| Definition | Sphingopyxis alaskensis RB2256, complete genome. |
|---|---|
| Accession | NC_008048 |
| Length | 3,345,170 |
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The map label for this gene is fabG [H]
Identifier: 103487339
GI number: 103487339
Start: 1950195
End: 1950974
Strand: Direct
Name: fabG [H]
Synonym: Sala_1855
Alternate gene names: 103487339
Gene position: 1950195-1950974 (Clockwise)
Preceding gene: 103487335
Following gene: 103487340
Centisome position: 58.3
GC content: 68.33
Gene sequence:
>780_bases ATGAGCGACAGGAATCTTGCGGGGCGCATCGCGCTCGTTACCGGCGCCTCGCGCGGCATCGGGCGCGGCATTGCGATCGG ACTTGCGGAGGCGGGCGCCGACGTCGCGGTGAATTACACACGCGACGAAGCAGCCGCCGCCGAAACGGTCGCCGCCATTC AGGCGCTCGGCCGCAAGGCGAAGGCCTATCGGGCGTCGGTCACCGACGAAGCCGGCTGCGCCGCGATGGTCGCCGCGGTC GCTGCCGACTTCGGCGCCATGTCGATCCTCGTCAACAATGCGGGCGTCGCCAGCCGCGGGCTGTCGGTCGCCGACACCAG CCCCGAAGAGGTCGACAAGCTCTTCGCCGTCCACGCCGCCGGTCCGCACCGCCTCAGCCGCCTCGCGCTGCCACAACTGC GGAGCCATGCGCGCAGCGACATCATCATCATCTCCAGCATCGCCACCTATGTGAACGCGCCGAACGGCGCCCCCTACACG ATGGCGAAGGCGGCGGGCGAAGCGCTTGCGCTGACGCTCGCCAAGGAGGAACTGAAGAACGGTGTCCGCGTCAACATCGT CGCCCCCGCGCTCACCGTCAGCGACATGGGCGAAAAACTCTCGCGCGCGATCACCGGCGAGGACGACATCCACCATCTCG ACGCCAAAATGCCCTTCGGCCGCGTCGCCCTCCCCGCCGACGTCGCCGCCGCGGTCGTGTGGTTCGTCAGTGACGCGAAC AGCTATTGTTCGGGGCAAAAGCTCAACATCGACGGCGCGGGACAGGCGACGTTTCGGTGA
Upstream 100 bases:
>100_bases GCGAGTTCCTCGACTTCTTTTTTCCAGCTCATGGCGCGAAGCTAGCTTACGTTGACGGAAACGTCATGCCATATTCGCGC GAACGGAAAGGGAGAGGCAT
Downstream 100 bases:
>100_bases CAAGCATCGTCATTGCGCGGAGCCGCAGACGACGCGGCAATCCGGAGCAGGCGTAAACCGCTCTGGATTGGTTGGCCTGC GATCGCCTTCGGCCCGCACC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MSDRNLAGRIALVTGASRGIGRGIAIGLAEAGADVAVNYTRDEAAAAETVAAIQALGRKAKAYRASVTDEAGCAAMVAAV AADFGAMSILVNNAGVASRGLSVADTSPEEVDKLFAVHAAGPHRLSRLALPQLRSHARSDIIIISSIATYVNAPNGAPYT MAKAAGEALALTLAKEELKNGVRVNIVAPALTVSDMGEKLSRAITGEDDIHHLDAKMPFGRVALPADVAAAVVWFVSDAN SYCSGQKLNIDGAGQATFR
Sequences:
>Translated_259_residues MSDRNLAGRIALVTGASRGIGRGIAIGLAEAGADVAVNYTRDEAAAAETVAAIQALGRKAKAYRASVTDEAGCAAMVAAV AADFGAMSILVNNAGVASRGLSVADTSPEEVDKLFAVHAAGPHRLSRLALPQLRSHARSDIIIISSIATYVNAPNGAPYT MAKAAGEALALTLAKEELKNGVRVNIVAPALTVSDMGEKLSRAITGEDDIHHLDAKMPFGRVALPADVAAAVVWFVSDAN SYCSGQKLNIDGAGQATFR >Mature_258_residues SDRNLAGRIALVTGASRGIGRGIAIGLAEAGADVAVNYTRDEAAAAETVAAIQALGRKAKAYRASVTDEAGCAAMVAAVA ADFGAMSILVNNAGVASRGLSVADTSPEEVDKLFAVHAAGPHRLSRLALPQLRSHARSDIIIISSIATYVNAPNGAPYTM AKAAGEALALTLAKEELKNGVRVNIVAPALTVSDMGEKLSRAITGEDDIHHLDAKMPFGRVALPADVAAAVVWFVSDANS YCSGQKLNIDGAGQATFR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=29.2490118577075, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=31.3492063492063, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI59889578, Length=193, Percent_Identity=30.5699481865285, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI4504505, Length=240, Percent_Identity=31.6666666666667, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.0395256916996, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=27.9352226720648, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=30.3191489361702, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=31.6062176165803, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=24.609375, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI40254986, Length=192, Percent_Identity=30.7291666666667, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI142976729, Length=189, Percent_Identity=27.5132275132275, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=33.8709677419355, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=31.8548387096774, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=31.6205533596838, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=29.1338582677165, Blast_Score=101, Evalue=6e-23, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=32.9317269076305, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=26.9387755102041, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=27.34375, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=27.6679841897233, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=28.9156626506024, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=25.7692307692308, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=28.6852589641434, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=31.1538461538462, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=30.1587301587302, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=31.1538461538462, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=30.9917355371901, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=31.5384615384615, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=30.7086614173228, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=30.5019305019305, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=31.8007662835249, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=29.8449612403101, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=27.3062730627306, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=30.5343511450382, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.5471698113208, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=27.3764258555133, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=30.8880308880309, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17562990, Length=258, Percent_Identity=28.6821705426357, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=29.4339622641509, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=27.8625954198473, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=29.4573643410853, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17568967, Length=205, Percent_Identity=31.219512195122, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=26.615969581749, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI71982365, Length=197, Percent_Identity=30.9644670050761, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=28.8461538461538, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17563726, Length=257, Percent_Identity=28.0155642023346, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=28, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17538182, Length=262, Percent_Identity=27.4809160305344, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17558628, Length=194, Percent_Identity=30.4123711340206, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI32563809, Length=192, Percent_Identity=25.5208333333333, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17507613, Length=192, Percent_Identity=25.5208333333333, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17508895, Length=199, Percent_Identity=26.1306532663317, Blast_Score=64, Evalue=8e-11, Organism=Caenorhabditis elegans, GI193203117, Length=187, Percent_Identity=25.668449197861, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6322861, Length=200, Percent_Identity=33.5, Blast_Score=83, Evalue=5e-17, Organism=Saccharomyces cerevisiae, GI6322227, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=26, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=32.156862745098, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=28.8617886178862, Blast_Score=97, Evalue=9e-21, Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=29.6875, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=29.1828793774319, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI24649181, Length=216, Percent_Identity=31.4814814814815, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.8725099601594, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21356301, Length=194, Percent_Identity=31.9587628865979, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI281364892, Length=196, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=35.2631578947368, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=32.994923857868, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=29.1828793774319, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI21355631, Length=177, Percent_Identity=27.1186440677966, Blast_Score=68, Evalue=6e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26563; Mature: 26432
Theoretical pI: Translated: 7.06; Mature: 7.06
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSDRNLAGRIALVTGASRGIGRGIAIGLAEAGADVAVNYTRDEAAAAETVAAIQALGRKA CCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHH KAYRASVTDEAGCAAMVAAVAADFGAMSILVNNAGVASRGLSVADTSPEEVDKLFAVHAA HHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC GPHRLSRLALPQLRSHARSDIIIISSIATYVNAPNGAPYTMAKAAGEALALTLAKEELKN CHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCHHHHHCCCHHHHHEEHHHHHC GVRVNIVAPALTVSDMGEKLSRAITGEDDIHHLDAKMPFGRVALPADVAAAVVWFVSDAN CCEEEEEECCHHHHHHHHHHHHHCCCCCCHHEECCCCCCCCEECCHHHHHHHHHHHHCCC SYCSGQKLNIDGAGQATFR CCCCCCEEECCCCCCCCCC >Mature Secondary Structure SDRNLAGRIALVTGASRGIGRGIAIGLAEAGADVAVNYTRDEAAAAETVAAIQALGRKA CCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHH KAYRASVTDEAGCAAMVAAVAADFGAMSILVNNAGVASRGLSVADTSPEEVDKLFAVHAA HHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC GPHRLSRLALPQLRSHARSDIIIISSIATYVNAPNGAPYTMAKAAGEALALTLAKEELKN CHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCCHHHHHCCCHHHHHEEHHHHHC GVRVNIVAPALTVSDMGEKLSRAITGEDDIHHLDAKMPFGRVALPADVAAAVVWFVSDAN CCEEEEEECCHHHHHHHHHHHHHCCCCCCHHEECCCCCCCCEECCHHHHHHHHHHHHCCC SYCSGQKLNIDGAGQATFR CCCCCCEEECCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]