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The map label for this gene is mraY

Identifier: 108762428

GI number: 108762428

Start: 6970180

End: 6971358

Strand: Reverse

Name: mraY

Synonym: MXAN_5607

Alternate gene names: 108762428

Gene position: 6971358-6970180 (Counterclockwise)

Preceding gene: 108762254

Following gene: 108763559

Centisome position: 76.28

GC content: 64.97

Gene sequence:

>1179_bases
GTGCTGTACCTCCTCTACGAGGTCATCCAGAACTCCGAGGCGGGGCGCGTTCTCAACTTCCTGCGCTACCCCACCTTCCG
CATCATCGCCGCGGGCGTCTTCGCGCTCCTCCTGGGCATGCTCATCGGGCCCAAGCTCATCGCTCGGCTGCGGCTGAAGC
AGCACGGGCAGAGCAACGTGCGCGAGGACACGCCGGACTCGCACCAGAAGAAGAAGGGCACGCCCACCATGGGCGGCGCG
CTCATCCTGCTGTGCATCGCGGCGGGCACGCTGCTGTTCGCGGACCTGAAGAGCCGCGCCGTCTGGGTGATGCTGCTGCT
GACGCTGGGCTACGGCTTCATCGGCTTCCTGGATGACTGGCTCAAGCTGTCCAAGCGCAACTCCAAGGGCCTGGCCGGGC
GCAAGAAGATGGTGTTGCAGACCTTCTTCTTCCTCGTCGCCGTGTTCGGCCTGCTGACGACGTGGACGCTGCCGGACGGC
TCCTTCGGCCCCACGCTGCTCATCAATACCAAGCTGACGCTGCCCTTCATCCCCACGCGCTGGTTCAACCCGGACCTGGG
CTGGTTCTACGTCTTCTTCGCGTGGATTGTTGTCGTGGGCACGTCCAACGCGGTGAACCTCACGGACGGCCTGGATGGTC
TGGCCATCGTCCCCACCATCGTGTCCGCCATCACCTTCGCGGTGCTCTGCTACGTGGCGGGCACCACGCTGAGCATCGCG
GACTACGAGGTGGTGGGCGGCGCGTCGAAGCTGGTGGCCACGCCGCTGTACCAGTACCTGGGCATCCTCCAGGTGCCGGG
CGGCGCGGAGCTGGCGGTGTTCTGCGCGGCCATCGTCGGTGCGGGCATCTCGTTCCTGTGGTTCAACACCTACCCGGCCT
CCGTCTTCATGGGCGACATCGGCTCGCTGGCCCTGGGCGGCGCGCTGGGCGGGCTGGCGATGCTGTCCAAGAACGAGGTG
GTGTCCGCCATCATCCACGGCATCTTCTTCGCCGAAATCCTGAGCGTGATGATTCAGGTCACGTCCTTCAAGATGACGGG
CAAGCGCGTCTTCAAGATGGCGCCGGTGCACCATCACTTCGAGCTCAAAGGGATGGCCGAGCCGAAGATCATCGTCCGTT
TCTGGATCGTCTCCATCCTCTGTGGTGGCGTGGCGCTCCTGTCCCTGAAGCTCCGCTGA

Upstream 100 bases:

>100_bases
GCGAAGGTGACGTGGTGCTGGTGAAGGGCAGCCGCGGCATGCGGCTGGAGCGGGTGGTGGCCGCCCTGACGGGCACGGCC
GCCCCCGGAGGAAACCACTA

Downstream 100 bases:

>100_bases
AGCCGGAGGTGGCACGGCCATGACGTTGGCGCTGTCCGGTCAGAAGGTGCTGGTGTTCGGGCTCGCGAAGAGCGGCGTGG
CCGCGCTGCGCCTGCTGCGT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MLYLLYEVIQNSEAGRVLNFLRYPTFRIIAAGVFALLLGMLIGPKLIARLRLKQHGQSNVREDTPDSHQKKKGTPTMGGA
LILLCIAAGTLLFADLKSRAVWVMLLLTLGYGFIGFLDDWLKLSKRNSKGLAGRKKMVLQTFFFLVAVFGLLTTWTLPDG
SFGPTLLINTKLTLPFIPTRWFNPDLGWFYVFFAWIVVVGTSNAVNLTDGLDGLAIVPTIVSAITFAVLCYVAGTTLSIA
DYEVVGGASKLVATPLYQYLGILQVPGGAELAVFCAAIVGAGISFLWFNTYPASVFMGDIGSLALGGALGGLAMLSKNEV
VSAIIHGIFFAEILSVMIQVTSFKMTGKRVFKMAPVHHHFELKGMAEPKIIVRFWIVSILCGGVALLSLKLR

Sequences:

>Translated_392_residues
MLYLLYEVIQNSEAGRVLNFLRYPTFRIIAAGVFALLLGMLIGPKLIARLRLKQHGQSNVREDTPDSHQKKKGTPTMGGA
LILLCIAAGTLLFADLKSRAVWVMLLLTLGYGFIGFLDDWLKLSKRNSKGLAGRKKMVLQTFFFLVAVFGLLTTWTLPDG
SFGPTLLINTKLTLPFIPTRWFNPDLGWFYVFFAWIVVVGTSNAVNLTDGLDGLAIVPTIVSAITFAVLCYVAGTTLSIA
DYEVVGGASKLVATPLYQYLGILQVPGGAELAVFCAAIVGAGISFLWFNTYPASVFMGDIGSLALGGALGGLAMLSKNEV
VSAIIHGIFFAEILSVMIQVTSFKMTGKRVFKMAPVHHHFELKGMAEPKIIVRFWIVSILCGGVALLSLKLR
>Mature_392_residues
MLYLLYEVIQNSEAGRVLNFLRYPTFRIIAAGVFALLLGMLIGPKLIARLRLKQHGQSNVREDTPDSHQKKKGTPTMGGA
LILLCIAAGTLLFADLKSRAVWVMLLLTLGYGFIGFLDDWLKLSKRNSKGLAGRKKMVLQTFFFLVAVFGLLTTWTLPDG
SFGPTLLINTKLTLPFIPTRWFNPDLGWFYVFFAWIVVVGTSNAVNLTDGLDGLAIVPTIVSAITFAVLCYVAGTTLSIA
DYEVVGGASKLVATPLYQYLGILQVPGGAELAVFCAAIVGAGISFLWFNTYPASVFMGDIGSLALGGALGGLAMLSKNEV
VSAIIHGIFFAEILSVMIQVTSFKMTGKRVFKMAPVHHHFELKGMAEPKIIVRFWIVSILCGGVALLSLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=392, Percent_Identity=44.3877551020408, Blast_Score=287, Evalue=9e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_MYXXD (Q1D0S7)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633746.1
- STRING:   Q1D0S7
- GeneID:   4106178
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_5607
- TIGR:   MXAN_5607
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q1D0S7
- ProtClustDB:   PRK00108
- BioCyc:   MXAN246197:MXAN_5607-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 42590; Mature: 42590

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x186e6d58)-; HASH(0x175c0e40)-; HASH(0x175b5088)-; HASH(0x17919500)-; HASH(0x1791932c)-; HASH(0x17cabc1c)-; HASH(0x17cabb98)-; HASH(0x178ed16c)-; HASH(0x17919590)-; HASH(0x175c1020)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLLYEVIQNSEAGRVLNFLRYPTFRIIAAGVFALLLGMLIGPKLIARLRLKQHGQSNV
CHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
REDTPDSHQKKKGTPTMGGALILLCIAAGTLLFADLKSRAVWVMLLLTLGYGFIGFLDDW
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLSKRNSKGLAGRKKMVLQTFFFLVAVFGLLTTWTLPDGSFGPTLLINTKLTLPFIPTR
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCC
WFNPDLGWFYVFFAWIVVVGTSNAVNLTDGLDGLAIVPTIVSAITFAVLCYVAGTTLSIA
CCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
DYEVVGGASKLVATPLYQYLGILQVPGGAELAVFCAAIVGAGISFLWFNTYPASVFMGDI
CCHHHCCCHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHCCH
GSLALGGALGGLAMLSKNEVVSAIIHGIFFAEILSVMIQVTSFKMTGKRVFKMAPVHHHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
ELKGMAEPKIIVRFWIVSILCGGVALLSLKLR
EECCCCCCHHHHHHHHHHHHHHHHHHHHEECH
>Mature Secondary Structure
MLYLLYEVIQNSEAGRVLNFLRYPTFRIIAAGVFALLLGMLIGPKLIARLRLKQHGQSNV
CHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
REDTPDSHQKKKGTPTMGGALILLCIAAGTLLFADLKSRAVWVMLLLTLGYGFIGFLDDW
CCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLSKRNSKGLAGRKKMVLQTFFFLVAVFGLLTTWTLPDGSFGPTLLINTKLTLPFIPTR
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCC
WFNPDLGWFYVFFAWIVVVGTSNAVNLTDGLDGLAIVPTIVSAITFAVLCYVAGTTLSIA
CCCCCHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEE
DYEVVGGASKLVATPLYQYLGILQVPGGAELAVFCAAIVGAGISFLWFNTYPASVFMGDI
CCHHHCCCHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHCCH
GSLALGGALGGLAMLSKNEVVSAIIHGIFFAEILSVMIQVTSFKMTGKRVFKMAPVHHHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
ELKGMAEPKIIVRFWIVSILCGGVALLSLKLR
EECCCCCCHHHHHHHHHHHHHHHHHHHHEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA