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The map label for this gene is kstR2 [H]

Identifier: 108797089

GI number: 108797089

Start: 122821

End: 123480

Strand: Direct

Name: kstR2 [H]

Synonym: Mmcs_0108

Alternate gene names: 108797089

Gene position: 122821-123480 (Clockwise)

Preceding gene: 108797087

Following gene: 108797090

Centisome position: 2.15

GC content: 67.42

Gene sequence:

>660_bases
ATGTCTGCCGAAGCCTCGCCGAACGGCTCGACGCGGCGCGATGAGCTGCTGAGGGTCGCCACCAAGCTGTTCGCCGCCCG
CGGCTACCACGGCACCCGGATGGATGACGTCGCCGACGCCGTCGGCCTGAACAAGGCCACGGTGTACCACTACTACGCGA
GCAAGTCGCTCATCCTCTACGACATCTACAAAGGCGCCGCCGACTTCACCGTCGACGCACTGCACGACGATCCGACGGCG
TCGGCCCGCGAGACGATCTACCACTTCACCCGCCGGTTGCTCGTCGGCATCGCCAACGACATCGAGCGCGCCGCCGTGTA
CTTCCAGGAGGGCCCCTACATCGGCGAGTGGTTCACCGAGGAGCAGGTCGAGTACATCCGCGAGAAGGAGACCCAGGTCT
ACGAGCACGTGCGTGACGTGATCGACCGGGGCATCGCCAGCGGCGAGTTCTACGACTGCGATTCGCACGTGCTGGCGCTC
GGCTACATCGGGATGACGCTGGGCGCCTACCGCTGGCTGCGGCCCCAGGGCCGGCGCACCGCACAGGAGATCGCCGAGGA
GTTCAGCACCGCACTGCTGCGCGGGCTGATCCGCGACGAGGCGGTGCGCACCGAGTCACCGCTGGGCGTGGACGTCCGGA
CGGGAGTAGGCAGTGACTGA

Upstream 100 bases:

>100_bases
GGGTGGCGGACGTGGACAGGGGTCGGTGGCATTGCCATAGACTGACCGACCAGCCAGTTGATAGACGCCCGTACCGCGGG
CCCGTCGATAGTGAGTCGCC

Downstream 100 bases:

>100_bases
CCTGTTCTCACTCGACGGCAAGGTCGCCGTGGTCACCGGGGGCGGCCGCGGGATCGGCGTGATGATCGCCCGCGGGCTGT
TGCAGGCGGGGGCGTCGGTC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSAEASPNGSTRRDELLRVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVDALHDDPTA
SARETIYHFTRRLLVGIANDIERAAVYFQEGPYIGEWFTEEQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLAL
GYIGMTLGAYRWLRPQGRRTAQEIAEEFSTALLRGLIRDEAVRTESPLGVDVRTGVGSD

Sequences:

>Translated_219_residues
MSAEASPNGSTRRDELLRVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVDALHDDPTA
SARETIYHFTRRLLVGIANDIERAAVYFQEGPYIGEWFTEEQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLAL
GYIGMTLGAYRWLRPQGRRTAQEIAEEFSTALLRGLIRDEAVRTESPLGVDVRTGVGSD
>Mature_218_residues
SAEASPNGSTRRDELLRVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVDALHDDPTAS
ARETIYHFTRRLLVGIANDIERAAVYFQEGPYIGEWFTEEQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALG
YIGMTLGAYRWLRPQGRRTAQEIAEEFSTALLRGLIRDEAVRTESPLGVDVRTGVGSD

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24614; Mature: 24483

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEASPNGSTRRDELLRVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEE
DIYKGAADFTVDALHDDPTASARETIYHFTRRLLVGIANDIERAAVYFQEGPYIGEWFTE
EECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
EQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMTLGAYRWLRPQGRRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
AQEIAEEFSTALLRGLIRDEAVRTESPLGVDVRTGVGSD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
SAEASPNGSTRRDELLRVATKLFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEE
DIYKGAADFTVDALHDDPTASARETIYHFTRRLLVGIANDIERAAVYFQEGPYIGEWFTE
EECCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
EQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMTLGAYRWLRPQGRRT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHH
AQEIAEEFSTALLRGLIRDEAVRTESPLGVDVRTGVGSD
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]