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The map label for this gene is yqhT [H]

Identifier: 108562835

GI number: 108562835

Start: 420825

End: 421898

Strand: Direct

Name: yqhT [H]

Synonym: HPAG1_0410

Alternate gene names: 108562835

Gene position: 420825-421898 (Clockwise)

Preceding gene: 108562834

Following gene: 108562836

Centisome position: 26.36

GC content: 41.53

Gene sequence:

>1074_bases
ATGAAAGGATTAGAAAGAGAATCGCATTTCACGCTCAATGAGAACGCGATGTTTTTTGAGTGCACTTATAGTTGCGATAA
CGCTTTGTTTTTGCAATTAGACGATCGCTCGTTTTTTATCACTGATTCTCGCTACACTCAAGAAGCTAAAGAAAGCATTC
AGCCTAAAAATGGCGTTTTAGCGGAAGTGATAGAATCTAGCGATTTAGTGCAAAGCGCGATTGATTTGATTACAAAACAC
TCGGTTAAAAAGCTCTTTTTTGACCCCAATCAAGTGAATTTGCAAACCTATAAGCGTTTGGATTCGGCGATTGGGAATAA
GGTTATTTTAGAGGGCGTGCCTAGTTACCACCGCCAAAAACGCATCATTAAAAACGATCATGAGATCCAACTCCTCAAAA
AATCTCAAGCACTGAATGTTGAAGCTTTTGAAAATTTTGCCGAGTATGTGAAAAAGATTTTTGATGAAAAAGAATCCTTG
AGCGAGCGGTATTTGCAGCATAAGGTTAAGGACTTTTTGACTAAAGAGGGGGTTTATGATCTGAGTTTTGAGCCTATTTT
AGCCTTGAATGCGAACGCGAGCAAGCCCCATGCTTTGCCTAGCGCAAAGGATTTTTTAAAAGCGGAGCACAGCATTCTTT
TAGATATGGGGATCAAATACGAACGCTATTGCTCTGATAGGACTCGCACGGCTTTTTTTGACCCTAAAGATTTTGTCTTT
AAAAGAGAGCAGAGTTTCAAGGACAAAGAGCGTCAAAAGATTTATGACATTGTGAAAGAAGCGCAAGAAAAGGCTATTGC
AGGCATTAGAGCGGGCATGACCGGTAAAGAAGCGGACGGCTTGGCTAGGGGGGTGATTAGCGATTATGGTTACGGGCAGT
ATTTCACTCACAGCACCGGGCATGGCATTGGCTTAGACATCCATGAGCTTCCTTATATTTCATCGCGCAGTGAAACCATT
TTAGAAGAGGGCATGGTGTTTTCTGTAGAGCCTGGGATTTATATCCCTGGATTTTTTGGGGTGCGCATTGAAGATTTAGT
GGTGATCAAAAATTCTAGGGCTGAGCTTTTGTGA

Upstream 100 bases:

>100_bases
GCGATGGTCAATATTTTAGCCGAAATGAAAGCGTTCCAAGAAGCCCAAAAAAACAACCCTAATAACCCCATTAACAATCA
AAAATAAAAGGGGGCTACCC

Downstream 100 bases:

>100_bases
TGCGAGAGATCCTTACTAACCGCTTTTTCCCCAGCCTTTTTAAAAAAAGGCTTGATTTTTCTAACAGGGTGGTTTTAGGG
TTGGGATCTAATCTTAAAAA

Product: proline peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKGLERESHFTLNENAMFFECTYSCDNALFLQLDDRSFFITDSRYTQEAKESIQPKNGVLAEVIESSDLVQSAIDLITKH
SVKKLFFDPNQVNLQTYKRLDSAIGNKVILEGVPSYHRQKRIIKNDHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESL
SERYLQHKVKDFLTKEGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKEAQEKAIAGIRAGMTGKEADGLARGVISDYGYGQYFTHSTGHGIGLDIHELPYISSRSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL

Sequences:

>Translated_357_residues
MKGLERESHFTLNENAMFFECTYSCDNALFLQLDDRSFFITDSRYTQEAKESIQPKNGVLAEVIESSDLVQSAIDLITKH
SVKKLFFDPNQVNLQTYKRLDSAIGNKVILEGVPSYHRQKRIIKNDHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESL
SERYLQHKVKDFLTKEGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKEAQEKAIAGIRAGMTGKEADGLARGVISDYGYGQYFTHSTGHGIGLDIHELPYISSRSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL
>Mature_357_residues
MKGLERESHFTLNENAMFFECTYSCDNALFLQLDDRSFFITDSRYTQEAKESIQPKNGVLAEVIESSDLVQSAIDLITKH
SVKKLFFDPNQVNLQTYKRLDSAIGNKVILEGVPSYHRQKRIIKNDHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESL
SERYLQHKVKDFLTKEGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKEAQEKAIAGIRAGMTGKEADGLARGVISDYGYGQYFTHSTGHGIGLDIHELPYISSRSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=259, Percent_Identity=27.027027027027, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI11559925, Length=279, Percent_Identity=26.8817204301075, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI93141226, Length=250, Percent_Identity=28, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788728, Length=324, Percent_Identity=32.0987654320988, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789275, Length=277, Percent_Identity=24.9097472924188, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17509539, Length=237, Percent_Identity=29.535864978903, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320922, Length=271, Percent_Identity=23.9852398523985, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40845; Mature: 40845

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLERESHFTLNENAMFFECTYSCDNALFLQLDDRSFFITDSRYTQEAKESIQPKNGVL
CCCCCCCCCEEECCCEEEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCHH
AEVIESSDLVQSAIDLITKHSVKKLFFDPNQVNLQTYKRLDSAIGNKVILEGVPSYHRQK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHH
RIIKNDHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESLSERYLQHKVKDFLTKEGVYD
HHHCCCCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
LSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCHHHHH
KREQSFKDKERQKIYDIVKEAQEKAIAGIRAGMTGKEADGLARGVISDYGYGQYFTHSTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEECCCC
HGIGLDIHELPYISSRSETILEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL
CCCCCCHHHCCCCCCCHHHHHHCCCEEEECCCEEECCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKGLERESHFTLNENAMFFECTYSCDNALFLQLDDRSFFITDSRYTQEAKESIQPKNGVL
CCCCCCCCCEEECCCEEEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCHH
AEVIESSDLVQSAIDLITKHSVKKLFFDPNQVNLQTYKRLDSAIGNKVILEGVPSYHRQK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHH
RIIKNDHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESLSERYLQHKVKDFLTKEGVYD
HHHCCCCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
LSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEECCCHHHHH
KREQSFKDKERQKIYDIVKEAQEKAIAGIRAGMTGKEADGLARGVISDYGYGQYFTHSTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEECCCC
HGIGLDIHELPYISSRSETILEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRAELL
CCCCCCHHHCCCCCCCHHHHHHCCCEEEECCCEEECCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]