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The map label for this gene is lolC [H]

Identifier: 108563198

GI number: 108563198

Start: 810145

End: 811377

Strand: Direct

Name: lolC [H]

Synonym: HPAG1_0773

Alternate gene names: 108563198

Gene position: 810145-811377 (Clockwise)

Preceding gene: 108563197

Following gene: 108563199

Centisome position: 50.75

GC content: 39.82

Gene sequence:

>1233_bases
TTGCCAAATAGATCCTTAATCTTTTTCCTCATCAAGCGTTATTTGCGTTTTGATAAAAGCCAACCATTTATTAGCATCAC
CGCTTTGTTAGCTTTTTTTGGCGTGGCGGTTGGCGTGATGGTTTTGATTGTGGCTATGGCGATCATGAACGGCATGAGTA
AGGAATTTGAAAAAAAGCTTTTTGTGATGAACTACCCCTTAACGCTCTATACCACAAGCCCTTATGGGATCAGCGAAGAA
GTGGTTCAAGCTTTAGAAAAAAAGTTCCCCAATTTGCTTTTTAGCCCCTATTTGCAAACCCAAAGCCTGATTAAAAGCGC
GCATTCTATGAATGGTGGTGTGGTGTTTGGGGTTGATTTTTCTAAAGAAAGGCGCATCAATGAAGTTTTAAACGACGCTT
TAAAAAACACCAATACAAACGATCTTTTTAAAAACCCTTTTAATTTGATCGTGGGGAAAAGCTTGAGATACAGCTTGAAT
TTAGATCTCAATCAAAAAGCCGATTTGTTTTTCACCGAATTAGAGCCAACAGGCCTCACGCTCTCCCCTATCATGAAGCG
TTTTACCATAAAAGGTGATTTTGATTCAGGGCTAAAATCTTATGACATGAGCTACATGTATGCTAGCCTTCAAGCCATAA
GTGCGATCAGGAGGTTGCCCTTAGGGCTTTATGATGGGGTGCATGTCTATTCTAAAACGCCCATGAAGGATATTGAAATT
TTACGCAACGCTTTAAAAACCATCAACCACCATGGCATAGGCATTGAAGGGTGGTGGCAGCAAAACGGGAATTTTTTCTC
GGCTATGGAATTAGAAAAAAGAGCGTTATTCATTGTGCTCATGCTCATTATTTTAATGGCATCTTTGAATATTATTAGTT
CGCTTTTAATGGTGGTGATGAACAGGCGTAAAGAAATCGCCCTACTCTTTAGCATGGGGAGCAGCCAAAAAGAAATCCAA
AAAACCTTTTTTTATTTGGGCAATATCATTGGTTTAGGCGGTGTGGCGCTTGGGGTGGTTTTAGCGTTTATAAGCATGTA
TCTTTTAAGCGTGTTCCCTATTATCTCGCTCCCGGCGGATGTTTATGGCATTAACACCTTGCCTTTGGATCTGTCTTTAA
TGGATTTTATGCTCACTTTAATAGGCTCTGTGATCATCGTAGGGCTTTCTTCTTATTACCCGTCTAAAAAAGCTTCTACT
ATTGACGCTTTAAGCGTGTTAAGGAATGAATAA

Upstream 100 bases:

>100_bases
GCTTTTTCTAAAACCCCTAAAAGAAACGAGCCTTGCCCTTGTCAAAGCGGCAAAAAATACAAAGATTGTTGCGCTAAAAG
CGGGCCTAAAAAGGGCTTAT

Downstream 100 bases:

>100_bases
ATTAAAAAATTAAATAATATTGAGATTAAATAAGGCTTTGAGTGTCTGTATTTGACTGACAAAGAAAAATTTTATTCTCA
AAATTAAAAAAAACCATAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKLFVMNYPLTLYTTSPYGISEE
VVQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNTNDLFKNPFNLIVGKSLRYSLN
LDLNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYASLQAISAIRRLPLGLYDGVHVYSKTPMKDIEI
LRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVMNRRKEIALLFSMGSSQKEIQ
KTFFYLGNIIGLGGVALGVVLAFISMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIGSVIIVGLSSYYPSKKAST
IDALSVLRNE

Sequences:

>Translated_410_residues
MPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKLFVMNYPLTLYTTSPYGISEE
VVQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNTNDLFKNPFNLIVGKSLRYSLN
LDLNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYASLQAISAIRRLPLGLYDGVHVYSKTPMKDIEI
LRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVMNRRKEIALLFSMGSSQKEIQ
KTFFYLGNIIGLGGVALGVVLAFISMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIGSVIIVGLSSYYPSKKAST
IDALSVLRNE
>Mature_409_residues
PNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKLFVMNYPLTLYTTSPYGISEEV
VQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDFSKERRINEVLNDALKNTNTNDLFKNPFNLIVGKSLRYSLNL
DLNQKADLFFTELEPTGLTLSPIMKRFTIKGDFDSGLKSYDMSYMYASLQAISAIRRLPLGLYDGVHVYSKTPMKDIEIL
RNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVMNRRKEIALLFSMGSSQKEIQK
TFFYLGNIIGLGGVALGVVLAFISMYLLSVFPIISLPADVYGINTLPLDLSLMDFMLTLIGSVIIVGLSSYYPSKKASTI
DALSVLRNE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=403, Percent_Identity=23.5732009925558, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787360, Length=412, Percent_Identity=23.0582524271845, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46009; Mature: 45878

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKL
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FVMNYPLTLYTTSPYGISEEVVQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDF
EEEECCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
SKERRINEVLNDALKNTNTNDLFKNPFNLIVGKSLRYSLNLDLNQKADLFFTELEPTGLT
CHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCC
LSPIMKRFTIKGDFDSGLKSYDMSYMYASLQAISAIRRLPLGLYDGVHVYSKTPMKDIEI
HHHHHHHHEECCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHH
LRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVM
HHHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRRKEIALLFSMGSSQKEIQKTFFYLGNIIGLGGVALGVVLAFISMYLLSVFPIISLPAD
HCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VYGINTLPLDLSLMDFMLTLIGSVIIVGLSSYYPSKKASTIDALSVLRNE
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PNRSLIFFLIKRYLRFDKSQPFISITALLAFFGVAVGVMVLIVAMAIMNGMSKEFEKKL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FVMNYPLTLYTTSPYGISEEVVQALEKKFPNLLFSPYLQTQSLIKSAHSMNGGVVFGVDF
EEEECCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
SKERRINEVLNDALKNTNTNDLFKNPFNLIVGKSLRYSLNLDLNQKADLFFTELEPTGLT
CHHHHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCC
LSPIMKRFTIKGDFDSGLKSYDMSYMYASLQAISAIRRLPLGLYDGVHVYSKTPMKDIEI
HHHHHHHHEECCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHH
LRNALKTINHHGIGIEGWWQQNGNFFSAMELEKRALFIVLMLIILMASLNIISSLLMVVM
HHHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRRKEIALLFSMGSSQKEIQKTFFYLGNIIGLGGVALGVVLAFISMYLLSVFPIISLPAD
HCCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VYGINTLPLDLSLMDFMLTLIGSVIIVGLSSYYPSKKASTIDALSVLRNE
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]