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The map label for this gene is yleA [C]

Identifier: 108562712

GI number: 108562712

Start: 291554

End: 292810

Strand: Direct

Name: yleA [C]

Synonym: HPAG1_0287

Alternate gene names: 108562712

Gene position: 291554-292810 (Clockwise)

Preceding gene: 108562711

Following gene: 108562713

Centisome position: 18.26

GC content: 39.3

Gene sequence:

>1257_bases
ATGAAAAAAGTCTATTTCAAAACTTTTGGGTGCAGGACGAATCTTTTTGACACGCAAGTGATGGGTGAGAATTTGAAGGA
CTTTAGCGCGACCTTAGAAGAACAAGAAGCCGATATTATTGTGATCAATTCTTGCACCGTGACTAATGGGGCCGATAGCG
CGGTAAGGAGTTACGCTAAAAAAATGGTGCGATTAAATAAAGAAGTGTTATTTACTGGCTGCGGGGTGAAAACTCAAGGC
AAAGAGCTTTTTGAAAAAGGGTTTTTAAAGGGCGTTTTTGGGCATGACAATAAAGAAAAGATTAACGCGCTTTTACAAGA
AAAAAAGCGTTTTTTTATAGATGACAATTTAGAAAACAAGCACTTAGACACCACGATGGTGAGCGAGTTTGTGGGAAAAA
CCAGGGCGTTTATCAAGATCCAAGAAGGCTGTGATTTTGATTGCAATTATTGCATTATCCCAAGCGTGAGAGGGAGGGCT
AGGAGTTTTGAAGAGAGGAAAATTTTAGAGCAAGTGGGCCTTTTATGCTCTAAAGGGGTTCAAGAAGTGGTTTTAACCGG
CACCAATGTGGGGAGCTATGGGAAGGATAGAGGAAGCAATATCGCGCGATTGATTAAAAAATTAAGTCAGATTGCTGGAT
TAAAACGCATAAGGATTGGGAGCTTAGAACCTAATCAAATCAACGATGAATTTTTAGAGCTTTTAGAAGAGGATTTTTTA
GAAAAACATTTGCATATCGCTTTGCAGCACAGCCATGATTTCATGCTAGAGAGGATGAATAGAAGAAACCGCACTAAAAG
CGATAGGGAATTATTAGAGGTAATCGCTTCTAAGAATTTTGCCATCGGCACGGATTTTATTGTAGGGCATCCGGGCGAGA
GCGAAAGCGTTTTTGAAAAGGCGTTTAAAAATTTAGAAAGCTTGCCCTTAACGCACATCCACCCTTTTATTTACAGCAAA
CGAAAAGACACCCCCTCTAGTTTGATGACTGATAGCGTGAGCTTGGAAGATTCTAAAAAGCGTTTGAATGCGATTAAGGA
TTTGATTTTACATAAAAATAAGGCGTTCAGGCAATTGCAACTCAAGCTCAACACGCCTCTAAAAGCTTTAGTGGAAACGC
AAAAAGACGGCGAATTTAAAGCCTTAGATCAATTCTTCAACCCCATTAAAATCAAAAGCGATAAGCCTTTAAGGGCCAGT
TTTTTAGAAATCAAAGAGTATGAAATTAAGGAGAGAGAAAACCATGCCGTTTTCTAA

Upstream 100 bases:

>100_bases
TGAAAGAAGAAAATATCCATATCGCTTATACGACCAGCAAGTTGCTTAAAGTGGATGCTGATTTTTTAGGCGATGGTTTT
GGGAATAAAAGGGAACAAAA

Downstream 100 bases:

>100_bases
AAATTTAGAAAACCTCACCGCTCCCTTCAAACGCATTAAAAACCGCTCGCTTGTTTTGGCGTTAGGGTTTTTGATCCTTA
CTTTTTGCTTGCTTCTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIVINSCTVTNGADSAVRSYAKKMVRLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCSKGVQEVVLTGTNVGSYGKDRGSNIARLIKKLSQIAGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLERMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEKAFKNLESLPLTHIHPFIYSK
RKDTPSSLMTDSVSLEDSKKRLNAIKDLILHKNKAFRQLQLKLNTPLKALVETQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIKEYEIKERENHAVF

Sequences:

>Translated_418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIVINSCTVTNGADSAVRSYAKKMVRLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCSKGVQEVVLTGTNVGSYGKDRGSNIARLIKKLSQIAGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLERMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEKAFKNLESLPLTHIHPFIYSK
RKDTPSSLMTDSVSLEDSKKRLNAIKDLILHKNKAFRQLQLKLNTPLKALVETQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIKEYEIKERENHAVF
>Mature_418_residues
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIVINSCTVTNGADSAVRSYAKKMVRLNKEVLFTGCGVKTQG
KELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENKHLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRA
RSFEERKILEQVGLLCSKGVQEVVLTGTNVGSYGKDRGSNIARLIKKLSQIAGLKRIRIGSLEPNQINDEFLELLEEDFL
EKHLHIALQHSHDFMLERMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEKAFKNLESLPLTHIHPFIYSK
RKDTPSSLMTDSVSLEDSKKRLNAIKDLILHKNKAFRQLQLKLNTPLKALVETQKDGEFKALDQFFNPIKIKSDKPLRAS
FLEIKEYEIKERENHAVF

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=433, Percent_Identity=26.7898383371824, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI28872782, Length=369, Percent_Identity=26.8292682926829, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI28872784, Length=369, Percent_Identity=26.8292682926829, Blast_Score=122, Evalue=7e-28,
Organism=Escherichia coli, GI1786882, Length=394, Percent_Identity=28.4263959390863, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787057, Length=366, Percent_Identity=24.8633879781421, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17553146, Length=410, Percent_Identity=26.3414634146341, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71996771, Length=218, Percent_Identity=26.1467889908257, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356207, Length=388, Percent_Identity=28.3505154639175, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI19922432, Length=365, Percent_Identity=26.5753424657534, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47849; Mature: 47849

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS01305 MOAA_NIFB_PQQE ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIVINSCTVTNGADSAVRSYAK
CCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHCCCCEEEEECEECCCCCHHHHHHHHH
KMVRLNKEVLFTGCGVKTQGKELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENK
HHHHHCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCCCC
HLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRARSFEERKILEQVGLLCSKGV
CCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCH
QEVVLTGTNVGSYGKDRGSNIARLIKKLSQIAGLKRIRIGSLEPNQINDEFLELLEEDFL
HHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCCCHHHHHHHHHHHH
EKHLHIALQHSHDFMLERMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCEEEECCCCCHHHHHH
AFKNLESLPLTHIHPFIYSKRKDTPSSLMTDSVSLEDSKKRLNAIKDLILHKNKAFRQLQ
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LKLNTPLKALVETQKDGEFKALDQFFNPIKIKSDKPLRASFLEIKEYEIKERENHAVF
HHHCCCHHHHHHCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKVYFKTFGCRTNLFDTQVMGENLKDFSATLEEQEADIIVINSCTVTNGADSAVRSYAK
CCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHHCCCCEEEEECEECCCCCHHHHHHHHH
KMVRLNKEVLFTGCGVKTQGKELFEKGFLKGVFGHDNKEKINALLQEKKRFFIDDNLENK
HHHHHCHHHEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCCCC
HLDTTMVSEFVGKTRAFIKIQEGCDFDCNYCIIPSVRGRARSFEERKILEQVGLLCSKGV
CCHHHHHHHHHCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCH
QEVVLTGTNVGSYGKDRGSNIARLIKKLSQIAGLKRIRIGSLEPNQINDEFLELLEEDFL
HHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCCCHHHHHHHHHHHH
EKHLHIALQHSHDFMLERMNRRNRTKSDRELLEVIASKNFAIGTDFIVGHPGESESVFEK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEECCCEEEECCCCCHHHHHH
AFKNLESLPLTHIHPFIYSKRKDTPSSLMTDSVSLEDSKKRLNAIKDLILHKNKAFRQLQ
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
LKLNTPLKALVETQKDGEFKALDQFFNPIKIKSDKPLRASFLEIKEYEIKERENHAVF
HHHCCCHHHHHHCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]