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The map label for this gene is hslV [H]

Identifier: 108562914

GI number: 108562914

Start: 508000

End: 508542

Strand: Direct

Name: hslV [H]

Synonym: HPAG1_0489

Alternate gene names: 108562914

Gene position: 508000-508542 (Clockwise)

Preceding gene: 108562913

Following gene: 108562915

Centisome position: 31.82

GC content: 44.01

Gene sequence:

>543_bases
ATGTTTGAAGCGACGACGATTCTAGGCTATAGAGGGGAGATGGGGGGCAAGAAGTTCGCGCTCATTGGAGGCGATGGGCA
GGTAACTTTGGGTAATTGCGTGGTCAAAGCCAATGCGACAAAAATCAGGAGCTTGTATCACAACCAGGTTTTAAGCGGGT
TTGCCGGTAGCACTGCGGACGCTTTTAGTTTGTTTGATATGTTTGAACGCATATTAGAGAGCAAAAAGGGGGATTTGTTT
AAAAGCGTGGTGGATTTCAGCAAAGAATGGCGCAAAGACAAGTATTTACGCCGACTGGAAGCGATGATGATCGTTTTAAA
TTTGGATCACATTTTCATTTTGAGCGGCACGGGCGATGTTTTAGAGGCTGAAGACAATAAGATTGCTGCTATTGGGAGTG
GGGGGAATTACGCCTTAAGCGCGGCTAGGGCTTTAGATCATTTCGCTCATTTAGAGCCTAGAAAACTTGTAGAAGAGTCC
TTAAAAATCGCAGGGGATCTTTGCATTTACACCAACACAAATATTAAAATTTTGGAGCTTTAA

Upstream 100 bases:

>100_bases
CAAACACCCGATTAAAAGCACAGGGATTTATGAGATTGAAGTCAAGCTTGGATCGGGGGTTGTGGGCGCGTTTAAAATTG
ATGTGGTGGCTGAGTAGAAA

Downstream 100 bases:

>100_bases
TGTCTAAATTGAATATGACCCCAAGAGAAATTGTCGCTTATTTAGATGAATATATCATTGGGCAAAAGGAAGCTAAAAAG
TCTATCGCTATCGCTTTTAG

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MFEATTILGYRGEMGGKKFALIGGDGQVTLGNCVVKANATKIRSLYHNQVLSGFAGSTADAFSLFDMFERILESKKGDLF
KSVVDFSKEWRKDKYLRRLEAMMIVLNLDHIFILSGTGDVLEAEDNKIAAIGSGGNYALSAARALDHFAHLEPRKLVEES
LKIAGDLCIYTNTNIKILEL

Sequences:

>Translated_180_residues
MFEATTILGYRGEMGGKKFALIGGDGQVTLGNCVVKANATKIRSLYHNQVLSGFAGSTADAFSLFDMFERILESKKGDLF
KSVVDFSKEWRKDKYLRRLEAMMIVLNLDHIFILSGTGDVLEAEDNKIAAIGSGGNYALSAARALDHFAHLEPRKLVEES
LKIAGDLCIYTNTNIKILEL
>Mature_180_residues
MFEATTILGYRGEMGGKKFALIGGDGQVTLGNCVVKANATKIRSLYHNQVLSGFAGSTADAFSLFDMFERILESKKGDLF
KSVVDFSKEWRKDKYLRRLEAMMIVLNLDHIFILSGTGDVLEAEDNKIAAIGSGGNYALSAARALDHFAHLEPRKLVEES
LKIAGDLCIYTNTNIKILEL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=160, Percent_Identity=51.875, Blast_Score=167, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19826; Mature: 19826

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEATTILGYRGEMGGKKFALIGGDGQVTLGNCVVKANATKIRSLYHNQVLSGFAGSTAD
CCCCEEEEEECCCCCCCEEEEECCCCCEEECCEEEECCHHHHHHHHHHHHHHCCCCCCHH
AFSLFDMFERILESKKGDLFKSVVDFSKEWRKDKYLRRLEAMMIVLNLDHIFILSGTGDV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCE
LEAEDNKIAAIGSGGNYALSAARALDHFAHLEPRKLVEESLKIAGDLCIYTNTNIKILEL
EECCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCEEEEEC
>Mature Secondary Structure
MFEATTILGYRGEMGGKKFALIGGDGQVTLGNCVVKANATKIRSLYHNQVLSGFAGSTAD
CCCCEEEEEECCCCCCCEEEEECCCCCEEECCEEEECCHHHHHHHHHHHHHHCCCCCCHH
AFSLFDMFERILESKKGDLFKSVVDFSKEWRKDKYLRRLEAMMIVLNLDHIFILSGTGDV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCE
LEAEDNKIAAIGSGGNYALSAARALDHFAHLEPRKLVEESLKIAGDLCIYTNTNIKILEL
EECCCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA