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The map label for this gene is uppP

Identifier: 103487618

GI number: 103487618

Start: 2240558

End: 2241358

Strand: Direct

Name: uppP

Synonym: Sala_2137

Alternate gene names: 103487618

Gene position: 2240558-2241358 (Clockwise)

Preceding gene: 103487617

Following gene: 103487619

Centisome position: 66.98

GC content: 64.79

Gene sequence:

>801_bases
ATGCACGACCTTGCCACCATCATCCTGCTCGGCATCATCGAGGGGCTGACCGAGTTCCTTCCCGTCTCCTCGACGGGGCA
TTTGATTCTGGCGAGCGAAATGCTGGGGTTCACCGGCGAAGGGTCGGCCGCGTTCAAGATCGCGATCCAGCTCGGCGCGA
TCCTGGCGGTGCTCGTCGCCTATCGTGCGCGTTTCTGGGGGGTCGGCATGGGGCTGCTGCGCGCCGATCCGGCGGCGGTT
GCGTTCACGCGCAACATACTGATTGGCTTCCTGCCGGCGATGCTCGTCGGCGCGGTCGCCTATGAAGGAGTTCGCGCGCT
GCTCGAATCGCCCGCGACCGTCGCGGTCGCGCTGCTGGTCGGCGGCATCGCGATTCTGGCGATCGAGCGCATGGTCAAGG
TGGTGAAGGTCGAAAGCGTCGAGGCGATGCCGCTGCGCACCGCGATCGCCATTGGCGCGGTCCAGTGCATCGCGATGATC
CCCGGCGTCAGCCGGTCGGGCGCGACGATCATGGGCGCGCTGCTGATGGGGGTCGAACGCAGGACGGCGGCCGAGTTCAG
CTTTTTCCTCGCGGTGCCGACGATGATGGGTGCAACCGCCTATTCATTGTGGAAGGACCGCGCGATCCTGACCTTCGACG
ATATGAACGCGATTGCGATCGGGCTGTTCGTTGCCTTTCTCGTCGCGCTGGTCGTGGTCAAGGCCTTCGTGGCAATCGTC
GGCCGCTTTGGTTTTGCGCCCTTCGCCTGGTATCGGATCATCGTCGGCGGCGGCGCGCTGTTATGGCTCGCATGGAAATA
G

Upstream 100 bases:

>100_bases
TATCGCCGCCACGGCCGGTTCACGGTCGAAACCCCCGCCTGACACCATCCCGGCCCCGGTGGTCGCGTGGTGATTGCCGG
GGCGCAGCCCAGGACATTTC

Downstream 100 bases:

>100_bases
GTCCGAAACGATACTAATTTGCGAAACATTATTACATCGGTCCGTTGAAACGAAAATCCGTGTCAGTTTTAGGTTAGCAA
TGCTGACCTAACTTGCATTT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MHDLATIILLGIIEGLTEFLPVSSTGHLILASEMLGFTGEGSAAFKIAIQLGAILAVLVAYRARFWGVGMGLLRADPAAV
AFTRNILIGFLPAMLVGAVAYEGVRALLESPATVAVALLVGGIAILAIERMVKVVKVESVEAMPLRTAIAIGAVQCIAMI
PGVSRSGATIMGALLMGVERRTAAEFSFFLAVPTMMGATAYSLWKDRAILTFDDMNAIAIGLFVAFLVALVVVKAFVAIV
GRFGFAPFAWYRIIVGGGALLWLAWK

Sequences:

>Translated_266_residues
MHDLATIILLGIIEGLTEFLPVSSTGHLILASEMLGFTGEGSAAFKIAIQLGAILAVLVAYRARFWGVGMGLLRADPAAV
AFTRNILIGFLPAMLVGAVAYEGVRALLESPATVAVALLVGGIAILAIERMVKVVKVESVEAMPLRTAIAIGAVQCIAMI
PGVSRSGATIMGALLMGVERRTAAEFSFFLAVPTMMGATAYSLWKDRAILTFDDMNAIAIGLFVAFLVALVVVKAFVAIV
GRFGFAPFAWYRIIVGGGALLWLAWK
>Mature_266_residues
MHDLATIILLGIIEGLTEFLPVSSTGHLILASEMLGFTGEGSAAFKIAIQLGAILAVLVAYRARFWGVGMGLLRADPAAV
AFTRNILIGFLPAMLVGAVAYEGVRALLESPATVAVALLVGGIAILAIERMVKVVKVESVEAMPLRTAIAIGAVQCIAMI
PGVSRSGATIMGALLMGVERRTAAEFSFFLAVPTMMGATAYSLWKDRAILTFDDMNAIAIGLFVAFLVALVVVKAFVAIV
GRFGFAPFAWYRIIVGGGALLWLAWK

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=262, Percent_Identity=44.6564885496183, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_SPHAL (Q1GR76)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617179.1
- GeneID:   4080134
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2137
- NMPDR:   fig|317655.9.peg.2063
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- ProtClustDB:   PRK00281
- BioCyc:   SALA317655:SALA_2137-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28014; Mature: 28014

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11b57db4)-; HASH(0x13d520f4)-; HASH(0x13d51fbc)-; HASH(0x13d72a48)-; HASH(0x13d72a6c)-; HASH(0x13d72a3c)-; HASH(0x13d4a30c)-; HASH(0x13d75874)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDLATIILLGIIEGLTEFLPVSSTGHLILASEMLGFTGEGSAAFKIAIQLGAILAVLVA
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YRARFWGVGMGLLRADPAAVAFTRNILIGFLPAMLVGAVAYEGVRALLESPATVAVALLV
HHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GGIAILAIERMVKVVKVESVEAMPLRTAIAIGAVQCIAMIPGVSRSGATIMGALLMGVER
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RTAAEFSFFLAVPTMMGATAYSLWKDRAILTFDDMNAIAIGLFVAFLVALVVVKAFVAIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
GRFGFAPFAWYRIIVGGGALLWLAWK
HHHCCHHHHHHHHHCCCCEEEEEEEH
>Mature Secondary Structure
MHDLATIILLGIIEGLTEFLPVSSTGHLILASEMLGFTGEGSAAFKIAIQLGAILAVLVA
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YRARFWGVGMGLLRADPAAVAFTRNILIGFLPAMLVGAVAYEGVRALLESPATVAVALLV
HHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GGIAILAIERMVKVVKVESVEAMPLRTAIAIGAVQCIAMIPGVSRSGATIMGALLMGVER
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
RTAAEFSFFLAVPTMMGATAYSLWKDRAILTFDDMNAIAIGLFVAFLVALVVVKAFVAIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
GRFGFAPFAWYRIIVGGGALLWLAWK
HHHCCHHHHHHHHHCCCCEEEEEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA