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The map label for this gene is fadE12 [H]

Identifier: 103487177

GI number: 103487177

Start: 1782267

End: 1783430

Strand: Direct

Name: fadE12 [H]

Synonym: Sala_1692

Alternate gene names: 103487177

Gene position: 1782267-1783430 (Clockwise)

Preceding gene: 103487176

Following gene: 103487178

Centisome position: 53.28

GC content: 64.35

Gene sequence:

>1164_bases
ATGTCCGAAGCCGACCAACAAAGCCATCCCGAAATCCGCGAGGCGGTGCGCCGCCTCTGCGCCGGTTTTCCGGGCGATTA
TTGGCAACGGCTCGACCGCGAGCGCATTTATCCGACCGAGTTCGTGCGTACGCTGACCGAAGCGGGTTTTCTCTCGGTGC
TGATCCCCGAACAATATGGCGGATCGGGCCTCGGCCTCGGCGCGGCGACCGCGGTGCTCGAGGAAATCCACCGGTCGGGC
TGCAATGGCGGCGCCTGCCATGCGCAGATGTATACGATGGGTACCTTGCTCAAGCACGGGTCGGAGGCGCAGAAACAGGC
CTATCTGCCCGCGATCGCGCGCGGCGAGCTGCGCCTGCAGGCCTTCGGCGTCACCGAGCCGACCGCGGGCACTGACACCA
CGCGCATCCGCACCTTCGCGCGCAAGGTCGGCGACAAATATGTGGTCAATGGGCAGAAGATCTGGATCAGCCGAGCCGAA
CATTCGGACCTGATGGTCCTGCTCTGCCGCACAACGCCGCGCGACGAATGCGCCAAGCCGTCGGACGGGATGAGCGTACT
GCTCGTCGACATGCGCGAGGCGGTGGGCAAGGGCCTCACCATCCGTCCTCTGCGCACGATGCTCAACCATGCGACGACCG
AGCTCTTTTTCGACGATCTCGAAGTTCCTGCCGCCAATTTGATCGGCGAGGAGGGCCGGGGGTTTCGCTATATCCTGTCG
GGCATGAACGCCGAGCGTATCCTGATCGCGTCGGAATGTATCGGCGACGGCCGCTTCTTCGTCGACCGCGCCACCGCATA
CGCCAGGGACCGCTCGGTCTTTGGCCGCCCGATCGGCGAAAACCAGGGCATCCAGTTCCCCATCGCACGCGCTTATGTCC
AGATCGCCGCCGCTGCCGAGATGGTGGCCAAGGCGGCGCGCCTCTTCGACGCAGGCGCCGACTGCGGAACCGAGGCGAAT
ATGGCGAAGATGCTCGCGTCGGAGGCGAGCTGGTATGCCGCCGACATGTGCCTTCAGACGCACGGCGGCTTCGGTTTTGC
CGAGGAATATGACATCGAGCGCAAGTTCCGCGAAACCCGGCTCTATCAGGTCGCGCCGATCAGCACGAACCTCATCCTCA
GCCATGTCGCAACGCACGCGCTTGGCCTGCCCAAGAGCTTCTGA

Upstream 100 bases:

>100_bases
GGGCCTCGACCTGCCAAGCATCTGACGCTTGTTTCGGTTGCACCAAAACAGCTTCGTATCCTAAGGCTCTCTCCGACGAT
CAGGGGAGAGCCGAACGCCG

Downstream 100 bases:

>100_bases
TGGACGATTATTCCGCCTGGATCGGCCGCGGTGAAACGCGCGAGGATGTCGCGACTGCGGTGCCGATCGAAGGCCTCGCC
GCTCTGCTCGACCACGACGC

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSEADQQSHPEIREAVRRLCAGFPGDYWQRLDRERIYPTEFVRTLTEAGFLSVLIPEQYGGSGLGLGAATAVLEEIHRSG
CNGGACHAQMYTMGTLLKHGSEAQKQAYLPAIARGELRLQAFGVTEPTAGTDTTRIRTFARKVGDKYVVNGQKIWISRAE
HSDLMVLLCRTTPRDECAKPSDGMSVLLVDMREAVGKGLTIRPLRTMLNHATTELFFDDLEVPAANLIGEEGRGFRYILS
GMNAERILIASECIGDGRFFVDRATAYARDRSVFGRPIGENQGIQFPIARAYVQIAAAAEMVAKAARLFDAGADCGTEAN
MAKMLASEASWYAADMCLQTHGGFGFAEEYDIERKFRETRLYQVAPISTNLILSHVATHALGLPKSF

Sequences:

>Translated_387_residues
MSEADQQSHPEIREAVRRLCAGFPGDYWQRLDRERIYPTEFVRTLTEAGFLSVLIPEQYGGSGLGLGAATAVLEEIHRSG
CNGGACHAQMYTMGTLLKHGSEAQKQAYLPAIARGELRLQAFGVTEPTAGTDTTRIRTFARKVGDKYVVNGQKIWISRAE
HSDLMVLLCRTTPRDECAKPSDGMSVLLVDMREAVGKGLTIRPLRTMLNHATTELFFDDLEVPAANLIGEEGRGFRYILS
GMNAERILIASECIGDGRFFVDRATAYARDRSVFGRPIGENQGIQFPIARAYVQIAAAAEMVAKAARLFDAGADCGTEAN
MAKMLASEASWYAADMCLQTHGGFGFAEEYDIERKFRETRLYQVAPISTNLILSHVATHALGLPKSF
>Mature_386_residues
SEADQQSHPEIREAVRRLCAGFPGDYWQRLDRERIYPTEFVRTLTEAGFLSVLIPEQYGGSGLGLGAATAVLEEIHRSGC
NGGACHAQMYTMGTLLKHGSEAQKQAYLPAIARGELRLQAFGVTEPTAGTDTTRIRTFARKVGDKYVVNGQKIWISRAEH
SDLMVLLCRTTPRDECAKPSDGMSVLLVDMREAVGKGLTIRPLRTMLNHATTELFFDDLEVPAANLIGEEGRGFRYILSG
MNAERILIASECIGDGRFFVDRATAYARDRSVFGRPIGENQGIQFPIARAYVQIAAAAEMVAKAARLFDAGADCGTEANM
AKMLASEASWYAADMCLQTHGGFGFAEEYDIERKFRETRLYQVAPISTNLILSHVATHALGLPKSF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=29.7587131367292, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI4557233, Length=358, Percent_Identity=31.5642458100559, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4501857, Length=334, Percent_Identity=33.8323353293413, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI226958412, Length=349, Percent_Identity=31.2320916905444, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=31.547619047619, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI7656849, Length=337, Percent_Identity=30.8605341246291, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI187960098, Length=340, Percent_Identity=31.7647058823529, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI4557231, Length=340, Percent_Identity=31.7647058823529, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI4557235, Length=342, Percent_Identity=31.2865497076023, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI76496475, Length=342, Percent_Identity=31.2865497076023, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI21361497, Length=361, Percent_Identity=27.9778393351801, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI7669494, Length=334, Percent_Identity=29.3413173652695, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4503943, Length=334, Percent_Identity=29.3413173652695, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=30.6620209059233, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=30.6620209059233, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38505218, Length=298, Percent_Identity=27.1812080536913, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=29.7082228116711, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1786223, Length=339, Percent_Identity=27.7286135693215, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17508101, Length=367, Percent_Identity=28.3378746594005, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17534899, Length=342, Percent_Identity=30.7017543859649, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17506239, Length=336, Percent_Identity=29.4642857142857, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=341, Percent_Identity=31.0850439882698, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17569725, Length=364, Percent_Identity=28.5714285714286, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17505929, Length=343, Percent_Identity=31.1953352769679, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=370, Percent_Identity=29.7297297297297, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17538396, Length=373, Percent_Identity=27.8820375335121, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17551932, Length=343, Percent_Identity=28.8629737609329, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=303, Percent_Identity=31.6831683168317, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17533517, Length=341, Percent_Identity=30.791788856305, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=315, Percent_Identity=29.2063492063492, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=239, Percent_Identity=28.0334728033473, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17534353, Length=340, Percent_Identity=28.2352941176471, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=23.8095238095238, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=26.7489711934156, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562446, Length=307, Percent_Identity=27.3615635179153, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=270, Percent_Identity=27.4074074074074, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=270, Percent_Identity=27.4074074074074, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21356377, Length=364, Percent_Identity=31.5934065934066, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=30.3763440860215, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24646207, Length=342, Percent_Identity=30.1169590643275, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24660351, Length=342, Percent_Identity=30.1169590643275, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=30.8823529411765, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21355753, Length=336, Percent_Identity=30.3571428571429, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI19920834, Length=354, Percent_Identity=29.0960451977401, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42528; Mature: 42397

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEADQQSHPEIREAVRRLCAGFPGDYWQRLDRERIYPTEFVRTLTEAGFLSVLIPEQYG
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GSGLGLGAATAVLEEIHRSGCNGGACHAQMYTMGTLLKHGSEAQKQAYLPAIARGELRLQ
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCEEEE
AFGVTEPTAGTDTTRIRTFARKVGDKYVVNGQKIWISRAEHSDLMVLLCRTTPRDECAKP
EECCCCCCCCCCHHHHHHHHHHHCCEEEECCEEEEEEECCCCCEEEEEECCCCHHHCCCC
SDGMSVLLVDMREAVGKGLTIRPLRTMLNHATTELFFDDLEVPAANLIGEEGRGFRYILS
CCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHCC
GMNAERILIASECIGDGRFFVDRATAYARDRSVFGRPIGENQGIQFPIARAYVQIAAAAE
CCCCCEEEEEHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
MVAKAARLFDAGADCGTEANMAKMLASEASWYAADMCLQTHGGFGFAEEYDIERKFRETR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LYQVAPISTNLILSHVATHALGLPKSF
CEEEECCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEADQQSHPEIREAVRRLCAGFPGDYWQRLDRERIYPTEFVRTLTEAGFLSVLIPEQYG
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCC
GSGLGLGAATAVLEEIHRSGCNGGACHAQMYTMGTLLKHGSEAQKQAYLPAIARGELRLQ
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHHCCCEEEE
AFGVTEPTAGTDTTRIRTFARKVGDKYVVNGQKIWISRAEHSDLMVLLCRTTPRDECAKP
EECCCCCCCCCCHHHHHHHHHHHCCEEEECCEEEEEEECCCCCEEEEEECCCCHHHCCCC
SDGMSVLLVDMREAVGKGLTIRPLRTMLNHATTELFFDDLEVPAANLIGEEGRGFRYILS
CCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHCC
GMNAERILIASECIGDGRFFVDRATAYARDRSVFGRPIGENQGIQFPIARAYVQIAAAAE
CCCCCEEEEEHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
MVAKAARLFDAGADCGTEANMAKMLASEASWYAADMCLQTHGGFGFAEEYDIERKFRETR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LYQVAPISTNLILSHVATHALGLPKSF
CEEEECCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]