWDIEFGTEGMRVDETYYTAEEITADSYWGHQWVGDLPAAMRP

Specific function: Catalyzes the meta-cleavage of 3,4-dihydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) to produce 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4- oic acid (4,9-DSHA). Also involved in biphenyl and polychlorinated biphenyls

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 33258; Mature: 33127

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLKSLGYVTVQTADIDRWRHFAFQVLGFAEGSGPDDSCLYLRMDERAARIIVRPGDTD
CCCHHHCCEEEEEECCHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCEEEEEECCCCCC
RIVTVGWEVRDHAALEQVKRDLDAAGTPFKQLSLEEADARRVEEVIAFEDPAGTALEVFH
EEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHH
GAVLDHSPVVTPFGARFVTGAQGLGHVVLPALDVNGVFEFYTGVLGFRSRGAFRVPVPPE
HHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEECCCCCC
FGPVRVRFLGINDRHHSLAICPASTVRDPGLVHLMVEVDSLDAVGQALDRVAADGYQLSS
CCCEEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEHHH
TLGRHTNDKMVSFYVRAPGDWDIEFGTEGMRVDETYYTAEEITADSYWGHQWVGDLPAAM
HHCCCCCCCEEEEEEECCCCCEEEECCCCCEECCEEECHHHHCCCCCCCCCHHCCCCCCC
RP
CC
>Mature Secondary Structure 
TVLKSLGYVTVQTADIDRWRHFAFQVLGFAEGSGPDDSCLYLRMDERAARIIVRPGDTD
CCHHHCCEEEEEECCHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCEEEEEECCCCCC
RIVTVGWEVRDHAALEQVKRDLDAAGTPFKQLSLEEADARRVEEVIAFEDPAGTALEVFH
EEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHH
GAVLDHSPVVTPFGARFVTGAQGLGHVVLPALDVNGVFEFYTGVLGFRSRGAFRVPVPPE
HHHCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCEECCCCCC
FGPVRVRFLGINDRHHSLAICPASTVRDPGLVHLMVEVDSLDAVGQALDRVAADGYQLSS
CCCEEEEEEEECCCCCEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCEEHHH
TLGRHTNDKMVSFYVRAPGDWDIEFGTEGMRVDETYYTAEEITADSYWGHQWVGDLPAAM
HHCCCCCCCEEEEEEECCCCCEEEECCCCCEECCEEECHHHHCCCCCCCCCHHCCCCCCC
RP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA