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The map label for this gene is 103487388

Identifier: 103487388

GI number: 103487388

Start: 2002725

End: 2003594

Strand: Direct

Name: 103487388

Synonym: Sala_1904

Alternate gene names: NA

Gene position: 2002725-2003594 (Clockwise)

Preceding gene: 103487386

Following gene: 103487390

Centisome position: 59.87

GC content: 66.9

Gene sequence:

>870_bases
ATGATCGAAGTAATGAGCCTGTTTCTGTGGCTTGCGGGTGCGGGCGGGACGCCCGTTCCGGCGATCGATCCGCTGACGCA
GCCGATCGAGACGTCACGATCGGCGGAATGGCTGGCGCCTGCGGAACCCGAAAAAATCTTTGGCAACACCTATCTTGTCG
GCTTCGCGGGGCTGAGCGTCGCACTGATCGACACGGGCGACGGGCTGGTGCTCGTCGACGGCGCGCTGCCGCAGGCGGCG
CCCGCAATCCTCGCCAATGTGCGCAAGCTCGGCTTCGACCCGCAAGACATCAAATATATTCTGAGCACCGAACCCCATTT
CGACCATGCCGGCGGCCTCGCCGCGCTCGCGCGCGACACCGGCGCGGCGGTGGTCGCAAGCGTGCGCGGCGCCGAGGGGC
TGCGCAGCGGCCGCCACGCGGCCGACGACCCGCAGCTCGGCTATGGCGGCAGTTGGCCCGCGGTCGCGAACGTCCGCACG
ATGAAGGATGGCGAAGTGCTGCGGCTTGGCACGACGGCGATCACCGCCATCGCAACGCCGGGGCACACGATGGGCAGCAT
GAGCTGGACGTGGCAGGCATGCGAGGGCCGCGTTTGCAAGGCGGTGGTGTTTGCATCGAGCCTCAATCCCGTCTCGGCCG
ATGGCTATCGCTTCACCTCCCGCGCGGGCAAACCCTTCATCAAAGGCTTTGAGGCAAGTTATCGCAAGATGGATGCGGTG
CCGTGCGACATATTGATCTCAGCGCACCCCGACAATGCGGGCAACGGGCGCTACAGCGAAAAAGCCGGCGCCTGCCGCGC
CTATGCCGACCGCTCGCGCCGCGCGCTCGCCAGGCGGCTGGCCAGCGAGCGCGTCGAAACACCGAAGTAG

Upstream 100 bases:

>100_bases
TCCATGGCTTATCATCAATTATTCTCATGGCTTTGTCGAGAAATGATGCTTTGTCGCACGGAGGGCGAACGGGCATTTTC
GATGACGAAAGGAGATGATG

Downstream 100 bases:

>100_bases
CGGACTGCGTCGCCGTTGCTGACGCGCGGCAAAAATCGCCTATCTGTCAACCACCAGACAGGCCTGACCATCCTTGCGCA
ACGACGCGCAGAATCTTTCG

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: Beta-lactamase type II; Penicillinase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MIEVMSLFLWLAGAGGTPVPAIDPLTQPIETSRSAEWLAPAEPEKIFGNTYLVGFAGLSVALIDTGDGLVLVDGALPQAA
PAILANVRKLGFDPQDIKYILSTEPHFDHAGGLAALARDTGAAVVASVRGAEGLRSGRHAADDPQLGYGGSWPAVANVRT
MKDGEVLRLGTTAITAIATPGHTMGSMSWTWQACEGRVCKAVVFASSLNPVSADGYRFTSRAGKPFIKGFEASYRKMDAV
PCDILISAHPDNAGNGRYSEKAGACRAYADRSRRALARRLASERVETPK

Sequences:

>Translated_289_residues
MIEVMSLFLWLAGAGGTPVPAIDPLTQPIETSRSAEWLAPAEPEKIFGNTYLVGFAGLSVALIDTGDGLVLVDGALPQAA
PAILANVRKLGFDPQDIKYILSTEPHFDHAGGLAALARDTGAAVVASVRGAEGLRSGRHAADDPQLGYGGSWPAVANVRT
MKDGEVLRLGTTAITAIATPGHTMGSMSWTWQACEGRVCKAVVFASSLNPVSADGYRFTSRAGKPFIKGFEASYRKMDAV
PCDILISAHPDNAGNGRYSEKAGACRAYADRSRRALARRLASERVETPK
>Mature_289_residues
MIEVMSLFLWLAGAGGTPVPAIDPLTQPIETSRSAEWLAPAEPEKIFGNTYLVGFAGLSVALIDTGDGLVLVDGALPQAA
PAILANVRKLGFDPQDIKYILSTEPHFDHAGGLAALARDTGAAVVASVRGAEGLRSGRHAADDPQLGYGGSWPAVANVRT
MKDGEVLRLGTTAITAIATPGHTMGSMSWTWQACEGRVCKAVVFASSLNPVSADGYRFTSRAGKPFIKGFEASYRKMDAV
PCDILISAHPDNAGNGRYSEKAGACRAYADRSRRALARRLASERVETPK

Specific function: Has a high activity against imipenem [H]

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 30482; Mature: 30482

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVMSLFLWLAGAGGTPVPAIDPLTQPIETSRSAEWLAPAEPEKIFGNTYLVGFAGLSV
CHHHHEEHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHCCCEEEEEECCCEE
ALIDTGDGLVLVDGALPQAAPAILANVRKLGFDPQDIKYILSTEPHFDHAGGLAALARDT
EEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHEEEECCCCCCCCCCCHHHHHHCC
GAAVVASVRGAEGLRSGRHAADDPQLGYGGSWPAVANVRTMKDGEVLRLGTTAITAIATP
CCEEEEEHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCEEEEEECC
GHTMGSMSWTWQACEGRVCKAVVFASSLNPVSADGYRFTSRAGKPFIKGFEASYRKMDAV
CCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
PCDILISAHPDNAGNGRYSEKAGACRAYADRSRRALARRLASERVETPK
CEEEEEEECCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIEVMSLFLWLAGAGGTPVPAIDPLTQPIETSRSAEWLAPAEPEKIFGNTYLVGFAGLSV
CHHHHEEHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHCCCEEEEEECCCEE
ALIDTGDGLVLVDGALPQAAPAILANVRKLGFDPQDIKYILSTEPHFDHAGGLAALARDT
EEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHEEEECCCCCCCCCCCHHHHHHCC
GAAVVASVRGAEGLRSGRHAADDPQLGYGGSWPAVANVRTMKDGEVLRLGTTAITAIATP
CCEEEEEHHCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCEEEEEECC
GHTMGSMSWTWQACEGRVCKAVVFASSLNPVSADGYRFTSRAGKPFIKGFEASYRKMDAV
CCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
PCDILISAHPDNAGNGRYSEKAGACRAYADRSRRALARRLASERVETPK
CEEEEEEECCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8018721; 3931629; 9811546 [H]