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The map label for this gene is yesM [H]

Identifier: 103488151

GI number: 103488151

Start: 2820151

End: 2821275

Strand: Reverse

Name: yesM [H]

Synonym: Sala_2674

Alternate gene names: 103488151

Gene position: 2821275-2820151 (Counterclockwise)

Preceding gene: 103488152

Following gene: 103488150

Centisome position: 84.34

GC content: 63.11

Gene sequence:

>1125_bases
ATGCCATTGTTCCGACTGACCTCGCCCGGTCCCTTTTTCGACAACAAGGTTCGCGCCTTCTGGAACCTCCAGATCCTCGG
CTGGGCGGCGTGGCTCGGGTTGCGCGGCGTGTCAGGGCTCGCCAACGGACAGGCGTTCACCTTCCTCATCCCGCAGGTGA
TTTCGGCGATCACGGGCTTTTCGCTGACGCTGATCCTGTCGGTCTGTTACCGCGCGCTCATCAATCGTCGGCCGCTGCTG
ATGTGGGGGGTCAGCTTTGGCCTCGCCGGCCTCGCGACCGCGCTGTGGGCGTTCATCGACGCCTGGGTCGCGCAGATCCA
GAACCCGGCGAGTGAAGCCGGATTTACGAGCCTTTTGCTCGGCGCGGTCTATATCGACGCGACCTCGCTCGCGGCCTGGT
CGGCGCTCTATTTCGCGATCAACTATTTCCTCCAGCTCGAGGAACAGAATGACCGCGTGCTGCGGCTCGAGGCGCAGGCG
GCGTCGGCGCAGCTCGCGATGCTGCGCTACCAGCTCAACCCGCATTTCCTGTTCAACACGCTGAACAGCATTTCGACGCT
CGTGCTCCTGAAACAGGCGGAGCCCGCGAATGCAATGTTGTCGCGCCTGTCGGCCTTCCTTCGCTACACGCTTGCCAACG
AGCCGACCGCACAGGTGACGCTGGCGCAGGAGATCGAGACGCTGAAGCTTTATCTCGATATCGAAAAAATGCGCTTCGAG
GACCGGCTGCGGCCGCATTTTGCGATCGACCCCGCGGTCGCGCGCGCGCGCCTGCCTTCGCTGCTGCTTCAGCCGCTCAT
CGAAAATGCGATCAAATATGCGGTGACGCCGCAGGAGGATGGCGCCGACATCACCATTTCCGCACAGCTGGCCGGTCAAA
ATGTCCGGATCACCGTGTCCGACACCGGCGCGGGATTGTCAGGTGACCGCACCGACCCCACCACGGGCGTTGCAACGGAA
TCGACCGGCGTGGGTTTAGCCAATATCCGGGACCGCCTGGCGCAGGCTTTTGGCGACCAGCACCGGTTCGACGCCCAGGC
GGGCGCTGAGGGCGGCTTCACGGTGGTGATCGAGTTTCCGTTCCAGCCCGATGGGCAAGCAAGAATTGGAACCGAAGACA
CATGA

Upstream 100 bases:

>100_bases
CGCGCCGACGGGCCGGCGCCGGTCGCGGCCGGATGACCCACGGCAGCGCCGCCCGCCTTGCCGCGCGCGGTCGTTGACCC
ACGCTCTCGCCCGCACTTCC

Downstream 100 bases:

>100_bases
CGATCAGAACCATTCTGGTGGATGACGAAAAACTGGCGACCCAGGGCCTGCAACTGCGGCTTGAGGCGCACCCGGATGTC
GAGGTGGTCGACACCGCCCA

Product: signal transduction histidine kinase, LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MPLFRLTSPGPFFDNKVRAFWNLQILGWAAWLGLRGVSGLANGQAFTFLIPQVISAITGFSLTLILSVCYRALINRRPLL
MWGVSFGLAGLATALWAFIDAWVAQIQNPASEAGFTSLLLGAVYIDATSLAAWSALYFAINYFLQLEEQNDRVLRLEAQA
ASAQLAMLRYQLNPHFLFNTLNSISTLVLLKQAEPANAMLSRLSAFLRYTLANEPTAQVTLAQEIETLKLYLDIEKMRFE
DRLRPHFAIDPAVARARLPSLLLQPLIENAIKYAVTPQEDGADITISAQLAGQNVRITVSDTGAGLSGDRTDPTTGVATE
STGVGLANIRDRLAQAFGDQHRFDAQAGAEGGFTVVIEFPFQPDGQARIGTEDT

Sequences:

>Translated_374_residues
MPLFRLTSPGPFFDNKVRAFWNLQILGWAAWLGLRGVSGLANGQAFTFLIPQVISAITGFSLTLILSVCYRALINRRPLL
MWGVSFGLAGLATALWAFIDAWVAQIQNPASEAGFTSLLLGAVYIDATSLAAWSALYFAINYFLQLEEQNDRVLRLEAQA
ASAQLAMLRYQLNPHFLFNTLNSISTLVLLKQAEPANAMLSRLSAFLRYTLANEPTAQVTLAQEIETLKLYLDIEKMRFE
DRLRPHFAIDPAVARARLPSLLLQPLIENAIKYAVTPQEDGADITISAQLAGQNVRITVSDTGAGLSGDRTDPTTGVATE
STGVGLANIRDRLAQAFGDQHRFDAQAGAEGGFTVVIEFPFQPDGQARIGTEDT
>Mature_373_residues
PLFRLTSPGPFFDNKVRAFWNLQILGWAAWLGLRGVSGLANGQAFTFLIPQVISAITGFSLTLILSVCYRALINRRPLLM
WGVSFGLAGLATALWAFIDAWVAQIQNPASEAGFTSLLLGAVYIDATSLAAWSALYFAINYFLQLEEQNDRVLRLEAQAA
SAQLAMLRYQLNPHFLFNTLNSISTLVLLKQAEPANAMLSRLSAFLRYTLANEPTAQVTLAQEIETLKLYLDIEKMRFED
RLRPHFAIDPAVARARLPSLLLQPLIENAIKYAVTPQEDGADITISAQLAGQNVRITVSDTGAGLSGDRTDPTTGVATES
TGVGLANIRDRLAQAFGDQHRFDAQAGAEGGFTVVIEFPFQPDGQARIGTEDT

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=249, Percent_Identity=30.5220883534137, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788446, Length=215, Percent_Identity=35.8139534883721, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40852; Mature: 40721

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFRLTSPGPFFDNKVRAFWNLQILGWAAWLGLRGVSGLANGQAFTFLIPQVISAITGF
CCCEECCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCH
SLTLILSVCYRALINRRPLLMWGVSFGLAGLATALWAFIDAWVAQIQNPASEAGFTSLLL
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GAVYIDATSLAAWSALYFAINYFLQLEEQNDRVLRLEAQAASAQLAMLRYQLNPHFLFNT
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHH
LNSISTLVLLKQAEPANAMLSRLSAFLRYTLANEPTAQVTLAQEIETLKLYLDIEKMRFE
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHEEEHEEEEHHHHHHH
DRLRPHFAIDPAVARARLPSLLLQPLIENAIKYAVTPQEDGADITISAQLAGQNVRITVS
HHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCEEEEEEE
DTGAGLSGDRTDPTTGVATESTGVGLANIRDRLAQAFGDQHRFDAQAGAEGGFTVVIEFP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
FQPDGQARIGTEDT
CCCCCCCCCCCCCC
>Mature Secondary Structure 
PLFRLTSPGPFFDNKVRAFWNLQILGWAAWLGLRGVSGLANGQAFTFLIPQVISAITGF
CCEECCCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCH
SLTLILSVCYRALINRRPLLMWGVSFGLAGLATALWAFIDAWVAQIQNPASEAGFTSLLL
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GAVYIDATSLAAWSALYFAINYFLQLEEQNDRVLRLEAQAASAQLAMLRYQLNPHFLFNT
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECHHHHHHHHHHHHCCCCHHHHHH
LNSISTLVLLKQAEPANAMLSRLSAFLRYTLANEPTAQVTLAQEIETLKLYLDIEKMRFE
HHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHEEEHEEEEHHHHHHH
DRLRPHFAIDPAVARARLPSLLLQPLIENAIKYAVTPQEDGADITISAQLAGQNVRITVS
HHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCEEEEEEE
DTGAGLSGDRTDPTTGVATESTGVGLANIRDRLAQAFGDQHRFDAQAGAEGGFTVVIEFP
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
FQPDGQARIGTEDT
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]