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The map label for this gene is engA [H]

Identifier: 108563245

GI number: 108563245

Start: 854113

End: 855498

Strand: Direct

Name: engA [H]

Synonym: HPAG1_0820

Alternate gene names: 108563245

Gene position: 854113-855498 (Clockwise)

Preceding gene: 108563237

Following gene: 108563246

Centisome position: 53.5

GC content: 39.97

Gene sequence:

>1386_bases
ATGAATACAAGCCATAAAACTTTAAAAACCATTGCGATTTTAGGCCAGCCTAATGTGGGGAAAAGCTCGCTATTTAACCG
CTTAGCTAGAGAAAGGATCGCTATCACTTCAGATTTTGCAGGCACTACACGAGACATTAACAAACGAAAAATCGCATTGA
ATGGCTATGAAGTGGAATTATTAGATACAGGGGGCATGGCTAAAGACGCCCTTTTGTCTAAAGAAATCAAAGCCCTTAAT
TTAAAAGCCGCTCAAATGAGCGATTTGATTTTATACGTTGTGGATGGCAAGTCTATCCCTAGCGATGAAGACATCAAGCT
TTTTAGAGAGGTTTTTAAGATCAACCCTAACTGCTTTTTAGTGATCAATAAAATTGATAACGACAAAGAAAAAGAGCGAG
CTTATGCGTTTTCTTCTTTTGGCATGCCAAAGAGTTTTAATATCTCCGTTTCGCACAATAGAGGCATTAGCGCGTTAATT
GATGCGGTATTGAGTGCGCTGAATTTAAACAAAATCATAGAGCAAGATTTGGATGCGGATATTTTAGAAAGCTTAGAAAA
TAACGCATTAGAAGAAGAAACTAAAGAAGAAGAGATCATTCAAGTAGGCATCATTGGGAGGGTGAATGTGGGCAAAAGCT
CGCTCTTAAACGCGCTCACGAAAAAAGAAAGGAGTCTTGTTTCTAGCGTGGCTGGCACGACCATTGACCCCATAGATGAA
ACCATTCTCATAGGCGATCAAAAAATCTGCTTTGTGGATACCGCTGGCATCAGGCATAGGAGTAAAATTTTAGGCATTGA
AAAATACGCGCTAGAACGCACGCAAAAAGCCTTAGAAAAATCCCACATCGCGCTTTTAGTTTTAGACGTGAGCGCTCCTT
TTGTGGAATTAGACGAAAAGATCAGCTCCTTAGCGGATAAACACTCTTTAGGGATCATTCTTATTTTAAACAAATGGGAC
ATCCGCTACGCCCCTTATGAAGAAATCATGGAAACCTTAAAAAGGAAATTCCGCTTTTTAGAATACGCCCCCGTGATCAC
AACCAGCTGCTTAAAAGCACGCCATATAGATGAAATCAAGCATAAAATCATAGAAGTCTATGAGTGTTTTTCCAAACGCA
TTCCCACGAGCTTGCTCAATAGCGTGATTTCTCAAGCCACCCAAAAACACCCCTTGCCAAGCGATGGAGGGAAATTAGTG
AAAGTGTATTACGCCACGCAATTTGCCACCAAACCCCCTCAAATCTCTCTTATCATGAATCGCCCTAAAGCCTTGCATTT
CAGTTACAAACGCTATTTGATCAACACCTTAAGGAAAGAATTTAATTTTTTAGGCACGCCTTTAATCCTTAACGCTAAAG
ATAAAAAAAGCGCTCAACAGAATTAA

Upstream 100 bases:

>100_bases
GCCTATTTTTTTGACTAAAAACAACGCTAGACCCTTATTTAAGCTTTAAATAACTATAATATTGTAATCTAATTTTGATT
AAATTGAAGCGATAAAAAAG

Downstream 100 bases:

>100_bases
ATTTTTTATGCGTTAAACCCCCTTAAAAAAGCGTTTTTGCTTGATTTATCTTTAGGATTTGATTATAATTACCGCTCAAT
CAGTCAAGCTAGGCGATTAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGYEVELLDTGGMAKDALLSKEIKALN
LKAAQMSDLILYVVDGKSIPSDEDIKLFREVFKINPNCFLVINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISALI
DAVLSALNLNKIIEQDLDADILESLENNALEEETKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
TILIGDQKICFVDTAGIRHRSKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEKISSLADKHSLGIILILNKWD
IRYAPYEEIMETLKRKFRFLEYAPVITTSCLKARHIDEIKHKIIEVYECFSKRIPTSLLNSVISQATQKHPLPSDGGKLV
KVYYATQFATKPPQISLIMNRPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN

Sequences:

>Translated_461_residues
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGYEVELLDTGGMAKDALLSKEIKALN
LKAAQMSDLILYVVDGKSIPSDEDIKLFREVFKINPNCFLVINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISALI
DAVLSALNLNKIIEQDLDADILESLENNALEEETKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
TILIGDQKICFVDTAGIRHRSKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEKISSLADKHSLGIILILNKWD
IRYAPYEEIMETLKRKFRFLEYAPVITTSCLKARHIDEIKHKIIEVYECFSKRIPTSLLNSVISQATQKHPLPSDGGKLV
KVYYATQFATKPPQISLIMNRPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN
>Mature_461_residues
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGYEVELLDTGGMAKDALLSKEIKALN
LKAAQMSDLILYVVDGKSIPSDEDIKLFREVFKINPNCFLVINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISALI
DAVLSALNLNKIIEQDLDADILESLENNALEEETKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
TILIGDQKICFVDTAGIRHRSKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEKISSLADKHSLGIILILNKWD
IRYAPYEEIMETLKRKFRFLEYAPVITTSCLKARHIDEIKHKIIEVYECFSKRIPTSLLNSVISQATQKHPLPSDGGKLV
KVYYATQFATKPPQISLIMNRPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=469, Percent_Identity=31.7697228144989, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI2367268, Length=159, Percent_Identity=36.4779874213836, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=271, Percent_Identity=28.4132841328413, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51744; Mature: 51744

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGYEVEL
CCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEECCEEEEE
LDTGGMAKDALLSKEIKALNLKAAQMSDLILYVVDGKSIPSDEDIKLFREVFKINPNCFL
EECCCCHHHHHHHHHHHHHCCCHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
VINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISALIDAVLSALNLNKIIEQDLDAD
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
ILESLENNALEEETKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
HHHHHHCCCHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TILIGDQKICFVDTAGIRHRSKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEK
EEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHH
ISSLADKHSLGIILILNKWDIRYAPYEEIMETLKRKFRFLEYAPVITTSCLKARHIDEIK
HHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKIIEVYECFSKRIPTSLLNSVISQATQKHPLPSDGGKLVKVYYATQFATKPPQISLIMN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEC
RPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MNTSHKTLKTIAILGQPNVGKSSLFNRLARERIAITSDFAGTTRDINKRKIALNGYEVEL
CCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEECCEEEEE
LDTGGMAKDALLSKEIKALNLKAAQMSDLILYVVDGKSIPSDEDIKLFREVFKINPNCFL
EECCCCHHHHHHHHHHHHHCCCHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEE
VINKIDNDKEKERAYAFSSFGMPKSFNISVSHNRGISALIDAVLSALNLNKIIEQDLDAD
EEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHH
ILESLENNALEEETKEEEIIQVGIIGRVNVGKSSLLNALTKKERSLVSSVAGTTIDPIDE
HHHHHHCCCHHHHHHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TILIGDQKICFVDTAGIRHRSKILGIEKYALERTQKALEKSHIALLVLDVSAPFVELDEK
EEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHH
ISSLADKHSLGIILILNKWDIRYAPYEEIMETLKRKFRFLEYAPVITTSCLKARHIDEIK
HHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKIIEVYECFSKRIPTSLLNSVISQATQKHPLPSDGGKLVKVYYATQFATKPPQISLIMN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEC
RPKALHFSYKRYLINTLRKEFNFLGTPLILNAKDKKSAQQN
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA