BacMap

Definition	Helicobacter pylori HPAG1 chromosome, complete genome.
Accession	NC_008086
Length	1,596,366

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The map label for this gene is ydfG [C]

Identifier: 108563460

GI number: 108563460

Start: 1089671

End: 1090423

Strand: Direct

Name: ydfG [C]

Synonym: HPAG1_1035

Alternate gene names: 108563460

Gene position: 1089671-1090423 (Clockwise)

Preceding gene: 108563459

Following gene: 108563464

Centisome position: 68.26

GC content: 43.03

Gene sequence:

>753_bases
ATGGCACACATTTTAGTTAGCGGGGCGACTTCAGGGTTTGGGTTAGAAATCGCTAAAGCGTTTTTACAAAAAAACCATGT
GGTTTTTGGCACAGGGAGGCGAAAAGGGAATTTGCAAGAATTACAGCTCGCTTATCCCAAGCATTTCATTCCCCTGTGTT
TTGATCTTAAAAACAAGCTTGAAACTAAGCGGGCGATAGAAACTATTTTTTCCATGACGGATCGCATTGACGCTTTAATC
AATAACGCCGGCTTAGCGCTAGGCTTAAACAAGGCTTATGAATGCGAGCTAGACGATTGGGAAATCATGATAGACACGAA
TATCAAGGGGTTGTTGTATCTCACTCGTTTGATCTTGCCCTCTATGATAGAACATAACCAAGGGACTATCATCAATCTTG
GCTCTATCGCTGGCACTTACGCCTATCCTGGAGGGAATGTCTATGGAGCGAGCAAGGCGTTTGTGAAACAATTTTCTTTA
AATTTGCGAGCGGATTTGGCTGGCACTAACATTAGAGTGAGCAATGTTGAACCCGGTTTGTGTGGCGAAACCGAATTCAG
CATGGTGCGCTTTAAAGGCGATAAGATAAAAGCCCAATCCGTCTATGAAAACACCATTTACCTCAAACCACAAGATATTG
CTAACATCGTGCTATGGATTTACGAACAACCCTTGCATGTCAATATCAACCGCATAGAAATCATGCCCATAAGCCAAACT
TTCGCTCCCCTACCCACCCATAAAAAACCTTAA

Upstream 100 bases:

>100_bases
AAAAAAAGGTTTAGACCATTTGCTTAAAGATGATAAGCTCAAAGAAAAGCTTGAAAAAGGGCTTAAGGGGCTTTTTTAAC
CCTAATTTTAAAGGATAGAA

Downstream 100 bases:

>100_bases
GGGGTTTTAAGAATAAATTTAAACTTTAACAACCCTTTAATTTATCTTCAAAAAAAAGGGGGTTTTGGTTATTTTATTTT
AAACTCACTATTTTAATGGG

Product: short chain alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKGNLQELQLAYPKHFIPLCFDLKNKLETKRAIETIFSMTDRIDALI
NNAGLALGLNKAYECELDDWEIMIDTNIKGLLYLTRLILPSMIEHNQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSL
NLRADLAGTNIRVSNVEPGLCGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
FAPLPTHKKP

Sequences:

>Translated_250_residues
MAHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKGNLQELQLAYPKHFIPLCFDLKNKLETKRAIETIFSMTDRIDALI
NNAGLALGLNKAYECELDDWEIMIDTNIKGLLYLTRLILPSMIEHNQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSL
NLRADLAGTNIRVSNVEPGLCGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
FAPLPTHKKP
>Mature_249_residues
AHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKGNLQELQLAYPKHFIPLCFDLKNKLETKRAIETIFSMTDRIDALIN
NAGLALGLNKAYECELDDWEIMIDTNIKGLLYLTRLILPSMIEHNQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSLN
LRADLAGTNIRVSNVEPGLCGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQTF
APLPTHKKP

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=33.739837398374, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=31.3829787234043, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7706318, Length=271, Percent_Identity=29.1512915129151, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI32483357, Length=227, Percent_Identity=26.431718061674, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI40548397, Length=180, Percent_Identity=29.4444444444444, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI214010158, Length=180, Percent_Identity=29.4444444444444, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI214010156, Length=180, Percent_Identity=29.4444444444444, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI22758144, Length=180, Percent_Identity=29.4444444444444, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4758504, Length=234, Percent_Identity=26.0683760683761, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=28.8770053475936, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI19923817, Length=185, Percent_Identity=26.4864864864865, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22507405, Length=179, Percent_Identity=27.9329608938547, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=246, Percent_Identity=50.8130081300813, Blast_Score=274, Evalue=5e-75,
Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=26.3374485596708, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787335, Length=234, Percent_Identity=27.3504273504274, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1786701, Length=179, Percent_Identity=28.4916201117318, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082100, Length=178, Percent_Identity=29.2134831460674, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=187, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=186, Percent_Identity=31.1827956989247, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=25.7261410788382, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=243, Percent_Identity=26.3374485596708, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=237, Percent_Identity=23.6286919831224, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=185, Percent_Identity=29.1891891891892, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=221, Percent_Identity=25.3393665158371, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=194, Percent_Identity=25.7731958762887, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=240, Percent_Identity=26.25, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=237, Percent_Identity=26.5822784810127, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=185, Percent_Identity=26.4864864864865, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=246, Percent_Identity=24.390243902439, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=34.6938775510204, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322227, Length=185, Percent_Identity=25.9459459459459, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6322226, Length=180, Percent_Identity=25.5555555555556, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322067, Length=183, Percent_Identity=27.8688524590164, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358495, Length=225, Percent_Identity=29.7777777777778, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI23397609, Length=178, Percent_Identity=27.5280898876405, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=24.7011952191235, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281364494, Length=250, Percent_Identity=25.6, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571526, Length=181, Percent_Identity=30.3867403314917, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24643142, Length=175, Percent_Identity=30.2857142857143, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=181, Percent_Identity=29.2817679558011, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641232, Length=254, Percent_Identity=29.5275590551181, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=28.4, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=181, Percent_Identity=27.6243093922652, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28571387, Length=250, Percent_Identity=27.2, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24648693, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355889, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24663911, Length=253, Percent_Identity=25.296442687747, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=28.6324786324786, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=30.6010928961749, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=30.6010928961749, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=29.1891891891892, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=29.1891891891892, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007234, Length=251, Percent_Identity=25.4980079681275, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640442, Length=119, Percent_Identity=32.7731092436975, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27883; Mature: 27752

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKGNLQELQLAYPKHFIPLCFDLKNKL
CCEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHEECCCCCHHHHHHHHHHHH
ETKRAIETIFSMTDRIDALINNAGLALGLNKAYECELDDWEIMIDTNIKGLLYLTRLILP
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCEEEEEECCCHHHHHHHHHHHH
SMIEHNQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSLNLRADLAGTNIRVSNVEPGL
HHHHCCCCCEEEECCCCCEEECCCCCEECCHHHHHHHHCCCEEEEECCCEEEEECCCCCC
CGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
CCCCCEEEEEEECCEEEEEEEECCEEEECCHHHHEEEEEEECCCEEEEEEEEEEEECHHC
FAPLPTHKKP
CCCCCCCCCC
>Mature Secondary Structure 
AHILVSGATSGFGLEIAKAFLQKNHVVFGTGRRKGNLQELQLAYPKHFIPLCFDLKNKL
CEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCHHHHEECCCCCHHHHHHHHHHHH
ETKRAIETIFSMTDRIDALINNAGLALGLNKAYECELDDWEIMIDTNIKGLLYLTRLILP
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCEEEEEECCCHHHHHHHHHHHH
SMIEHNQGTIINLGSIAGTYAYPGGNVYGASKAFVKQFSLNLRADLAGTNIRVSNVEPGL
HHHHCCCCCEEEECCCCCEEECCCCCEECCHHHHHHHHCCCEEEEECCCEEEEECCCCCC
CGETEFSMVRFKGDKIKAQSVYENTIYLKPQDIANIVLWIYEQPLHVNINRIEIMPISQT
CCCCCEEEEEEECCEEEEEEEECCEEEECCHHHHEEEEEEECCCEEEEEEEEEEEECHHC
FAPLPTHKKP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]