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The map label for this gene is aprE [H]

Identifier: 103488236

GI number: 103488236

Start: 2908033

End: 2909298

Strand: Reverse

Name: aprE [H]

Synonym: Sala_2759

Alternate gene names: 103488236

Gene position: 2909298-2908033 (Counterclockwise)

Preceding gene: 103488237

Following gene: 103488234

Centisome position: 86.97

GC content: 65.88

Gene sequence:

>1266_bases
ATGATCAGGCGAATCGTCACATTCTGGCAGCGCCTGCGCGGAAGCGAACAGATCATGGTGGCGGCCGCCGTCGGCCTGGT
GCTGTTTCTGTTGTGGGCGAGCATCGCGCGCGTCGACGAAATATCGCGCGGGCAGGGCCGCGTCATCCCCTCTTCACGGG
TGCAGATCATCCAGTCGGCCGAACCGTCGACGATCCGTGAAATCCTCGTCCGGTCGGGCCAGACGGTGGAGAAGGGGCAA
TTGCTCGTGCGGCTCGACAATACGACGTCGCAGTCCGAACTGGGGCAGCTCGAAACCGAGAACGAACGCCTTGCGCAGCG
CGCAGCGCGCCTCGCGGGCGAGGGGGGAAGCGGTGCGGGCTGCACGGGCGACAGTTGCGGCGACGAAGCGCGGCTGGCCG
AAGTGCGGCGTTCGGCGCTGCAAAGCCAGCTCGCCGCGCTCTCGGCCAGCGTCGAACAACGCCGCCGCGACCTGGGCGAA
GCGCAGGCGACGGCAAGCGCGCTCGAAAGCAGCCTGCGGCTCGCGCGCGAACAGGTGGCGATGCTCGAACCGCTCGCGGC
GCGCGGCGTCGTGCCGCAGACCGAACTGCTCACCGCACAGCGCGAGGTCGTCGATATTCAGGGCCGCCTCGCCGCCGCGC
GCCAGGCGATGTCGCGCTCGCAGGCGGCGATCCGCGAAGCGAGTGCCGAGGTATCGCGCGCGCGGTTCGACTTCCAGCAG
GAAGCGCTCAACGAACGCAGCCAGCTCACCACCAAGATGGCGGTCAACGAAGAAACGATCCGCGGCGCCGAGGGGCGGCT
GGCGCGCTCGGAGATCCGCTCGCCGGCGCGCGGCGTCGTCAACGATCTGCTCGTCAACACGCTGGGCGGCTTCGTCAATG
CCGGCGAACAGATCATGCAGATCGTGCCGCTCGGCGACAAATTGCTCATCGAAACGCGCGTCACGCCGCGCGACATCGCC
TTCATCAAGGTCGGCGACCCGGCGAACGTCAAGGTCACCGCCTATGATTTTTCGATCTATGGCGGGCTGAAGGGCAAGGT
CGTGCGCGTGTCGCCCGACAGCATCTATGACGAGGTGGAGCGCGAAGCCTATTTCACCGTCGTCGTCGAAACGACGAACA
GCTTTCTCGTATCGAACGGCCGACGCCTGCCGATCACTCCTGGGATGCTATGCGATGTCGAAATCCTGACGGGCAAGAAA
TCGGTGCTCAGCTATTTGCTCAAACCCGTTTTGAAGGTCAGCGGGACGGCCTTGACCGAACGCTGA

Upstream 100 bases:

>100_bases
GGGTACCGAGCATCCCCGATCCGACCAGCAGCACGTCGCGCTTCGACAGCCTGACGAGCCGACAAGGCGCGACGCCCGCG
ACCGATGGTGTGCCCGGACA

Downstream 100 bases:

>100_bases
TCGGCGAGCGCAAGGGTGATGCTCTTGCGCGCCCCCGGAACGATGGTTGCAGCCGGGGTTTCCGCCGCGGTGCGATAGGC
GTGGACCCACCGCCGGTCGG

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MIRRIVTFWQRLRGSEQIMVAAAVGLVLFLLWASIARVDEISRGQGRVIPSSRVQIIQSAEPSTIREILVRSGQTVEKGQ
LLVRLDNTTSQSELGQLETENERLAQRAARLAGEGGSGAGCTGDSCGDEARLAEVRRSALQSQLAALSASVEQRRRDLGE
AQATASALESSLRLAREQVAMLEPLAARGVVPQTELLTAQREVVDIQGRLAAARQAMSRSQAAIREASAEVSRARFDFQQ
EALNERSQLTTKMAVNEETIRGAEGRLARSEIRSPARGVVNDLLVNTLGGFVNAGEQIMQIVPLGDKLLIETRVTPRDIA
FIKVGDPANVKVTAYDFSIYGGLKGKVVRVSPDSIYDEVEREAYFTVVVETTNSFLVSNGRRLPITPGMLCDVEILTGKK
SVLSYLLKPVLKVSGTALTER

Sequences:

>Translated_421_residues
MIRRIVTFWQRLRGSEQIMVAAAVGLVLFLLWASIARVDEISRGQGRVIPSSRVQIIQSAEPSTIREILVRSGQTVEKGQ
LLVRLDNTTSQSELGQLETENERLAQRAARLAGEGGSGAGCTGDSCGDEARLAEVRRSALQSQLAALSASVEQRRRDLGE
AQATASALESSLRLAREQVAMLEPLAARGVVPQTELLTAQREVVDIQGRLAAARQAMSRSQAAIREASAEVSRARFDFQQ
EALNERSQLTTKMAVNEETIRGAEGRLARSEIRSPARGVVNDLLVNTLGGFVNAGEQIMQIVPLGDKLLIETRVTPRDIA
FIKVGDPANVKVTAYDFSIYGGLKGKVVRVSPDSIYDEVEREAYFTVVVETTNSFLVSNGRRLPITPGMLCDVEILTGKK
SVLSYLLKPVLKVSGTALTER
>Mature_421_residues
MIRRIVTFWQRLRGSEQIMVAAAVGLVLFLLWASIARVDEISRGQGRVIPSSRVQIIQSAEPSTIREILVRSGQTVEKGQ
LLVRLDNTTSQSELGQLETENERLAQRAARLAGEGGSGAGCTGDSCGDEARLAEVRRSALQSQLAALSASVEQRRRDLGE
AQATASALESSLRLAREQVAMLEPLAARGVVPQTELLTAQREVVDIQGRLAAARQAMSRSQAAIREASAEVSRARFDFQQ
EALNERSQLTTKMAVNEETIRGAEGRLARSEIRSPARGVVNDLLVNTLGGFVNAGEQIMQIVPLGDKLLIETRVTPRDIA
FIKVGDPANVKVTAYDFSIYGGLKGKVVRVSPDSIYDEVEREAYFTVVVETTNSFLVSNGRRLPITPGMLCDVEILTGKK
SVLSYLLKPVLKVSGTALTER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 45783; Mature: 45783

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRIVTFWQRLRGSEQIMVAAAVGLVLFLLWASIARVDEISRGQGRVIPSSRVQIIQSA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
EPSTIREILVRSGQTVEKGQLLVRLDNTTSQSELGQLETENERLAQRAARLAGEGGSGAG
CHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
CTGDSCGDEARLAEVRRSALQSQLAALSASVEQRRRDLGEAQATASALESSLRLAREQVA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLEPLAARGVVPQTELLTAQREVVDIQGRLAAARQAMSRSQAAIREASAEVSRARFDFQQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALNERSQLTTKMAVNEETIRGAEGRLARSEIRSPARGVVNDLLVNTLGGFVNAGEQIMQ
HHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHH
IVPLGDKLLIETRVTPRDIAFIKVGDPANVKVTAYDFSIYGGLKGKVVRVSPDSIYDEVE
HHCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCEEEECCHHHHHHHH
REAYFTVVVETTNSFLVSNGRRLPITPGMLCDVEILTGKKSVLSYLLKPVLKVSGTALTE
CCEEEEEEEECCCCHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCHHCC
R
C
>Mature Secondary Structure
MIRRIVTFWQRLRGSEQIMVAAAVGLVLFLLWASIARVDEISRGQGRVIPSSRVQIIQSA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
EPSTIREILVRSGQTVEKGQLLVRLDNTTSQSELGQLETENERLAQRAARLAGEGGSGAG
CHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
CTGDSCGDEARLAEVRRSALQSQLAALSASVEQRRRDLGEAQATASALESSLRLAREQVA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLEPLAARGVVPQTELLTAQREVVDIQGRLAAARQAMSRSQAAIREASAEVSRARFDFQQ
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALNERSQLTTKMAVNEETIRGAEGRLARSEIRSPARGVVNDLLVNTLGGFVNAGEQIMQ
HHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHH
IVPLGDKLLIETRVTPRDIAFIKVGDPANVKVTAYDFSIYGGLKGKVVRVSPDSIYDEVE
HHCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCEEEECCHHHHHHHH
REAYFTVVVETTNSFLVSNGRRLPITPGMLCDVEILTGKKSVLSYLLKPVLKVSGTALTE
CCEEEEEEEECCCCHHHCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]