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The map label for this gene is groES

Identifier: 108759998

GI number: 108759998

Start: 6125521

End: 6125811

Strand: Direct

Name: groES

Synonym: MXAN_4894

Alternate gene names: 108759998

Gene position: 6125521-6125811 (Clockwise)

Preceding gene: 108758122

Following gene: 108762020

Centisome position: 67.02

GC content: 62.2

Gene sequence:

>291_bases
ATGAAGATTCGTCCCCTGCAGGATCGGCTCATCGTCAAGCGCGTCGCCGAGGAGAACAAGACCAAGGGCGGCCTCTTCAT
CCCCGACACGGCGAAGGAGAAGCCCCTCGAGGGCAAGGTCATCGCCGTGGGCAACGGCAAGGTGCAGGAGGACGGCAAGG
TCCGTCCGCTGGACATCAAGGCCGGCGACACCATCCTGTTCAGCAAGTACGCGGGCACCGAGATCAAGCTCGACGGCGAG
GAGCACCTCATCCTCCGTGAAGAGGATGTGCTCGGCGTGATCGAGAAGTAA

Upstream 100 bases:

>100_bases
GAGTGCTAACCCCATGGGTCGCGAGGCCCTTTTTCAACCCCCAAGCAGCTTTCGGTTGCCAACGGAAACGGCGCCGGAAG
CGACATGTAAGGAGCAGGCC

Downstream 100 bases:

>100_bases
TCCGGCTTCCCCCACTCTTCCTTCAAGGAACCATCCAAATGGCGAAGGACATTCTTTTCGACGTGCGCGCGCGTGAGGCC
ATCCTCCGCGGCGTCAACAT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKIRPLQDRLIVKRVAEENKTKGGLFIPDTAKEKPLEGKVIAVGNGKVQEDGKVRPLDIKAGDTILFSKYAGTEIKLDGE
EHLILREEDVLGVIEK

Sequences:

>Translated_96_residues
MKIRPLQDRLIVKRVAEENKTKGGLFIPDTAKEKPLEGKVIAVGNGKVQEDGKVRPLDIKAGDTILFSKYAGTEIKLDGE
EHLILREEDVLGVIEK
>Mature_96_residues
MKIRPLQDRLIVKRVAEENKTKGGLFIPDTAKEKPLEGKVIAVGNGKVQEDGKVRPLDIKAGDTILFSKYAGTEIKLDGE
EHLILREEDVLGVIEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=39.5604395604396, Blast_Score=73, Evalue=5e-14,
Organism=Homo sapiens, GI169210012, Length=91, Percent_Identity=36.2637362637363, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=46.875, Blast_Score=92, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=41.9354838709677, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=97, Percent_Identity=38.1443298969072, Blast_Score=63, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=39.1752577319588, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_MYXXD (Q1D2S2)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633051.1
- ProteinModelPortal:   Q1D2S2
- SMR:   Q1D2S2
- STRING:   Q1D2S2
- GeneID:   4103338
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4894
- TIGR:   MXAN_4894
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   TEVELDG
- PhylomeDB:   Q1D2S2
- ProtClustDB:   PRK00364
- BioCyc:   MXAN246197:MXAN_4894-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10651; Mature: 10651

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRPLQDRLIVKRVAEENKTKGGLFIPDTAKEKPLEGKVIAVGNGKVQEDGKVRPLDIK
CCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCEEEEEECCEECCCCCEEEEEEC
AGDTILFSKYAGTEIKLDGEEHLILREEDVLGVIEK
CCCEEEEEECCCCEEEECCCCEEEEECCCEEEEECC
>Mature Secondary Structure
MKIRPLQDRLIVKRVAEENKTKGGLFIPDTAKEKPLEGKVIAVGNGKVQEDGKVRPLDIK
CCCCCCHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCEEEEEECCEECCCCCEEEEEEC
AGDTILFSKYAGTEIKLDGEEHLILREEDVLGVIEK
CCCEEEEEECCCCEEEECCCCEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA