Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 108563236

GI number: 108563236

Start: 845262

End: 846197

Strand: Direct

Name: trxB [H]

Synonym: HPAG1_0811

Alternate gene names: 108563236

Gene position: 845262-846197 (Clockwise)

Preceding gene: 108563235

Following gene: 108563237

Centisome position: 52.95

GC content: 44.66

Gene sequence:

>936_bases
ATGATAGATTGTGCGATTATTGGAGGTGGTCCTGCAGGTTTGAGTGCGGGGCTTTATGCCACTAGAGGCGGTGTTAAAAA
CGCCGTTTTGTTTGAAAAAGGAATGCCTGGGGGGCAAATCACTGGCAGTAGTGAGATTGAAAACTATCCGGGCGTTAAGG
AAGTGGTGAGCGGGTTGGATTTCATGCAACCATGGCAGGAGCAGTGTTTCCGCTTTGGCTTAAAGCATGAGATGACCGCT
GTTCAAAGGGTTTCTAAAAAAGACTCTCATTTTGTTATTTTGGCAGAAGATGGCAAGACTTTTGAAGCTAAGAGCGTGAT
TATCGCTACCGGTGGTAGCCCTAAACGCACAGGCATCAAGGGCGAGTCAGAATATTGGGGTAAAGGCGTGAGCACTTGTG
CGACATGCGATGGCTTCTTTTACAAAAATAAGGAAGTAGCGGTGCTTGGTGGGGGCGATACCGCCGTAGAAGAGGCGATT
TATCTAGCCAACATCTGCAAAAAAGTCTATCTCATCCACAGAAGAGATGGTTTTAGATGTGCACCTATCACTTTAGAGCA
TGCCAAAAACAACGATAAGATTGAGTTTTTAACCCCTTATGTGGTGGAAGAAATCAAGGGCGATGCTTCTGGCGTGTCTT
CTTTAAGCATTAAAAACACAGCCACTAATGAAACAAGAGAATTGGTTGTGCCGGGGTTTTTTATTTTTGTGGGTTATGAT
GTGAATAACGCCGTGTTGAAACAAGAAGATAACTCCATGCTATGCAAATGCGATGAATACGGCTCTATAGTCGTGGATTT
TTCCATGAAAACGAATGTTCAAGGCTTGTTTGCAGCAGGGGATATTCGCATTTTTGCCCCTAAGCAAGTGGTTTGCGCTG
CAAGCGATGGTGCTACGGCAGCCTTAAGCGTGATTTCTTATTTAGAACACCATTAA

Upstream 100 bases:

>100_bases
CTTTTATTCACAAAAGATGGCGAAGTCGTCCATCAGTTGGTGGGCGTGCAAACTAAAGTTGCTTTAAAAGAGCAATTGAA
CAAACTTTTAGGCTAATAGC

Downstream 100 bases:

>100_bases
ATCAAGCTCATGACCCTAGGTTTTAGGGTTATGAGTCCTCGCTTCAAACATTCATTGGATCTTTTAAAACTTTTTTGTAG
CCGTGATGCGATTTCATTCG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFMQPWQEQCFRFGLKHEMTA
VQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAI
YLANICKKVYLIHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELVVPGFFIFVGYD
VNNAVLKQEDNSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAALSVISYLEHH

Sequences:

>Translated_311_residues
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFMQPWQEQCFRFGLKHEMTA
VQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAI
YLANICKKVYLIHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELVVPGFFIFVGYD
VNNAVLKQEDNSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAALSVISYLEHH
>Mature_311_residues
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFMQPWQEQCFRFGLKHEMTA
VQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAI
YLANICKKVYLIHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELVVPGFFIFVGYD
VNNAVLKQEDNSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAALSVISYLEHH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=36.2179487179487, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI87081763, Length=299, Percent_Identity=30.1003344481605, Blast_Score=128, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=37.2611464968153, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=36.624203821656, Blast_Score=181, Evalue=1e-46,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33512; Mature: 33512

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLD
CEEEEEECCCHHCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
FMQPWQEQCFRFGLKHEMTAVQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIK
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCC
GESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAIYLANICKKVYLIHRRDGFRC
CCHHHCCCCCCHHEECCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCCEE
APITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELVVPGFFIFVGYD
EEEEEECCCCCCCEEEECHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECEEEEEEEEC
VNNAVLKQEDNSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATA
CCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCEEEEECCEEEECCCEEEEECCCCCHH
ALSVISYLEHH
HHHHHHHHHCC
>Mature Secondary Structure
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLD
CEEEEEECCCHHCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
FMQPWQEQCFRFGLKHEMTAVQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIK
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCC
GESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAIYLANICKKVYLIHRRDGFRC
CCHHHCCCCCCHHEECCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCCEE
APITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELVVPGFFIFVGYD
EEEEEECCCCCCCEEEECHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECEEEEEEEEC
VNNAVLKQEDNSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATA
CCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCEEEEECCEEEECCCEEEEECCCCCHH
ALSVISYLEHH
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]