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The map label for this gene is aidB [H]

Identifier: 108797090

GI number: 108797090

Start: 124241

End: 126007

Strand: Direct

Name: aidB [H]

Synonym: Mmcs_0110

Alternate gene names: 108797090

Gene position: 124241-126007 (Clockwise)

Preceding gene: 108797089

Following gene: 108797092

Centisome position: 2.18

GC content: 67.46

Gene sequence:

>1767_bases
ATGAAATCGACGCTGCTGTCGCGCCGCGACCTGGACTTCCTGCTCTTCGAGTGGCTCCGGGTCGACGAGCTGACACAGCG
GCCACGATTCGCCGACCATTCGCACGACACGTTCACCGGCGTGCTCGACCTGTGTGAACAGCTCGCCGAACGGTACTTCG
CCCCCCACAACAAGAAGAGCGACGCCCACGAACCGACCTTCGACGGCGAGAAGGTGACAGTGATCCCCGAGGTCAAAGAG
GCCTGGGAGGCGTTCGCCGCGGCGGACCTGCTGGCGATGGGGATGGACGCCGAACTCGGCGGCGCGCAGCTGCCCGCGAC
GGTCGCCCAGGCCGCGTTCGCGTGGATCTCGGCGGCGAACCTCGCCACGTCGGGCTACCTGATGCTCACGATCGCGAACG
CGAATCTGCTGGCCGAGTTCGGAACGGCCGAGCAGATCGACAGGTTCGTCAGGCCGATGCTGGCCGGGCGGTTCTCCGGC
ACGATGGCGCTGTCCGAGACGCAGGCCGGATCGTCTCTGGCGGATATCACCACCCGCGCCGAACCGCGGGACGACGGCAC
CTACCGGCTGTTCGGGTCGAAGATGTGGATCTCCGGCGCCGAGCACGAGATCACCGAGAACATCGTCAACCTGGTGCTGG
CGAAGATTCCCGGCGGCCCGCCGGGCACCAAGGGCATCTCGCTGTTCGTCGTGCCGAAATACCTTGTCGCCGAGGATGGT
TCGGTGGGTGAGCGCAACGACGTGGTGCTGGCCGGGCTGAACCACAAGATGGGCCAGCGCGGCATCACCAACACCGTCCT
CAACTTCGGCGAGGGGGTCTTCAACCCGGGCGGCGAGCCCGGCGCGGTCGGCTATCTGGTCGGCGAACCGCACCGCGGCA
TCACCTACATGTTCCGGATGATGAACGAGGCACGCCTGGGTGTCGGCATGGGCGCGGTCGCGCTCGGCTACACCGGCTAC
CTGAAGTCGGTGAAATACGCCCGCGAACGCCCGCAGGGCAGGCCGGTCACCGCCAAGGACCCGGCCACACCGCAGGTGCC
GATCATCGAACACGCCGACGTGAAGCGAATGTTGTTGGCGCAGAAGTCCTATGTCGAGGGCGCGCTGGCACTCGCGCTGT
ACTGTGCGCGGCTGGTCGACCTCGGCGACAACCAGGATCTGCTCGACATCCTCACGCCCGTCGCCAAGAGTTGGCCGTCG
CAGTGGTGTCTGGAGGCCAACAGCCTGGCGATCCAGGTCCACGGCGGCTACGGCTACACCCGCGAATACGACGTCGAACA
GCACTACCGCGACAACCGCCTCAACCCGATCCACGAGGGGACCCACGGCATCCAGAGCCTGGATCTGCTCGGCCGCAAGG
TCACCCAGCGCGGTGGCGCAAGCCTGCGCGCGGTGGGCGGGGCGCTGGCGGCGACGGTGGCCGCCGCGGGTGAATGCGGT
GGTGAGGCAGCGTCATTGGCGGAGGAACTCGACGCGCGGTGGCAGCGGCTGGTCGCCGTCACCACCGCGATGTTCGGCTC
CGGCGACATCGAGGCGGCGATGGCCAACAGCGTCGTCTACCTCGAGGCGTTCGGGCACGTGGTGATCGCCTGGATGTGGC
TCGAGCAGTTCCTCGCCGCCGAGGGCCGGACCGGTGACTTCTACGACGGCAAACGGCAGGCGGCGCGGTTCTTCTACCGG
TACGAGCTGCCGAAGGTCGGACCCCAGCTCGACCTGCTCGACAGCCTGGACCGGACCACGCTGGAGATGCGCGACTCCTG
GTTCTAG

Upstream 100 bases:

>100_bases
CCGACGACATGGCCGGGATCGCGGTGTTCCTGGCCAGCCGGGCCAGCGCCTACATCACCGGCGCGATCATCCCCGTCGAC
GGCGGCGTCAGCACGATCCG

Downstream 100 bases:

>100_bases
TCGAACTCGATGACCTGGCGGACGGCCTTGCCCTCGGCCAGGCGGTCCATACCGGCATTGATCTCGTCGAGTGAGATCGT
CGAGGACACCAGGGTTTCCA

Product: acyl-CoA dehydrogenase-like protein

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MKSTLLSRRDLDFLLFEWLRVDELTQRPRFADHSHDTFTGVLDLCEQLAERYFAPHNKKSDAHEPTFDGEKVTVIPEVKE
AWEAFAAADLLAMGMDAELGGAQLPATVAQAAFAWISAANLATSGYLMLTIANANLLAEFGTAEQIDRFVRPMLAGRFSG
TMALSETQAGSSLADITTRAEPRDDGTYRLFGSKMWISGAEHEITENIVNLVLAKIPGGPPGTKGISLFVVPKYLVAEDG
SVGERNDVVLAGLNHKMGQRGITNTVLNFGEGVFNPGGEPGAVGYLVGEPHRGITYMFRMMNEARLGVGMGAVALGYTGY
LKSVKYARERPQGRPVTAKDPATPQVPIIEHADVKRMLLAQKSYVEGALALALYCARLVDLGDNQDLLDILTPVAKSWPS
QWCLEANSLAIQVHGGYGYTREYDVEQHYRDNRLNPIHEGTHGIQSLDLLGRKVTQRGGASLRAVGGALAATVAAAGECG
GEAASLAEELDARWQRLVAVTTAMFGSGDIEAAMANSVVYLEAFGHVVIAWMWLEQFLAAEGRTGDFYDGKRQAARFFYR
YELPKVGPQLDLLDSLDRTTLEMRDSWF

Sequences:

>Translated_588_residues
MKSTLLSRRDLDFLLFEWLRVDELTQRPRFADHSHDTFTGVLDLCEQLAERYFAPHNKKSDAHEPTFDGEKVTVIPEVKE
AWEAFAAADLLAMGMDAELGGAQLPATVAQAAFAWISAANLATSGYLMLTIANANLLAEFGTAEQIDRFVRPMLAGRFSG
TMALSETQAGSSLADITTRAEPRDDGTYRLFGSKMWISGAEHEITENIVNLVLAKIPGGPPGTKGISLFVVPKYLVAEDG
SVGERNDVVLAGLNHKMGQRGITNTVLNFGEGVFNPGGEPGAVGYLVGEPHRGITYMFRMMNEARLGVGMGAVALGYTGY
LKSVKYARERPQGRPVTAKDPATPQVPIIEHADVKRMLLAQKSYVEGALALALYCARLVDLGDNQDLLDILTPVAKSWPS
QWCLEANSLAIQVHGGYGYTREYDVEQHYRDNRLNPIHEGTHGIQSLDLLGRKVTQRGGASLRAVGGALAATVAAAGECG
GEAASLAEELDARWQRLVAVTTAMFGSGDIEAAMANSVVYLEAFGHVVIAWMWLEQFLAAEGRTGDFYDGKRQAARFFYR
YELPKVGPQLDLLDSLDRTTLEMRDSWF
>Mature_588_residues
MKSTLLSRRDLDFLLFEWLRVDELTQRPRFADHSHDTFTGVLDLCEQLAERYFAPHNKKSDAHEPTFDGEKVTVIPEVKE
AWEAFAAADLLAMGMDAELGGAQLPATVAQAAFAWISAANLATSGYLMLTIANANLLAEFGTAEQIDRFVRPMLAGRFSG
TMALSETQAGSSLADITTRAEPRDDGTYRLFGSKMWISGAEHEITENIVNLVLAKIPGGPPGTKGISLFVVPKYLVAEDG
SVGERNDVVLAGLNHKMGQRGITNTVLNFGEGVFNPGGEPGAVGYLVGEPHRGITYMFRMMNEARLGVGMGAVALGYTGY
LKSVKYARERPQGRPVTAKDPATPQVPIIEHADVKRMLLAQKSYVEGALALALYCARLVDLGDNQDLLDILTPVAKSWPS
QWCLEANSLAIQVHGGYGYTREYDVEQHYRDNRLNPIHEGTHGIQSLDLLGRKVTQRGGASLRAVGGALAATVAAAGECG
GEAASLAEELDARWQRLVAVTTAMFGSGDIEAAMANSVVYLEAFGHVVIAWMWLEQFLAAEGRTGDFYDGKRQAARFFYR
YELPKVGPQLDLLDSLDRTTLEMRDSWF

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=384, Percent_Identity=26.8229166666667, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI4557233, Length=425, Percent_Identity=29.4117647058824, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI7656849, Length=364, Percent_Identity=26.3736263736264, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=27.1739130434783, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4557235, Length=355, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI76496475, Length=355, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082384, Length=302, Percent_Identity=29.8013245033113, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=315, Percent_Identity=27.6190476190476, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=314, Percent_Identity=26.7515923566879, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=369, Percent_Identity=26.8292682926829, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=319, Percent_Identity=23.5109717868339, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=417, Percent_Identity=24.4604316546763, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=319, Percent_Identity=26.0188087774295, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=335, Percent_Identity=26.5671641791045, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=335, Percent_Identity=26.5671641791045, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=417, Percent_Identity=26.8585131894484, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24666513, Length=402, Percent_Identity=25.1243781094527, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355753, Length=393, Percent_Identity=26.4631043256997, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=27.2965879265092, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: 1.3.99.2

Molecular weight: Translated: 64144; Mature: 64144

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTLLSRRDLDFLLFEWLRVDELTQRPRFADHSHDTFTGVLDLCEQLAERYFAPHNKKS
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
DAHEPTFDGEKVTVIPEVKEAWEAFAAADLLAMGMDAELGGAQLPATVAQAAFAWISAAN
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
LATSGYLMLTIANANLLAEFGTAEQIDRFVRPMLAGRFSGTMALSETQAGSSLADITTRA
HCCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCC
EPRDDGTYRLFGSKMWISGAEHEITENIVNLVLAKIPGGPPGTKGISLFVVPKYLVAEDG
CCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEECCC
SVGERNDVVLAGLNHKMGQRGITNTVLNFGEGVFNPGGEPGAVGYLVGEPHRGITYMFRM
CCCCCCCEEEEECCHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
MNEARLGVGMGAVALGYTGYLKSVKYARERPQGRPVTAKDPATPQVPIIEHADVKRMLLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
QKSYVEGALALALYCARLVDLGDNQDLLDILTPVAKSWPSQWCLEANSLAIQVHGGYGYT
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCCC
REYDVEQHYRDNRLNPIHEGTHGIQSLDLLGRKVTQRGGASLRAVGGALAATVAAAGECG
CCCCHHHHHCCCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GEAASLAEELDARWQRLVAVTTAMFGSGDIEAAMANSVVYLEAFGHVVIAWMWLEQFLAA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEEHHHHHHHHHHHHHHHHHC
EGRTGDFYDGKRQAARFFYRYELPKVGPQLDLLDSLDRTTLEMRDSWF
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHCCCC
>Mature Secondary Structure
MKSTLLSRRDLDFLLFEWLRVDELTQRPRFADHSHDTFTGVLDLCEQLAERYFAPHNKKS
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
DAHEPTFDGEKVTVIPEVKEAWEAFAAADLLAMGMDAELGGAQLPATVAQAAFAWISAAN
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
LATSGYLMLTIANANLLAEFGTAEQIDRFVRPMLAGRFSGTMALSETQAGSSLADITTRA
HCCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHCCC
EPRDDGTYRLFGSKMWISGAEHEITENIVNLVLAKIPGGPPGTKGISLFVVPKYLVAEDG
CCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEECCC
SVGERNDVVLAGLNHKMGQRGITNTVLNFGEGVFNPGGEPGAVGYLVGEPHRGITYMFRM
CCCCCCCEEEEECCHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
MNEARLGVGMGAVALGYTGYLKSVKYARERPQGRPVTAKDPATPQVPIIEHADVKRMLLA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
QKSYVEGALALALYCARLVDLGDNQDLLDILTPVAKSWPSQWCLEANSLAIQVHGGYGYT
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCCC
REYDVEQHYRDNRLNPIHEGTHGIQSLDLLGRKVTQRGGASLRAVGGALAATVAAAGECG
CCCCHHHHHCCCCCCCHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GEAASLAEELDARWQRLVAVTTAMFGSGDIEAAMANSVVYLEAFGHVVIAWMWLEQFLAA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEEEHHHHHHHHHHHHHHHHHC
EGRTGDFYDGKRQAARFFYRYELPKVGPQLDLLDSLDRTTLEMRDSWF
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]