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The map label for this gene is lytS [H]

Identifier: 108761283

GI number: 108761283

Start: 1495604

End: 1496665

Strand: Reverse

Name: lytS [H]

Synonym: MXAN_1280

Alternate gene names: 108761283

Gene position: 1496665-1495604 (Counterclockwise)

Preceding gene: 108760047

Following gene: 108758032

Centisome position: 16.38

GC content: 73.16

Gene sequence:

>1062_bases
ATGCTGGAAACAACGGAAGGCTCCATCGTCCGCGCCACCCTGCGGGCCCTCGTGGAGCCCCGACGGCTGCTGCCCATCCT
CGTCATCTCCGTCGCGCTGATTACCGCGCAGGTGCGCTTCAGCCACGCCCCCCTCTGGGCCGCGTTCGGGCTGGGCCTCT
TGATGTGCCTGCTCTTCATCGCGGTGGCCCCAGTCTCCTACCGCGTCCTCTTCCCGGAGGGCCTGGACCTCAGCCATGGC
GGCATCCGGCTCCTGCTCTACGCCACCGTGGGCAGCGGCGTGGTGCTCACCTCCGGCTTCGTGCTGCCGAAGCTCCTGGG
CATGGGCCCCACCTTCCTCACGCAGCCCACCAACCTCGCGGTGTGCGGCGCGCTCTTCCTCGTGGGGGGCTGGGGCCTGG
GCCGTGACATCGGCTTCGAGGAGAGCCTCACCCGCGAGCGCGCCCGCGCCGCCCGCTTCGCGCTGGAGGCCGAGCAGGCC
CAGCTCCTCGCGCTGCGCAGCCACCTGGACCCGCACTTCCTCTTCAACACGCTCAACGCCATCGCGGAGTGGTGCCGTGA
GGACGGCGCCGTCGCGGAGACCGCCGTGCTGCGGCTGTCCACCATGCTCCGCTCCGTGCTCGCGGGCGTGCGCAGCGCCA
CCTGGCCCCTGGCCCAGGAGCTGGAGCTCATCCGCACGCTCTTCGACCTGCACCTGCTCCGCGACCCGGACCTCTTCCAA
CTCACGCTGAACATCCCCGCCGGCATGGAGGAGATTCCCGTCCCGCCGCTCGTGCTGCTCCCCCTGGCGGAGAACGCGGT
GAAGCATGGCCCCGCCGCCGGCCACCGCGGCCCCCTGTCCCTGGACGTCACCGCGCGGGGACACGAGGTGGAGGTCGCCA
TCGAGAACCCGGGCCCCTCCCGGGGGCCGCGCGAGGGCAGCGCGGGCCTGCCCACCGTGGAGCGCCGCCTCGCCCTGGCC
TACGGCGGCGCCGCCCGCCTCGTGCTCGACGGCGGCGAGGCGCGCACCCGTGTCACCGTCACCCTGCCCCGCGCGGGCCC
CCAACCTGGAGTCCTCACCTGA

Upstream 100 bases:

>100_bases
GTCGTCCTCGCCGGCAGCATGCTGCTGGACGCCTTCGAGACGGAGCTGGAGGAGCGCCCGGCGCAGTGACGCGGCCGGCG
GTGTAGGCTCCCGCTGGCGC

Downstream 100 bases:

>100_bases
GCGCCCCACTTCGCGTCCTCATCGCCGATGACGAACTGCTCGCCCGAAAGCGCCTGACGCGGCTGCTCGCGGCGCTCCCG
GACACGGAGGTCTGCGGCGA

Product: histidine kinase family protein

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLETTEGSIVRATLRALVEPRRLLPILVISVALITAQVRFSHAPLWAAFGLGLLMCLLFIAVAPVSYRVLFPEGLDLSHG
GIRLLLYATVGSGVVLTSGFVLPKLLGMGPTFLTQPTNLAVCGALFLVGGWGLGRDIGFEESLTRERARAARFALEAEQA
QLLALRSHLDPHFLFNTLNAIAEWCREDGAVAETAVLRLSTMLRSVLAGVRSATWPLAQELELIRTLFDLHLLRDPDLFQ
LTLNIPAGMEEIPVPPLVLLPLAENAVKHGPAAGHRGPLSLDVTARGHEVEVAIENPGPSRGPREGSAGLPTVERRLALA
YGGAARLVLDGGEARTRVTVTLPRAGPQPGVLT

Sequences:

>Translated_353_residues
MLETTEGSIVRATLRALVEPRRLLPILVISVALITAQVRFSHAPLWAAFGLGLLMCLLFIAVAPVSYRVLFPEGLDLSHG
GIRLLLYATVGSGVVLTSGFVLPKLLGMGPTFLTQPTNLAVCGALFLVGGWGLGRDIGFEESLTRERARAARFALEAEQA
QLLALRSHLDPHFLFNTLNAIAEWCREDGAVAETAVLRLSTMLRSVLAGVRSATWPLAQELELIRTLFDLHLLRDPDLFQ
LTLNIPAGMEEIPVPPLVLLPLAENAVKHGPAAGHRGPLSLDVTARGHEVEVAIENPGPSRGPREGSAGLPTVERRLALA
YGGAARLVLDGGEARTRVTVTLPRAGPQPGVLT
>Mature_353_residues
MLETTEGSIVRATLRALVEPRRLLPILVISVALITAQVRFSHAPLWAAFGLGLLMCLLFIAVAPVSYRVLFPEGLDLSHG
GIRLLLYATVGSGVVLTSGFVLPKLLGMGPTFLTQPTNLAVCGALFLVGGWGLGRDIGFEESLTRERARAARFALEAEQA
QLLALRSHLDPHFLFNTLNAIAEWCREDGAVAETAVLRLSTMLRSVLAGVRSATWPLAQELELIRTLFDLHLLRDPDLFQ
LTLNIPAGMEEIPVPPLVLLPLAENAVKHGPAAGHRGPLSLDVTARGHEVEVAIENPGPSRGPREGSAGLPTVERRLALA
YGGAARLVLDGGEARTRVTVTLPRAGPQPGVLT

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=192, Percent_Identity=30.2083333333333, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788446, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37776; Mature: 37776

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETTEGSIVRATLRALVEPRRLLPILVISVALITAQVRFSHAPLWAAFGLGLLMCLLFI
CCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVAPVSYRVLFPEGLDLSHGGIRLLLYATVGSGVVLTSGFVLPKLLGMGPTFLTQPTNLA
HHCCCEEEEECCCCCCCCCCCEEEEEEEECCCCEEEECCHHHHHHHCCCCCCEECCCCHH
VCGALFLVGGWGLGRDIGFEESLTRERARAARFALEAEQAQLLALRSHLDPHFLFNTLNA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAEWCREDGAVAETAVLRLSTMLRSVLAGVRSATWPLAQELELIRTLFDLHLLRDPDLFQ
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
LTLNIPAGMEEIPVPPLVLLPLAENAVKHGPAAGHRGPLSLDVTARGHEVEVAIENPGPS
EEEECCCCCCCCCCCCEEEEECHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCC
RGPREGSAGLPTVERRLALAYGGAARLVLDGGEARTRVTVTLPRAGPQPGVLT
CCCCCCCCCCCHHHHHHHHEECCEEEEEEECCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MLETTEGSIVRATLRALVEPRRLLPILVISVALITAQVRFSHAPLWAAFGLGLLMCLLFI
CCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AVAPVSYRVLFPEGLDLSHGGIRLLLYATVGSGVVLTSGFVLPKLLGMGPTFLTQPTNLA
HHCCCEEEEECCCCCCCCCCCEEEEEEEECCCCEEEECCHHHHHHHCCCCCCEECCCCHH
VCGALFLVGGWGLGRDIGFEESLTRERARAARFALEAEQAQLLALRSHLDPHFLFNTLNA
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAEWCREDGAVAETAVLRLSTMLRSVLAGVRSATWPLAQELELIRTLFDLHLLRDPDLFQ
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
LTLNIPAGMEEIPVPPLVLLPLAENAVKHGPAAGHRGPLSLDVTARGHEVEVAIENPGPS
EEEECCCCCCCCCCCCEEEEECHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEECCCCCC
RGPREGSAGLPTVERRLALAYGGAARLVLDGGEARTRVTVTLPRAGPQPGVLT
CCCCCCCCCCCHHHHHHHHEECCEEEEEEECCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA