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The map label for this gene is paaF [H]

Identifier: 108797158

GI number: 108797158

Start: 197910

End: 198785

Strand: Direct

Name: paaF [H]

Synonym: Mmcs_0178

Alternate gene names: 108797158

Gene position: 197910-198785 (Clockwise)

Preceding gene: 108797157

Following gene: 108797160

Centisome position: 3.47

GC content: 71.23

Gene sequence:

>876_bases
GTGGAACTGGCAGGCGGCATCCGCGTCGCGGTCGAAACCCCTTGCGACGACGCCTCGTTCACGCTGACCGAGGCGCCGTC
CGACGATCCGCGGCTGGTCACCGTCGCATCGGTGGCCGATACGCTCGCCGAACTCGACGAGCGTTGTCGTCGGTGGCCGC
AGGCCGCGGCGGTATGCGACGACGTGTTGCGCTCATTCGATCCCGCGCGATCCACGTTCGCCGGGGTGATCACCGAATCG
CTGGCCTATTCGACGTTGCAATCGGGCCCGGAGTTCGGCCGCTGGCTCGCCGAACGCGGCTCGGCGCAGGCCCCCGAGAC
CGCGAATCCTGTTGTGGCAGAACGCAACGACGGGCGCCTGACCGTCCGCTTCAACCGGCCCGATCGCCACAACGCATTCT
CCACGGGTGCCCGTGCCGCACTGCTCGAGGCGCTCGAGGTGGCCCGGCTCGATCCCTCGGTCGATGAGGTGGTGCTGTCC
GGGGTCGGTCGATCGTTCTCCAGCGGTGGCGATCTCGCCGAGTTCGGCAGCTTCGACGACCCGGCCTCCGCGCACCTCGC
GCGGACCCGGCACAGCCCGGCCCTGGTGCTCGACGAGGTGACGGCGCGCCTCGGCCGGCGGTGCCGCGCGCAGGTGCACG
GTCAGGTGCTGGGGAGCGGGTTGGAGATGGCGGCCTTCTGCGGATGGGTGGTCAGCAGCCCGGACGCGGTGTTCGGCCTG
CCCGAACTGACCCTCGGGCTGATCCCGGGCGCGGGCGGCACGGTCAGCATCACCCGCCGGATCGGACGGTGGCGAACCGG
CTACCTGGTGCTGTCCGGGCGGACGATCGACCCGTCGACCGCCCTGCGGTGGGGCCTGGTGGACGCCGTCGAATGA

Upstream 100 bases:

>100_bases
AGTGTCCGCGGTCGCTGTCGTTCGAACCTCAGCTGCCCCGCACGGACACCGGCAAGCTCTACAAGCAGGAGTTGATCAAG
AAGTACTCGTGAACGATCCG

Downstream 100 bases:

>100_bases
CCGGAGACCGGGCGAGGAGCGCCCGGGGGGAATGGGCGCTCCTCGCGATCGGGGGCGGTCAGTGATGACCGGTCCGCAGT
GTCAAACGGGACGGATACCG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MELAGGIRVAVETPCDDASFTLTEAPSDDPRLVTVASVADTLAELDERCRRWPQAAAVCDDVLRSFDPARSTFAGVITES
LAYSTLQSGPEFGRWLAERGSAQAPETANPVVAERNDGRLTVRFNRPDRHNAFSTGARAALLEALEVARLDPSVDEVVLS
GVGRSFSSGGDLAEFGSFDDPASAHLARTRHSPALVLDEVTARLGRRCRAQVHGQVLGSGLEMAAFCGWVVSSPDAVFGL
PELTLGLIPGAGGTVSITRRIGRWRTGYLVLSGRTIDPSTALRWGLVDAVE

Sequences:

>Translated_291_residues
MELAGGIRVAVETPCDDASFTLTEAPSDDPRLVTVASVADTLAELDERCRRWPQAAAVCDDVLRSFDPARSTFAGVITES
LAYSTLQSGPEFGRWLAERGSAQAPETANPVVAERNDGRLTVRFNRPDRHNAFSTGARAALLEALEVARLDPSVDEVVLS
GVGRSFSSGGDLAEFGSFDDPASAHLARTRHSPALVLDEVTARLGRRCRAQVHGQVLGSGLEMAAFCGWVVSSPDAVFGL
PELTLGLIPGAGGTVSITRRIGRWRTGYLVLSGRTIDPSTALRWGLVDAVE
>Mature_291_residues
MELAGGIRVAVETPCDDASFTLTEAPSDDPRLVTVASVADTLAELDERCRRWPQAAAVCDDVLRSFDPARSTFAGVITES
LAYSTLQSGPEFGRWLAERGSAQAPETANPVVAERNDGRLTVRFNRPDRHNAFSTGARAALLEALEVARLDPSVDEVVLS
GVGRSFSSGGDLAEFGSFDDPASAHLARTRHSPALVLDEVTARLGRRCRAQVHGQVLGSGLEMAAFCGWVVSSPDAVFGL
PELTLGLIPGAGGTVSITRRIGRWRTGYLVLSGRTIDPSTALRWGLVDAVE

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=185, Percent_Identity=32.972972972973, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI68989263, Length=160, Percent_Identity=34.375, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787659, Length=183, Percent_Identity=35.5191256830601, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788682, Length=137, Percent_Identity=36.4963503649635, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790281, Length=174, Percent_Identity=29.8850574712644, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788597, Length=178, Percent_Identity=26.9662921348315, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI221142681, Length=179, Percent_Identity=28.4916201117318, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=191, Percent_Identity=30.8900523560209, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=169, Percent_Identity=30.1775147928994, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=190, Percent_Identity=31.0526315789474, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=185, Percent_Identity=27.5675675675676, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=165, Percent_Identity=31.5151515151515, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129971, Length=180, Percent_Identity=31.6666666666667, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24653477, Length=180, Percent_Identity=31.6666666666667, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24654903, Length=180, Percent_Identity=25.5555555555556, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653139, Length=219, Percent_Identity=27.8538812785388, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 30959; Mature: 30959

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELAGGIRVAVETPCDDASFTLTEAPSDDPRLVTVASVADTLAELDERCRRWPQAAAVCD
CCCCCCEEEEEECCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHH
DVLRSFDPARSTFAGVITESLAYSTLQSGPEFGRWLAERGSAQAPETANPVVAERNDGRL
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCEE
TVRFNRPDRHNAFSTGARAALLEALEVARLDPSVDEVVLSGVGRSFSSGGDLAEFGSFDD
EEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCC
PASAHLARTRHSPALVLDEVTARLGRRCRAQVHGQVLGSGLEMAAFCGWVVSSPDAVFGL
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCC
PELTLGLIPGAGGTVSITRRIGRWRTGYLVLSGRTIDPSTALRWGLVDAVE
CHHHHEEECCCCCEEHHHHHHCCCEEEEEEEECCEECHHHHHHHCCHHCCC
>Mature Secondary Structure
MELAGGIRVAVETPCDDASFTLTEAPSDDPRLVTVASVADTLAELDERCRRWPQAAAVCD
CCCCCCEEEEEECCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCHHHHHHHH
DVLRSFDPARSTFAGVITESLAYSTLQSGPEFGRWLAERGSAQAPETANPVVAERNDGRL
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCEE
TVRFNRPDRHNAFSTGARAALLEALEVARLDPSVDEVVLSGVGRSFSSGGDLAEFGSFDD
EEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCC
PASAHLARTRHSPALVLDEVTARLGRRCRAQVHGQVLGSGLEMAAFCGWVVSSPDAVFGL
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCC
PELTLGLIPGAGGTVSITRRIGRWRTGYLVLSGRTIDPSTALRWGLVDAVE
CHHHHEEECCCCCEEHHHHHHCCCEEEEEEEECCEECHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]