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The map label for this gene is gatA [H]

Identifier: 108763549

GI number: 108763549

Start: 4154650

End: 4156296

Strand: Direct

Name: gatA [H]

Synonym: MXAN_3566

Alternate gene names: 108763549

Gene position: 4154650-4156296 (Clockwise)

Preceding gene: 108759376

Following gene: 108761412

Centisome position: 45.46

GC content: 72.19

Gene sequence:

>1647_bases
GTGGGCCTCAGCCGCCGCACCGTCCTGCGCGGAACGGCCGCTGCCACGGCGCTCGCCTCACTGGATGTCCCCGCCCATGC
GGCCCCGACGCCGGCGCGGCCCTTCGAGCTGGCCGAGGCCACCGTGGTGGACCTCCAGGCCGCGATGAAGGCAGGCGAGC
TCACCGCGCAAGGCCTCGCGGAGCGCTACCTCGCGCGCATCGCCGACTGGGACTCGCGCGGGCGCCTGCCGCTGCGCTCC
GTCATCGAGCTGAACCCGGACGCGCTCGCCACGGCCGCCGCGCTCGACCAGGAGCGCCGCGAGAAGGGACCCCGGGGCCC
GCTGCACGGCATCCCGGTGCTCCTCAAGGACAACATCGCCACCGCGGACCAGATGCAGACGACGGCGGGTTCCCTGGCGT
TGGTGGGCGCGCGGCCGTCTCGGGACGCGTTCATCGTGGAGCGCCTGCGAGCCGCGGGCGCGGTCATCCTGGGCAAGACG
AACCTGAGCGAGTGGGCCAACTTCCGCTCCACGCGCTCGGCCAGTGGCTGGAGCGCGCGGGGTGGCCAGACGCGCAACCC
GTATGCGCTCGACAGGACGCCTTCGGGCTCCAGTTCGGGGGCGGGTGCGGCCACGGCGGCCAACTTCTGCGCCGTGTCCG
TGGGCACGGAGACGGATGGCTCCATCGTGTCGCCCGCGGCGGCCAGCGCGTTGGTGGGGCTCAAGCCGACGGTGGGACTG
GTGAGCCGCTCCGGCATCATTCCCATCTCCCACAGCCAGGACACGGCCGGCCCCATGACGCGCACCGTGGCGGATGCCGC
GGCGCTGTTGAGCGTGCTCGCGGGCGTGGACCCTTCGGACGGGGCGACGGGGGCGAGCCGGGGCAAGGCCCATGCGGACT
ACACCCGGTTCCTCGATGTGGACGGGCTGAAGGGCGCTCGCATCGGCGTGCCCCGGGAGCGCTTCTTCGGCTACCACCCG
GCCACCGACGCGCTCGTGGAGGAGGCCTTGGCCTTGATGAAGTCCCGCGGCGCCATCCTCGTGGACCCGGCGCCGATTCC
CGCGGTGGCGCAGGTGGACGCCCCCGAACTGGAGGTCCTCCTCTACGAGTTCAAGGCGGGGCTGGAGGCCTACCTTGCGA
CGTTGGAGGAGGGGACGGCCCCGCGCACGCTCGCGGAGCTCATCCGCTACAACGAAGCGCACGCGCCGTCGGAGCTGCCG
TACTTCGGCCAGGAGCTCTTCCACATGGCTCAGGCCAAGGGGCCCCTGACGGACAAGGCCTATCTCAAGGCCCTCCAGGC
TTGCCGCCGCCTGTCGCGCGCGCAGGGGCTGGACGCGGTGATGAAGAAGCACCAGCTGGATGCGCTGGTCGCGCCGACGC
AGGCACCCGTGGGGCTCATCGACCCCATCAACGGTGACCACTGGCTGGGCAGCAGCTCCACGCCCGCGGCCGTATCAGGC
TATGCCTCCATCACCGTGCCCGCGGGGTTCGTGTACGGCTTGCCCGTGGGGCTGTCCTTCATCGGCGGGGCCTGGAGCGA
GCCCGTCCTCTTGAAGCTGGCTCATGCCTATGAACATGCGTCGAAGCACCGCCGCCCGCCCACCTTCGCGGAGACGGCGG
ACCTGCGGGTGCACGCTGGCGCGGGAAGCCCACCCGCGAAGCCCTGA

Upstream 100 bases:

>100_bases
AACCTAACGAAGCCCCACCGGGGTTGCGACTCTTCGCGTGCCGCCGGGGTGCTGTAGCCTCCCCACCATGAAGAAAACCG
CAGCCTCTCCCGGCTCCCCG

Downstream 100 bases:

>100_bases
CTCAGGGCTCCGGCGACGTGGCCCAGGGCGTGGTGGCCTGGAGCACGGCTTCTTGGAGCGCCTCCGTGCGCAGGTGCGCG
ATGTGCTGGTACTCCGGGTC

Product: amidase

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MGLSRRTVLRGTAAATALASLDVPAHAAPTPARPFELAEATVVDLQAAMKAGELTAQGLAERYLARIADWDSRGRLPLRS
VIELNPDALATAAALDQERREKGPRGPLHGIPVLLKDNIATADQMQTTAGSLALVGARPSRDAFIVERLRAAGAVILGKT
NLSEWANFRSTRSASGWSARGGQTRNPYALDRTPSGSSSGAGAATAANFCAVSVGTETDGSIVSPAAASALVGLKPTVGL
VSRSGIIPISHSQDTAGPMTRTVADAAALLSVLAGVDPSDGATGASRGKAHADYTRFLDVDGLKGARIGVPRERFFGYHP
ATDALVEEALALMKSRGAILVDPAPIPAVAQVDAPELEVLLYEFKAGLEAYLATLEEGTAPRTLAELIRYNEAHAPSELP
YFGQELFHMAQAKGPLTDKAYLKALQACRRLSRAQGLDAVMKKHQLDALVAPTQAPVGLIDPINGDHWLGSSSTPAAVSG
YASITVPAGFVYGLPVGLSFIGGAWSEPVLLKLAHAYEHASKHRRPPTFAETADLRVHAGAGSPPAKP

Sequences:

>Translated_548_residues
MGLSRRTVLRGTAAATALASLDVPAHAAPTPARPFELAEATVVDLQAAMKAGELTAQGLAERYLARIADWDSRGRLPLRS
VIELNPDALATAAALDQERREKGPRGPLHGIPVLLKDNIATADQMQTTAGSLALVGARPSRDAFIVERLRAAGAVILGKT
NLSEWANFRSTRSASGWSARGGQTRNPYALDRTPSGSSSGAGAATAANFCAVSVGTETDGSIVSPAAASALVGLKPTVGL
VSRSGIIPISHSQDTAGPMTRTVADAAALLSVLAGVDPSDGATGASRGKAHADYTRFLDVDGLKGARIGVPRERFFGYHP
ATDALVEEALALMKSRGAILVDPAPIPAVAQVDAPELEVLLYEFKAGLEAYLATLEEGTAPRTLAELIRYNEAHAPSELP
YFGQELFHMAQAKGPLTDKAYLKALQACRRLSRAQGLDAVMKKHQLDALVAPTQAPVGLIDPINGDHWLGSSSTPAAVSG
YASITVPAGFVYGLPVGLSFIGGAWSEPVLLKLAHAYEHASKHRRPPTFAETADLRVHAGAGSPPAKP
>Mature_547_residues
GLSRRTVLRGTAAATALASLDVPAHAAPTPARPFELAEATVVDLQAAMKAGELTAQGLAERYLARIADWDSRGRLPLRSV
IELNPDALATAAALDQERREKGPRGPLHGIPVLLKDNIATADQMQTTAGSLALVGARPSRDAFIVERLRAAGAVILGKTN
LSEWANFRSTRSASGWSARGGQTRNPYALDRTPSGSSSGAGAATAANFCAVSVGTETDGSIVSPAAASALVGLKPTVGLV
SRSGIIPISHSQDTAGPMTRTVADAAALLSVLAGVDPSDGATGASRGKAHADYTRFLDVDGLKGARIGVPRERFFGYHPA
TDALVEEALALMKSRGAILVDPAPIPAVAQVDAPELEVLLYEFKAGLEAYLATLEEGTAPRTLAELIRYNEAHAPSELPY
FGQELFHMAQAKGPLTDKAYLKALQACRRLSRAQGLDAVMKKHQLDALVAPTQAPVGLIDPINGDHWLGSSSTPAAVSGY
ASITVPAGFVYGLPVGLSFIGGAWSEPVLLKLAHAYEHASKHRRPPTFAETADLRVHAGAGSPPAKP

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=519, Percent_Identity=28.7090558766859, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI195972892, Length=268, Percent_Identity=29.8507462686567, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17543272, Length=444, Percent_Identity=25.6756756756757, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17556264, Length=238, Percent_Identity=29.8319327731092, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17537465, Length=235, Percent_Identity=28.5106382978723, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319685, Length=432, Percent_Identity=27.0833333333333, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6323950, Length=265, Percent_Identity=29.0566037735849, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24648113, Length=524, Percent_Identity=27.8625954198473, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356731, Length=204, Percent_Identity=34.3137254901961, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644968, Length=256, Percent_Identity=28.90625, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648435, Length=287, Percent_Identity=29.9651567944251, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24648437, Length=287, Percent_Identity=29.9651567944251, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45550774, Length=287, Percent_Identity=29.9651567944251, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648441, Length=301, Percent_Identity=27.5747508305648, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648439, Length=301, Percent_Identity=27.5747508305648, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24652985, Length=244, Percent_Identity=29.9180327868852, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19922090, Length=244, Percent_Identity=29.9180327868852, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24652981, Length=244, Percent_Identity=29.9180327868852, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24652983, Length=244, Percent_Identity=29.9180327868852, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161078093, Length=259, Percent_Identity=30.1158301158301, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 57106; Mature: 56975

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSRRTVLRGTAAATALASLDVPAHAAPTPARPFELAEATVVDLQAAMKAGELTAQGLA
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERYLARIADWDSRGRLPLRSVIELNPDALATAAALDQERREKGPRGPLHGIPVLLKDNIA
HHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
TADQMQTTAGSLALVGARPSRDAFIVERLRAAGAVILGKTNLSEWANFRSTRSASGWSAR
CHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCCCCC
GGQTRNPYALDRTPSGSSSGAGAATAANFCAVSVGTETDGSIVSPAAASALVGLKPTVGL
CCCCCCCEEECCCCCCCCCCCCHHHHHCEEEEEECCCCCCCEECCHHHHHHHCCCCCHHH
VSRSGIIPISHSQDTAGPMTRTVADAAALLSVLAGVDPSDGATGASRGKAHADYTRFLDV
HHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEC
DGLKGARIGVPRERFFGYHPATDALVEEALALMKSRGAILVDPAPIPAVAQVDAPELEVL
CCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCHHHHH
LYEFKAGLEAYLATLEEGTAPRTLAELIRYNEAHAPSELPYFGQELFHMAQAKGPLTDKA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
YLKALQACRRLSRAQGLDAVMKKHQLDALVAPTQAPVGLIDPINGDHWLGSSSTPAAVSG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCC
YASITVPAGFVYGLPVGLSFIGGAWSEPVLLKLAHAYEHASKHRRPPTFAETADLRVHAG
CEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
AGSPPAKP
CCCCCCCC
>Mature Secondary Structure 
GLSRRTVLRGTAAATALASLDVPAHAAPTPARPFELAEATVVDLQAAMKAGELTAQGLA
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERYLARIADWDSRGRLPLRSVIELNPDALATAAALDQERREKGPRGPLHGIPVLLKDNIA
HHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCC
TADQMQTTAGSLALVGARPSRDAFIVERLRAAGAVILGKTNLSEWANFRSTRSASGWSAR
CHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCCCCCC
GGQTRNPYALDRTPSGSSSGAGAATAANFCAVSVGTETDGSIVSPAAASALVGLKPTVGL
CCCCCCCEEECCCCCCCCCCCCHHHHHCEEEEEECCCCCCCEECCHHHHHHHCCCCCHHH
VSRSGIIPISHSQDTAGPMTRTVADAAALLSVLAGVDPSDGATGASRGKAHADYTRFLDV
HHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEC
DGLKGARIGVPRERFFGYHPATDALVEEALALMKSRGAILVDPAPIPAVAQVDAPELEVL
CCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCCHHHHH
LYEFKAGLEAYLATLEEGTAPRTLAELIRYNEAHAPSELPYFGQELFHMAQAKGPLTDKA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHH
YLKALQACRRLSRAQGLDAVMKKHQLDALVAPTQAPVGLIDPINGDHWLGSSSTPAAVSG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCCCC
YASITVPAGFVYGLPVGLSFIGGAWSEPVLLKLAHAYEHASKHRRPPTFAETADLRVHAG
CEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECC
AGSPPAKP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]