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The map label for this gene is galE [H]

Identifier: 103487607

GI number: 103487607

Start: 2231398

End: 2232375

Strand: Direct

Name: galE [H]

Synonym: Sala_2126

Alternate gene names: 103487607

Gene position: 2231398-2232375 (Clockwise)

Preceding gene: 103487606

Following gene: 103487608

Centisome position: 66.71

GC content: 68.3

Gene sequence:

>978_bases
ATGCGCGTTCTGCTCAGCGGATCGTCGGGATGGCTGGGACGCCATCTGGCGCCGCTGCTCGCACGAAATGGCCATGAGGT
CATCGGACTCGACGTCGTCCCCGGCGTGCATACCCACGTCGTCGGCACCGTCGCCGACCGCGCGCTGATCGAGCGGACGA
TGGGCGAGCATGGCATTGACGCCATCATTCATGGCGGCGCGCTGCACAAGCCCGACATCGCGCGACATCCGCGCCGGGCC
TTCATCGACGTCAATGTGACGGGCACGCTGAACCTGATCGAAGCGGCGGTCGCGGCGGGCAACGACCGTTTCCTCTTCAC
CTCGACCACCTCGCTGATGGTGCGCGCCGAAGTCCGCGCGGGCGCGGGCGAGCGCGGCGCGTGGTGGATGGACGAGGATT
TCGGTCCGCTGGAACCGCGCAACATCTATGGCATCACCAAGCTGGCCGCCGAGCAGGCGGTCAGGCTGGTCCACCGCGAG
CATGGGATCAACGTCGCGATCCTGCGCACCGGGCGCTTCTTTCCCGAGGATGACGATACGCACGCCGTGCCGAGCGGCCC
GAACCTGAAAGCGAATGAATTGCTCCACCGCCGCCTGACGGTCGAGGATGCCGCGGCGGCGCATCTCGCCGCGCTGGAGG
CGGCGCCGACGATTGGCTGCGATAGCTTCATCCTTTCCGCGCCGCCGCCCTTCGCACGCGACGATGCCGAGGAGCTGGCG
CGCGACGCACGCGCGGTAATCGCACGCTATCACCCCGACGCCGCCGAGCTTTATGCCGCCAAAGGCTGGGTGCTCCCCGC
GACAATCGACCGCGTTTACGACCCGTCGCGCGCCGAGCGCCGCTTCGGCTGGCGCGCCAGGAGCAACTTCGGCAGCGTGC
TCGCGGCGCTGCGCGACGGCACGCCGATGCCCTTTGCGCACGACCCCGGCTATGTCTCCCCCATGATCGCCCAGGAACGC
GAAGCATGTATGAGCTGA

Upstream 100 bases:

>100_bases
GGCGCGGTTTACGCTGTCGGCACCGCAAAAGCGTGGGACCATCTTGCACCCTGACCGGCGCCGCGGATAAGGGGCGCACA
CCACCCAGGCGGAGGATCAT

Downstream 100 bases:

>100_bases
TCACCGCCAACCGCAATTATTCGAGCTGGTCGCTGCGCCCGTGGATATTGATGAGGGGTCTGGACATCGCGTTTCGCGAC
CGCATCGAGCCCTTTACCAA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRVLLSGSSGWLGRHLAPLLARNGHEVIGLDVVPGVHTHVVGTVADRALIERTMGEHGIDAIIHGGALHKPDIARHPRRA
FIDVNVTGTLNLIEAAVAAGNDRFLFTSTTSLMVRAEVRAGAGERGAWWMDEDFGPLEPRNIYGITKLAAEQAVRLVHRE
HGINVAILRTGRFFPEDDDTHAVPSGPNLKANELLHRRLTVEDAAAAHLAALEAAPTIGCDSFILSAPPPFARDDAEELA
RDARAVIARYHPDAAELYAAKGWVLPATIDRVYDPSRAERRFGWRARSNFGSVLAALRDGTPMPFAHDPGYVSPMIAQER
EACMS

Sequences:

>Translated_325_residues
MRVLLSGSSGWLGRHLAPLLARNGHEVIGLDVVPGVHTHVVGTVADRALIERTMGEHGIDAIIHGGALHKPDIARHPRRA
FIDVNVTGTLNLIEAAVAAGNDRFLFTSTTSLMVRAEVRAGAGERGAWWMDEDFGPLEPRNIYGITKLAAEQAVRLVHRE
HGINVAILRTGRFFPEDDDTHAVPSGPNLKANELLHRRLTVEDAAAAHLAALEAAPTIGCDSFILSAPPPFARDDAEELA
RDARAVIARYHPDAAELYAAKGWVLPATIDRVYDPSRAERRFGWRARSNFGSVLAALRDGTPMPFAHDPGYVSPMIAQER
EACMS
>Mature_325_residues
MRVLLSGSSGWLGRHLAPLLARNGHEVIGLDVVPGVHTHVVGTVADRALIERTMGEHGIDAIIHGGALHKPDIARHPRRA
FIDVNVTGTLNLIEAAVAAGNDRFLFTSTTSLMVRAEVRAGAGERGAWWMDEDFGPLEPRNIYGITKLAAEQAVRLVHRE
HGINVAILRTGRFFPEDDDTHAVPSGPNLKANELLHRRLTVEDAAAAHLAALEAAPTIGCDSFILSAPPPFARDDAEELA
RDARAVIARYHPDAAELYAAKGWVLPATIDRVYDPSRAERRFGWRARSNFGSVLAALRDGTPMPFAHDPGYVSPMIAQER
EACMS

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1786974, Length=185, Percent_Identity=31.8918918918919, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35302; Mature: 35302

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLSGSSGWLGRHLAPLLARNGHEVIGLDVVPGVHTHVVGTVADRALIERTMGEHGID
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AIIHGGALHKPDIARHPRRAFIDVNVTGTLNLIEAAVAAGNDRFLFTSTTSLMVRAEVRA
EEEECCCCCCCCHHCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEEECCEEEEEEEHHC
GAGERGAWWMDEDFGPLEPRNIYGITKLAAEQAVRLVHREHGINVAILRTGRFFPEDDDT
CCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
HAVPSGPNLKANELLHRRLTVEDAAAAHLAALEAAPTIGCDSFILSAPPPFARDDAEELA
CCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHH
RDARAVIARYHPDAAELYAAKGWVLPATIDRVYDPSRAERRFGWRARSNFGSVLAALRDG
HHHHHHHHHCCCCHHHHHHHCCEECHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCC
TPMPFAHDPGYVSPMIAQEREACMS
CCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRVLLSGSSGWLGRHLAPLLARNGHEVIGLDVVPGVHTHVVGTVADRALIERTMGEHGID
CEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
AIIHGGALHKPDIARHPRRAFIDVNVTGTLNLIEAAVAAGNDRFLFTSTTSLMVRAEVRA
EEEECCCCCCCCHHCCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEEECCEEEEEEEHHC
GAGERGAWWMDEDFGPLEPRNIYGITKLAAEQAVRLVHREHGINVAILRTGRFFPEDDDT
CCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCC
HAVPSGPNLKANELLHRRLTVEDAAAAHLAALEAAPTIGCDSFILSAPPPFARDDAEELA
CCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHH
RDARAVIARYHPDAAELYAAKGWVLPATIDRVYDPSRAERRFGWRARSNFGSVLAALRDG
HHHHHHHHHCCCCHHHHHHHCCEECHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHCC
TPMPFAHDPGYVSPMIAQEREACMS
CCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3022232; 8905232; 9278503; 2134186; 8564363; 6301942; 1579570; 8611559; 8931134; 9174344; 9271499; 9708982 [H]