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The map label for this gene is secA [H]

Identifier: 108563197

GI number: 108563197

Start: 807558

End: 810155

Strand: Direct

Name: secA [H]

Synonym: HPAG1_0772

Alternate gene names: 108563197

Gene position: 807558-810155 (Clockwise)

Preceding gene: 108563195

Following gene: 108563198

Centisome position: 50.59

GC content: 39.65

Gene sequence:

>2598_bases
ATGATAAAAGCAATCATTGGAAAAATCATTGGCACTAGAAACGATCGCTGGATCAAACAATACAAAAAACAAGTCCTAAC
TATCAACGCTTTAGAGCCTACTTATGAAAAAATGAGCGATGTTGAATTACAAAACGCTTTTGAAGAATTAAAAAAACGCG
TGCGATCCACAGAAAAAAATTTGCAAGAAAAAACCCTTTTAGAAGTCTTACCGGAAAGTTTTGCTATCACTAGAGAAGCG
AGTAAAAGGATCTTAAAGATGCGCCATTTTGATGTGCAACTCATTGGGGGCATGGTCTTAAACGATGGCAAAATCGCTGA
AATGAAAACCGGAGAGGGTAAAACTTTAGTCGCTACTTTAGCGGTGGCTTTGAACGCTTTAAAGGGCGAGAGCGTGTATG
TGGTAACCGTTAATGATTACCTAGCCCATAGGGATTCTAAAGAAATGGAGCCGTTGTATCATTTCTTAGGTTATAGCGTA
GGCACGATCACTGCGAGCGTGCGAGATGATGATGAGCGCTTAGAAATTTATTCTAAAGACATTGTTTATGGCACTAATAA
TGAATTTGGCTTTGATTATCTAAGGGATAACATGAAATATTCTTTAGAGCATAAGGTGCAAAAATCGCATGCGTTCGCCA
TTGTTGATGAAGTGGATTCCATTTTAATTGATGAAGCGAGAACCCCTTTAATCATTTCAGGGCCTGTGGATAGGCGCATG
GAAAATTACAACAAGGCTGATGAAGTCGCTAAAAGCATGCAAGTGGAAACCGATTTCACCATAGATGAAAAAAACCGCAC
GATTTTAATCACTGAAGAGGGGATTAAAAAAGCCGAAAACCTCTTTGGCGTGGATAATTTATACAAGATTGAAAACGCCG
CCTTATCGCACCATTTAGACCAGGCTTTGAAAGCGAATTACCTCTTTTTTATTGATAAAGATTATATTGTAGCCAATAAT
GAAGTGGTGATTGTAGATGAATTTACCGGCCGTTTGTCTGAGGGGAGGCGCTTTAGTGAGGGCTTGCATCAGGCTTTAGA
GGCTAAAGAGGGCGTGAGCATTAAAGAAGAGAGCCAAACCTTAGCCGATATTACTTTCCAAAATTATTTCAGGATGTTTT
CTAAACTTTCAGGCATGACAGGCACGGCTCAAACCGAAGCCACAGAATTTTTAGAAATCTATAATTTAGAAGTGGTGTCT
ATCCCTACTAATCTAGCGATCAAACGCAAAGATTTGAACGATCTCATCTATAAGAGTGAAAAAGAAAAATTTGACGCCGT
GATCCTCAAAATTAAAGAATTACACGATAAGGGTCAGCCCGTTCTAGTTGGCACGGCTAGCATTGAAAAGAGTGAAACCT
TGCACGCTTTACTCAAAAAAGAACGCATCCCTCACACCGTTTTAAACGCCAAGCAGCACACCAAAGAAGCTGAAATCATC
AAAGACGCTGGGCTTAAAGGGGCGGTTACGATTGCGACTAACATGGCAGGGAGGGGCGTTGATATTAAACTCACCGATGA
AATTAAAGAGCTTGGGGGGTTATATATCATTGGCACTGAAAGGCATGAGAGCCGCAGGATTGATAACCAATTAAGGGGGC
GAAGCGGGCGCCAAGGCGATCCGGGAACAAGCCAATTTTATTTGAGTTTAGAAGACAATCTGTTACGCATTTTTGGGAGC
GATAGGATTAAGGGGGTGATGGAAAAATTAGGGCTTAAAGACGGCGAACACATTGAATCCAAGCTTGTTACAAGAGCGGT
GGAAAACGCGCAAAAAAAAGTGGAAAACTTGCATTTTGAAAGCCGTAAGCATTTGTTAGAATACGATGATGTGGCTAATG
AGCAACGAAAAAGCGTGTATAAATTTAGAGATGAATTATTAGACATCAATTACGATATTAGCGCTAAAATCGCTGAAAAC
AGAGAATACGCGCTCAATCAAATCTTTTCTAAACTCAAAGCCTTTGACCATCAAAACCTGTCTGAAGAGGAACTTTTAGG
GCTTAAAAACGTCTTAAAAGAAGATTTTAACGCTCATGTTGAATTAGAGGATTTAGAAAAAGCCTCCCCTATTGAAAAAT
TTGTGGCTGAAAAACTCAAAAGCGATTATGAAAACAAAATGAAAGTTTTGGATAGCGAGCAAAGAAGCCGGATTGAACGC
ATCGTGTATTTGCAGATTTTAGACAACGCATGGCGAGAGCACCTTTATACGATGGATAATCTCAAAACCGGTATCAATTT
AAGAGGCTATAACCAAAAAGACCCTCTCGTAGAATACAAAAAAGAGAGTTACAACCTTTTCTTAGAATTCATTGAAGACA
TTAAAATAGAAGCGATCAAAACCTTTTCTAAGATCCAGTTTGAAAATGAGCAAGATTCTAGCGATGCCGAGCGTTATTTG
GATAACTTTAGCGAAGAAAGAGAGCATGAGAGCGTAACTTACCGCCATGAAGAAACTTTAGATGAAGATTTGAATGTGGC
CATGAAAGCTTTTTCTAAAACCCCTAAAAGAAACGAGCCTTGCCCTTGTCAAAGCGGCAAAAAATACAAAGATTGTTGCG
CTAAAAGCGGGCCTAAAAAGGGCTTATTTGCCAAATAG

Upstream 100 bases:

>100_bases
TTACAAGACTTTTATTTTATCCATGCTAAAATGGGATTAAAAACTGACGCTTTAATCAAATAAATAAGATTAAAGCACTC
TTAATAAGGTTATCACTACT

Downstream 100 bases:

>100_bases
ATCCTTAATCTTTTTCCTCATCAAGCGTTATTTGCGTTTTGATAAAAGCCAACCATTTATTAGCATCACCGCTTTGTTAG
CTTTTTTTGGCGTGGCGGTT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MIKAIIGKIIGTRNDRWIKQYKKQVLTINALEPTYEKMSDVELQNAFEELKKRVRSTEKNLQEKTLLEVLPESFAITREA
SKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATLAVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSV
GTITASVRDDDERLEIYSKDIVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM
ENYNKADEVAKSMQVETDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLDQALKANYLFFIDKDYIVANN
EVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQTLADITFQNYFRMFSKLSGMTGTAQTEATEFLEIYNLEVVS
IPTNLAIKRKDLNDLIYKSEKEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII
KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGDPGTSQFYLSLEDNLLRIFGS
DRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFESRKHLLEYDDVANEQRKSVYKFRDELLDINYDISAKIAEN
REYALNQIFSKLKAFDHQNLSEEELLGLKNVLKEDFNAHVELEDLEKASPIEKFVAEKLKSDYENKMKVLDSEQRSRIER
IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLEFIEDIKIEAIKTFSKIQFENEQDSSDAERYL
DNFSEEREHESVTYRHEETLDEDLNVAMKAFSKTPKRNEPCPCQSGKKYKDCCAKSGPKKGLFAK

Sequences:

>Translated_865_residues
MIKAIIGKIIGTRNDRWIKQYKKQVLTINALEPTYEKMSDVELQNAFEELKKRVRSTEKNLQEKTLLEVLPESFAITREA
SKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATLAVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSV
GTITASVRDDDERLEIYSKDIVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM
ENYNKADEVAKSMQVETDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLDQALKANYLFFIDKDYIVANN
EVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQTLADITFQNYFRMFSKLSGMTGTAQTEATEFLEIYNLEVVS
IPTNLAIKRKDLNDLIYKSEKEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII
KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGDPGTSQFYLSLEDNLLRIFGS
DRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFESRKHLLEYDDVANEQRKSVYKFRDELLDINYDISAKIAEN
REYALNQIFSKLKAFDHQNLSEEELLGLKNVLKEDFNAHVELEDLEKASPIEKFVAEKLKSDYENKMKVLDSEQRSRIER
IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLEFIEDIKIEAIKTFSKIQFENEQDSSDAERYL
DNFSEEREHESVTYRHEETLDEDLNVAMKAFSKTPKRNEPCPCQSGKKYKDCCAKSGPKKGLFAK
>Mature_865_residues
MIKAIIGKIIGTRNDRWIKQYKKQVLTINALEPTYEKMSDVELQNAFEELKKRVRSTEKNLQEKTLLEVLPESFAITREA
SKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATLAVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSV
GTITASVRDDDERLEIYSKDIVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM
ENYNKADEVAKSMQVETDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLDQALKANYLFFIDKDYIVANN
EVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQTLADITFQNYFRMFSKLSGMTGTAQTEATEFLEIYNLEVVS
IPTNLAIKRKDLNDLIYKSEKEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII
KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGDPGTSQFYLSLEDNLLRIFGS
DRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFESRKHLLEYDDVANEQRKSVYKFRDELLDINYDISAKIAEN
REYALNQIFSKLKAFDHQNLSEEELLGLKNVLKEDFNAHVELEDLEKASPIEKFVAEKLKSDYENKMKVLDSEQRSRIER
IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLEFIEDIKIEAIKTFSKIQFENEQDSSDAERYL
DNFSEEREHESVTYRHEETLDEDLNVAMKAFSKTPKRNEPCPCQSGKKYKDCCAKSGPKKGLFAK

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=914, Percent_Identity=48.5776805251641, Blast_Score=806, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 99270; Mature: 99270

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAIIGKIIGTRNDRWIKQYKKQVLTINALEPTYEKMSDVELQNAFEELKKRVRSTEKN
CHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQEKTLLEVLPESFAITREASKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEECCCCEEEEECCCCCHHHHHH
AVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSVGTITASVRDDDERLEIYSKD
HHHHHHHCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCHHHHEEEECCCCHHHHHEEECC
IVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM
EEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHH
ENYNKADEVAKSMQVETDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLD
HHCCHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QALKANYLFFIDKDYIVANNEVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQT
HHHHCCEEEEEECCEEEECCCEEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHH
LADITFQNYFRMFSKLSGMTGTAQTEATEFLEIYNLEVVSIPTNLAIKRKDLNDLIYKSE
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEEECCCCEEECCCHHHHHHHCH
KEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII
HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGD
HHCCCCCEEEEEECCCCCCEEEEEHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCC
PGTSQFYLSLEDNLLRIFGSDRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFE
CCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SRKHLLEYDDVANEQRKSVYKFRDELLDINYDISAKIAENREYALNQIFSKLKAFDHQNL
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
SEEELLGLKNVLKEDFNAHVELEDLEKASPIEKFVAEKLKSDYENKMKVLDSEQRSRIER
CHHHHHHHHHHHHHHCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLEFIEDIKIEAIK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFSKIQFENEQDSSDAERYLDNFSEEREHESVTYRHEETLDEDLNVAMKAFSKTPKRNEP
HHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
CPCQSGKKYKDCCAKSGPKKGLFAK
CCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIKAIIGKIIGTRNDRWIKQYKKQVLTINALEPTYEKMSDVELQNAFEELKKRVRSTEKN
CHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQEKTLLEVLPESFAITREASKRILKMRHFDVQLIGGMVLNDGKIAEMKTGEGKTLVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEECCCCEEEEECCCCCHHHHHH
AVALNALKGESVYVVTVNDYLAHRDSKEMEPLYHFLGYSVGTITASVRDDDERLEIYSKD
HHHHHHHCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCHHHHEEEECCCCHHHHHEEECC
IVYGTNNEFGFDYLRDNMKYSLEHKVQKSHAFAIVDEVDSILIDEARTPLIISGPVDRRM
EEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHH
ENYNKADEVAKSMQVETDFTIDEKNRTILITEEGIKKAENLFGVDNLYKIENAALSHHLD
HHCCHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QALKANYLFFIDKDYIVANNEVVIVDEFTGRLSEGRRFSEGLHQALEAKEGVSIKEESQT
HHHHCCEEEEEECCEEEECCCEEEEECCCCCHHCCHHHHHHHHHHHHHHCCCCCCHHHHH
LADITFQNYFRMFSKLSGMTGTAQTEATEFLEIYNLEVVSIPTNLAIKRKDLNDLIYKSE
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCEEEEEECCCCEEECCCHHHHHHHCH
KEKFDAVILKIKELHDKGQPVLVGTASIEKSETLHALLKKERIPHTVLNAKQHTKEAEII
HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KDAGLKGAVTIATNMAGRGVDIKLTDEIKELGGLYIIGTERHESRRIDNQLRGRSGRQGD
HHCCCCCEEEEEECCCCCCEEEEEHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCC
PGTSQFYLSLEDNLLRIFGSDRIKGVMEKLGLKDGEHIESKLVTRAVENAQKKVENLHFE
CCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SRKHLLEYDDVANEQRKSVYKFRDELLDINYDISAKIAENREYALNQIFSKLKAFDHQNL
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
SEEELLGLKNVLKEDFNAHVELEDLEKASPIEKFVAEKLKSDYENKMKVLDSEQRSRIER
CHHHHHHHHHHHHHHCCCCEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IVYLQILDNAWREHLYTMDNLKTGINLRGYNQKDPLVEYKKESYNLFLEFIEDIKIEAIK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TFSKIQFENEQDSSDAERYLDNFSEEREHESVTYRHEETLDEDLNVAMKAFSKTPKRNEP
HHHHHEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
CPCQSGKKYKDCCAKSGPKKGLFAK
CCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA