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The map label for this gene is htpG [H]

Identifier: 108763940

GI number: 108763940

Start: 1638227

End: 1640083

Strand: Reverse

Name: htpG [H]

Synonym: MXAN_1393

Alternate gene names: 108763940

Gene position: 1640083-1638227 (Counterclockwise)

Preceding gene: 108763582

Following gene: 108758995

Centisome position: 17.94

GC content: 69.52

Gene sequence:

>1857_bases
GTGGACCACCGATTTCAAGTCAGCCTCCGCGGGGTCATCGACCTCCTGTCACATCACCTGTACAGCTCCCCGGGCGTCTA
CGTACGCGAGCTGCTCCAGAACGCGACCGATGCCATCCGCGCCCGCCAGCTCCTGGAGCCCGGCCACGCGGGCACCGTCC
GGCTGGAGCTGATGGAGAAGCAGGACGGCAGCCCGCCCACCCTGCTCTTCACCGACGACGGCGTGGGGCTGACCGAGGAC
GAAATCCACCGCTTCCTGGCCACCATCGGTGAGTCCTCCAAGCGCGAGGCCCTGGAGGCCCGCCGCAACGACTTCATCGG
CCAGTTCGGTATCGGCCTGCTGTCCTGCTTCATGGTGTGCGACGAGCTGCTGGTGGTGACGCGCTCGGCACGCGGCGACG
GGCGCACGTTGGAGTGGCGGGGCCGGCATGACGGCACGTACGCCGTGCGGCCCTCCGAGCACCCGCTCGCCCAGCCCGGC
ACCCAGGTGTTCCTGGTGGCCCGCCCGGACATGGCGCATTGGTTCACCGCCACGCGGCTGCGAAACCTCGCCAGCCACTA
CGGCGGCCTGCTGCCCTTTCCCATCCACCTCACCACGGACCAGGGCACCGAGCGGCTGGACACCTCCGGCGCCCCCTGGC
GCCGCGAGTACGACAGCGCCTCGGAGCGGCGCAAGGCGCTGCTCGCCTACGGGCGCGAGCTGTTCGACACGGACTTCGTC
GACTGCATCCCCCTGCGCTCCACCGCGGGAGACGTGGACGGGGTGGCCTACGTGCTGCCCGCGTCGCCGCACTTCAACTC
ACGCCAGAAGCACCGCGTGTACCTCAAGCACATGCTGCTGTCGGAGAGCGCGGAGAACCTGCTGCCGGAGTGGGCCTTCT
TCGTGAAGTGCGTGGTGAACGCCAACGCGCTGCGGCCCACCGCCAGCCGGGAGTCCTTCTACGAGGACGACGCGCTCGCC
GCGGCGCGCGAGTCCCTGGGGCAGTCCCTGCGCGGCTACCTGATGGAGCTGGCGCGTGAGGACCCACGCGCGCTCCAGCG
GCTGATTGCCCTGCACGGGCTGAGCGTGAAGGCGCTGGCGCTGGATGACGATGACTTCTACCGCCTCATCATCCACTGGC
TGCCCTTCGAGACGTCGATGGGGATGATGACGCTGGCGGACTACCGGCGCGCGCACCCCGTGGTGCGCTACACGTCCACG
TTGGACGGCTTCCGGCAGATTGCCCAGGTGGCCGGTGCCCAAGGCCTGTGCATCATCAACGCGGCGTACACGCACGACAC
GTCGCTGCTGGAGAAGCTGCCGCACGCGGTGCCGGACGTGCAGGTGGAGCCCTTCTCCTCCGCGGACCTGCCGCAGAGCT
TCGATGAGCTCACCCTGGACGAGCGCGAGGCCACCTTCCCGCTGCTGCGCATGGCGGAGAACGTGCTGGCGCCGTTCCGC
TGCGGCGCGGTGGTGAAGAAGTTCTACCCGGCGGAAGTGCCCACGCTCTACAGCTCGGACGCGGAGGGCGCGTTCCGGCG
CGACGCCGAGCGGGCTCGCGAGGAGTCGGATGACCTATACGCCGGCGTGCTGGACAGCGTCATGGCGGCCTCGGGCAGCG
AGCCGGCGCAGTTGTGCTTCAACCTCCACAACCCGGTGGTGCGGCGGCTGGCCGCCGTGGCGGACCGGGACATGCTGAAG
CTGTCGGTGGAGATGCTCTACGTGCAAGCACTGCTCTTGGGACACCATCCGTTGAACGCACAGGAGATGGTCCTGCTGAA
CCAGGGCCTGTTGGGCCTCATCTCCGCACAACTGGGCGGGGATGGCGGGCGCGGCGGCGAAGGCAGCGGCGGCGCGGGTC
CCCGGGGGCTGCACTGA

Upstream 100 bases:

>100_bases
GCCATTCAAGGGCCCGCCATGGATGCCCAAGTGCACGCCGCGTCTCAAGCTCGATTCGGCTGTCGATACGACGGGGGGCG
TGCGCTAACGTCGGCGGTAC

Downstream 100 bases:

>100_bases
TGAGTGGTGACTGGCGCGAGCAGGTGGAGTCGCTCTTCGCTCAGGCGGACGGCCTGGCTGAAGGCGAGAGCAAGGTGCGG
CTCCTGGAAGAGGCGGTGCG

Product: HSP90 family protein

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MDHRFQVSLRGVIDLLSHHLYSSPGVYVRELLQNATDAIRARQLLEPGHAGTVRLELMEKQDGSPPTLLFTDDGVGLTED
EIHRFLATIGESSKREALEARRNDFIGQFGIGLLSCFMVCDELLVVTRSARGDGRTLEWRGRHDGTYAVRPSEHPLAQPG
TQVFLVARPDMAHWFTATRLRNLASHYGGLLPFPIHLTTDQGTERLDTSGAPWRREYDSASERRKALLAYGRELFDTDFV
DCIPLRSTAGDVDGVAYVLPASPHFNSRQKHRVYLKHMLLSESAENLLPEWAFFVKCVVNANALRPTASRESFYEDDALA
AARESLGQSLRGYLMELAREDPRALQRLIALHGLSVKALALDDDDFYRLIIHWLPFETSMGMMTLADYRRAHPVVRYTST
LDGFRQIAQVAGAQGLCIINAAYTHDTSLLEKLPHAVPDVQVEPFSSADLPQSFDELTLDEREATFPLLRMAENVLAPFR
CGAVVKKFYPAEVPTLYSSDAEGAFRRDAERAREESDDLYAGVLDSVMAASGSEPAQLCFNLHNPVVRRLAAVADRDMLK
LSVEMLYVQALLLGHHPLNAQEMVLLNQGLLGLISAQLGGDGGRGGEGSGGAGPRGLH

Sequences:

>Translated_618_residues
MDHRFQVSLRGVIDLLSHHLYSSPGVYVRELLQNATDAIRARQLLEPGHAGTVRLELMEKQDGSPPTLLFTDDGVGLTED
EIHRFLATIGESSKREALEARRNDFIGQFGIGLLSCFMVCDELLVVTRSARGDGRTLEWRGRHDGTYAVRPSEHPLAQPG
TQVFLVARPDMAHWFTATRLRNLASHYGGLLPFPIHLTTDQGTERLDTSGAPWRREYDSASERRKALLAYGRELFDTDFV
DCIPLRSTAGDVDGVAYVLPASPHFNSRQKHRVYLKHMLLSESAENLLPEWAFFVKCVVNANALRPTASRESFYEDDALA
AARESLGQSLRGYLMELAREDPRALQRLIALHGLSVKALALDDDDFYRLIIHWLPFETSMGMMTLADYRRAHPVVRYTST
LDGFRQIAQVAGAQGLCIINAAYTHDTSLLEKLPHAVPDVQVEPFSSADLPQSFDELTLDEREATFPLLRMAENVLAPFR
CGAVVKKFYPAEVPTLYSSDAEGAFRRDAERAREESDDLYAGVLDSVMAASGSEPAQLCFNLHNPVVRRLAAVADRDMLK
LSVEMLYVQALLLGHHPLNAQEMVLLNQGLLGLISAQLGGDGGRGGEGSGGAGPRGLH
>Mature_618_residues
MDHRFQVSLRGVIDLLSHHLYSSPGVYVRELLQNATDAIRARQLLEPGHAGTVRLELMEKQDGSPPTLLFTDDGVGLTED
EIHRFLATIGESSKREALEARRNDFIGQFGIGLLSCFMVCDELLVVTRSARGDGRTLEWRGRHDGTYAVRPSEHPLAQPG
TQVFLVARPDMAHWFTATRLRNLASHYGGLLPFPIHLTTDQGTERLDTSGAPWRREYDSASERRKALLAYGRELFDTDFV
DCIPLRSTAGDVDGVAYVLPASPHFNSRQKHRVYLKHMLLSESAENLLPEWAFFVKCVVNANALRPTASRESFYEDDALA
AARESLGQSLRGYLMELAREDPRALQRLIALHGLSVKALALDDDDFYRLIIHWLPFETSMGMMTLADYRRAHPVVRYTST
LDGFRQIAQVAGAQGLCIINAAYTHDTSLLEKLPHAVPDVQVEPFSSADLPQSFDELTLDEREATFPLLRMAENVLAPFR
CGAVVKKFYPAEVPTLYSSDAEGAFRRDAERAREESDDLYAGVLDSVMAASGSEPAQLCFNLHNPVVRRLAAVADRDMLK
LSVEMLYVQALLLGHHPLNAQEMVLLNQGLLGLISAQLGGDGGRGGEGSGGAGPRGLH

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=374, Percent_Identity=24.5989304812834, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI4507677, Length=206, Percent_Identity=28.6407766990291, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI20149594, Length=211, Percent_Identity=26.0663507109005, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI154146191, Length=212, Percent_Identity=26.8867924528302, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI153792590, Length=212, Percent_Identity=26.8867924528302, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=24.1269841269841, Blast_Score=125, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI115535167, Length=452, Percent_Identity=25.2212389380531, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI115535205, Length=383, Percent_Identity=24.8041775456919, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17559162, Length=439, Percent_Identity=23.4624145785877, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17542208, Length=378, Percent_Identity=24.3386243386243, Blast_Score=92, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325016, Length=214, Percent_Identity=27.5700934579439, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323840, Length=211, Percent_Identity=27.0142180094787, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586016, Length=426, Percent_Identity=26.9953051643192, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17647529, Length=211, Percent_Identity=27.4881516587678, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21357739, Length=209, Percent_Identity=26.3157894736842, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 68440; Mature: 68440

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHRFQVSLRGVIDLLSHHLYSSPGVYVRELLQNATDAIRARQLLEPGHAGTVRLELMEK
CCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
QDGSPPTLLFTDDGVGLTEDEIHRFLATIGESSKREALEARRNDFIGQFGIGLLSCFMVC
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELLVVTRSARGDGRTLEWRGRHDGTYAVRPSEHPLAQPGTQVFLVARPDMAHWFTATRL
HHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
RNLASHYGGLLPFPIHLTTDQGTERLDTSGAPWRREYDSASERRKALLAYGRELFDTDFV
HHHHHHHCCCCCEEEEEECCCCCHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCH
DCIPLRSTAGDVDGVAYVLPASPHFNSRQKHRVYLKHMLLSESAENLLPEWAFFVKCVVN
HCEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANALRPTASRESFYEDDALAAARESLGQSLRGYLMELAREDPRALQRLIALHGLSVKALA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEE
LDDDDFYRLIIHWLPFETSMGMMTLADYRRAHPVVRYTSTLDGFRQIAQVAGAQGLCIIN
ECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
AAYTHDTSLLEKLPHAVPDVQVEPFSSADLPQSFDELTLDEREATFPLLRMAENVLAPFR
ECHHCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCHHH
CGAVVKKFYPAEVPTLYSSDAEGAFRRDAERAREESDDLYAGVLDSVMAASGSEPAQLCF
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
NLHNPVVRRLAAVADRDMLKLSVEMLYVQALLLGHHPLNAQEMVLLNQGLLGLISAQLGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCC
DGGRGGEGSGGAGPRGLH
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDHRFQVSLRGVIDLLSHHLYSSPGVYVRELLQNATDAIRARQLLEPGHAGTVRLELMEK
CCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
QDGSPPTLLFTDDGVGLTEDEIHRFLATIGESSKREALEARRNDFIGQFGIGLLSCFMVC
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DELLVVTRSARGDGRTLEWRGRHDGTYAVRPSEHPLAQPGTQVFLVARPDMAHWFTATRL
HHHHHHHHCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
RNLASHYGGLLPFPIHLTTDQGTERLDTSGAPWRREYDSASERRKALLAYGRELFDTDFV
HHHHHHHCCCCCEEEEEECCCCCHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCH
DCIPLRSTAGDVDGVAYVLPASPHFNSRQKHRVYLKHMLLSESAENLLPEWAFFVKCVVN
HCEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ANALRPTASRESFYEDDALAAARESLGQSLRGYLMELAREDPRALQRLIALHGLSVKALA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEE
LDDDDFYRLIIHWLPFETSMGMMTLADYRRAHPVVRYTSTLDGFRQIAQVAGAQGLCIIN
ECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
AAYTHDTSLLEKLPHAVPDVQVEPFSSADLPQSFDELTLDEREATFPLLRMAENVLAPFR
ECHHCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCHHH
CGAVVKKFYPAEVPTLYSSDAEGAFRRDAERAREESDDLYAGVLDSVMAASGSEPAQLCF
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
NLHNPVVRRLAAVADRDMLKLSVEMLYVQALLLGHHPLNAQEMVLLNQGLLGLISAQLGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCC
DGGRGGEGSGGAGPRGLH
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA