Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 103488195

GI number: 103488195

Start: 2866731

End: 2867756

Strand: Reverse

Name: asd [H]

Synonym: Sala_2718

Alternate gene names: 103488195

Gene position: 2867756-2866731 (Counterclockwise)

Preceding gene: 103488196

Following gene: 103488194

Centisome position: 85.73

GC content: 63.65

Gene sequence:

>1026_bases
ATGGGTTACCGGATCGTCGTCGCGGGTGCGACGGGCAATGTCGGACGCGAAGTCCTCGCCATCCTCGCCGAGCGCGAATT
TCCCTATGACGAGCTGGCGGCGGTCGCGTCGCCGCGCAGCCAGGGCGACACGATCGAGATCGGCGACAGCGGCAAGACCG
TGAAATGCCAGAACATCGAGAACTTCGACTGGGCGGGCTGGGACATGGCGATCTTTGCGATCGGCAGCGACGCGACCGCG
ATCCATGCGCCCAAGGCCGCGGCGGCGGGCTGCATCGTGATCGACAACAGCTCGCTCTATCGCATGGACCCCGACGTGCC
GCTGATCGTGCCCGAGGTGAACCCCGATGCGATCGACGGCTATACCAGGCGCAACATCATCGCGAACCCCAATTGCTCGA
CCGCGCAGATGGTCGTCGCGCTGAAGCCGCTCCATGACGCCGCGACGATCAGGCGCGTCGTCGTCTCGACCTATCAGTCG
GTCAGCGGCGCGGGCAAGGCGGGCATGGACGAGCTGTGGAACCAGACGCGCCAGATTTTCGTCGGCGACGAAAAGGATGT
GCAGAAGTTCACCAAGCAGATCGCCTTCAACGTCATCCCGCACATCGACAAGTTCCTCGACGACGGCTCGACCAAGGAAG
AGTGGAAGATGGTCGTCGAAACCAAGAAGATTCTCGATCCCAGGATCAAGGTCACCGCGACCTGCGTCCGCGTCCCCGTG
TTCGTGGGCCATTCGGAAGCGATCAATATCGAGACCGAAAAGGAATTGTCGGCCGAGGACGCGCAGCGCATCCTGCGCGA
AGCGCCCGGCGTCGTGCTCCACGACAAGCGCGAGGACGGCGGCTACACCACGCCCGTCGAATGCGTCGGCGATTTCGCGA
CCTTCGTCAGCCGCGTGCGCGAGGATCCGACCGTCGAAAACGGTCTCAACCTCTGGTGCGTTTCGGACAATCTTCGCAAG
GGCGCGGCGCTCAACGCGGTGCAGATCGCCGAGCTGCTCGGGCGGCGACATCTGAAGAAGGGGTAA

Upstream 100 bases:

>100_bases
TCTCTCATCCAAAGCCGAAACAGCTTTCCAGAACGACCGGTTCGGCCAAGGGGCGGAACCGGTCGTTTTTCGTTTCACGG
ACATCATAAAGGACAATTTC

Downstream 100 bases:

>100_bases
TTTCCTCCCGTTCTCCGCTCGTGTCGAGCGAAGTCGAGACACCCGGAAGGCAAGCGTCGCGCCGATGGGCATCTCGACTT
CGCTCGATGCGAGCGGGTAG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGYRIVVAGATGNVGREVLAILAEREFPYDELAAVASPRSQGDTIEIGDSGKTVKCQNIENFDWAGWDMAIFAIGSDATA
IHAPKAAAAGCIVIDNSSLYRMDPDVPLIVPEVNPDAIDGYTRRNIIANPNCSTAQMVVALKPLHDAATIRRVVVSTYQS
VSGAGKAGMDELWNQTRQIFVGDEKDVQKFTKQIAFNVIPHIDKFLDDGSTKEEWKMVVETKKILDPRIKVTATCVRVPV
FVGHSEAINIETEKELSAEDAQRILREAPGVVLHDKREDGGYTTPVECVGDFATFVSRVREDPTVENGLNLWCVSDNLRK
GAALNAVQIAELLGRRHLKKG

Sequences:

>Translated_341_residues
MGYRIVVAGATGNVGREVLAILAEREFPYDELAAVASPRSQGDTIEIGDSGKTVKCQNIENFDWAGWDMAIFAIGSDATA
IHAPKAAAAGCIVIDNSSLYRMDPDVPLIVPEVNPDAIDGYTRRNIIANPNCSTAQMVVALKPLHDAATIRRVVVSTYQS
VSGAGKAGMDELWNQTRQIFVGDEKDVQKFTKQIAFNVIPHIDKFLDDGSTKEEWKMVVETKKILDPRIKVTATCVRVPV
FVGHSEAINIETEKELSAEDAQRILREAPGVVLHDKREDGGYTTPVECVGDFATFVSRVREDPTVENGLNLWCVSDNLRK
GAALNAVQIAELLGRRHLKKG
>Mature_340_residues
GYRIVVAGATGNVGREVLAILAEREFPYDELAAVASPRSQGDTIEIGDSGKTVKCQNIENFDWAGWDMAIFAIGSDATAI
HAPKAAAAGCIVIDNSSLYRMDPDVPLIVPEVNPDAIDGYTRRNIIANPNCSTAQMVVALKPLHDAATIRRVVVSTYQSV
SGAGKAGMDELWNQTRQIFVGDEKDVQKFTKQIAFNVIPHIDKFLDDGSTKEEWKMVVETKKILDPRIKVTATCVRVPVF
VGHSEAINIETEKELSAEDAQRILREAPGVVLHDKREDGGYTTPVECVGDFATFVSRVREDPTVENGLNLWCVSDNLRKG
AALNAVQIAELLGRRHLKKG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=342, Percent_Identity=39.4736842105263, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1789841, Length=351, Percent_Identity=29.6296296296296, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=401, Percent_Identity=29.1770573566085, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37259; Mature: 37128

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRIVVAGATGNVGREVLAILAEREFPYDELAAVASPRSQGDTIEIGDSGKTVKCQNIE
CCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEECCCCCEEEECCCC
NFDWAGWDMAIFAIGSDATAIHAPKAAAAGCIVIDNSSLYRMDPDVPLIVPEVNPDAIDG
CCCCCCCEEEEEEECCCCCEEECCCHHHCEEEEEECCCEEEECCCCCEEEECCCCCCCCC
YTRRNIIANPNCSTAQMVVALKPLHDAATIRRVVVSTYQSVSGAGKAGMDELWNQTRQIF
CHHCCEEECCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEE
VGDEKDVQKFTKQIAFNVIPHIDKFLDDGSTKEEWKMVVETKKILDPRIKVTATCVRVPV
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
FVGHSEAINIETEKELSAEDAQRILREAPGVVLHDKREDGGYTTPVECVGDFATFVSRVR
EECCCCEEECCCHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EDPTVENGLNLWCVSDNLRKGAALNAVQIAELLGRRHLKKG
CCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GYRIVVAGATGNVGREVLAILAEREFPYDELAAVASPRSQGDTIEIGDSGKTVKCQNIE
CEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEECCCCCEEEECCCC
NFDWAGWDMAIFAIGSDATAIHAPKAAAAGCIVIDNSSLYRMDPDVPLIVPEVNPDAIDG
CCCCCCCEEEEEEECCCCCEEECCCHHHCEEEEEECCCEEEECCCCCEEEECCCCCCCCC
YTRRNIIANPNCSTAQMVVALKPLHDAATIRRVVVSTYQSVSGAGKAGMDELWNQTRQIF
CHHCCEEECCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEE
VGDEKDVQKFTKQIAFNVIPHIDKFLDDGSTKEEWKMVVETKKILDPRIKVTATCVRVPV
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
FVGHSEAINIETEKELSAEDAQRILREAPGVVLHDKREDGGYTTPVECVGDFATFVSRVR
EECCCCEEECCCHHHCCHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
EDPTVENGLNLWCVSDNLRKGAALNAVQIAELLGRRHLKKG
CCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]