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The map label for this gene is hup [H]

Identifier: 108563246

GI number: 108563246

Start: 855640

End: 855924

Strand: Direct

Name: hup [H]

Synonym: HPAG1_0821

Alternate gene names: 108563246

Gene position: 855640-855924 (Clockwise)

Preceding gene: 108563245

Following gene: 108563247

Centisome position: 53.6

GC content: 41.4

Gene sequence:

>285_bases
ATGAACAAAGCGGAATTTATTGATTTGGTTAAAGAAGCGGGTAAATACAGCAGCAAAAGAGAAGCCGAAGAAGCGATCAG
TGCCTTTACTCTAGCGGTAGAAACAGCTTTAAGCAAGGGTGAGAGCGTGGAGTTGGTTGGTTTTGGTAAATTTGAAACCG
CAGAGCAAAAAGGCAAAGAGGGTAAAGTGCCAGGAAGCGATAAAACTTATAAAACCGAAGACAAGCGAGTGCCTAAATTC
AAACCCGGTAAAATCCTTAAACAAAAAGTTGAAGAAGGCAAGTGA

Upstream 100 bases:

>100_bases
TGATTTATCTTTAGGATTTGATTATAATTACCGCTCAATCAGTCAAGCTAGGCGATTAAATCGCTTGGTTTTGTCATCTA
TTAGAAAAGGGGTTATCCAC

Downstream 100 bases:

>100_bases
GTCTGATTTACTCAGCAAGGGGCTTATCAATAAGGTTTCTTGCTTTTTTATAAAATGTCCTTGTAGCTCAGCTGGATAGA
GCGTATGATTCCTAATCGTA

Product: DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MNKAEFIDLVKEAGKYSSKREAEEAISAFTLAVETALSKGESVELVGFGKFETAEQKGKEGKVPGSDKTYKTEDKRVPKF
KPGKILKQKVEEGK

Sequences:

>Translated_94_residues
MNKAEFIDLVKEAGKYSSKREAEEAISAFTLAVETALSKGESVELVGFGKFETAEQKGKEGKVPGSDKTYKTEDKRVPKF
KPGKILKQKVEEGK
>Mature_94_residues
MNKAEFIDLVKEAGKYSSKREAEEAISAFTLAVETALSKGESVELVGFGKFETAEQKGKEGKVPGSDKTYKTEDKRVPKF
KPGKILKQKVEEGK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=91, Percent_Identity=37.3626373626374, Blast_Score=59, Evalue=6e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10355; Mature: 10355

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAEFIDLVKEAGKYSSKREAEEAISAFTLAVETALSKGESVELVGFGKFETAEQKGKE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCC
GKVPGSDKTYKTEDKRVPKFKPGKILKQKVEEGK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNKAEFIDLVKEAGKYSSKREAEEAISAFTLAVETALSKGESVELVGFGKFETAEQKGKE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHCCCC
GKVPGSDKTYKTEDKRVPKFKPGKILKQKVEEGK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]