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The map label for this gene is aroC

Identifier: 103486152

GI number: 103486152

Start: 669359

End: 670435

Strand: Direct

Name: aroC

Synonym: Sala_0659

Alternate gene names: 103486152

Gene position: 669359-670435 (Clockwise)

Preceding gene: 103486151

Following gene: 103486153

Centisome position: 20.01

GC content: 68.25

Gene sequence:

>1077_bases
ATGAGTTTCAACAGCTTCGGACGCGTCCTGCGCTTTACGACCTGGGGGGAAAGTCACGGGCCCGCGCTCGGTGCGGTCGT
CGATGGCTGCCCGCCGCGGCTGTCTCTGTCCGAAGCCGACATCCAGCCCTTTCTCGACAAGCGTCGCCCCGGCCAGTCGC
GCCACACCACGCAGCGGCAGGAGCCCGACCAGGTGCGTATCCTGTCGGGGGTGTTCGAAGGCAAGACGACAGGCACGCCG
ATCAGCCTGATGATCGAGAATGTCGATCAGCGATCGAAGGATTATGGCGAGATCGCGCAAGCCTGGCGTCCCGGCCACGC
CGATTATGCCTATGACGCCAAATATGGCATCCGCGATTATCGCGGCGGCGGCCGGTCGAGCGCGCGCGAGACTGCGGCGC
GTGTCGCGGCGGGCGCTGTCGCGCGGCTGGTGATCCCGGAGGTGCAGATCCACGCCTGGGTCGCGGAGATCGGCGGCGAT
GCGATCGATCCGGCGAACTTCGACCTCGAAGAAATCGATCGCAATCCCTTTTTCTGTCCCGACCCCGCGGCGGCGCAGCG
CTGGGAGGCGCTGATGGATTCCGCGCGCAAGGCGGGAAGCTCGCTGGGCGCGGTCATCGAATGCGCCGCGAGCGGCGTCC
CCGCAGGCTGGGGCGCGCCTGTCTATGCCAAGCTCGACAGTGACCTTGCGGCCGCGATGATGGGGATCAACGCGGTGAAG
GGCGTCGAGATCGGCGCGGGATTCGGCGTGGCGCGGCTGCGCGGCGAGGAAAATGCCGATCCGATGCGCCCCGCCAGCGA
CGGCAGCAACCGCCCCGATTTCCTGTCGAACAATGCCGGCGGCATCGCGGGCGGCATTTCGACCGGGCAGCCGGTCGTCG
TGCGCGTCGCCTTCAAGCCGACGAGTTCGATCCTGACCCCGGTGCCGACGGTGAACAAGGCGGGCGAGGCGACCGACATC
GTGACCAGGGGCCGCCACGACCCCTGCGTCGGCATCCGCGGCGCGCCGGTGGTCGAAGCGATGATGGCGCTGACACTCGC
CGACCACAAGCTGCTCCACCGCGCGCAGTGCGGATGA

Upstream 100 bases:

>100_bases
CGACCAAAGATGACAGCCCGGTCGAGGGGCGCTACCGTTTTTTTGCAGAAGACCCTTTCGGCAATCGAATCGAGTTTATG
GACAGGGTGGCACGGGGCAT

Downstream 100 bases:

>100_bases
CGGGTCCGTGATCGACGTCGCCCGCACCTTTATCACCAATCATCAGGCGATCATCGGCCTCGTCGTCCTGGGCCTGATGT
TCGTCGGTTTCGTTCTGGAG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSFNSFGRVLRFTTWGESHGPALGAVVDGCPPRLSLSEADIQPFLDKRRPGQSRHTTQRQEPDQVRILSGVFEGKTTGTP
ISLMIENVDQRSKDYGEIAQAWRPGHADYAYDAKYGIRDYRGGGRSSARETAARVAAGAVARLVIPEVQIHAWVAEIGGD
AIDPANFDLEEIDRNPFFCPDPAAAQRWEALMDSARKAGSSLGAVIECAASGVPAGWGAPVYAKLDSDLAAAMMGINAVK
GVEIGAGFGVARLRGEENADPMRPASDGSNRPDFLSNNAGGIAGGISTGQPVVVRVAFKPTSSILTPVPTVNKAGEATDI
VTRGRHDPCVGIRGAPVVEAMMALTLADHKLLHRAQCG

Sequences:

>Translated_358_residues
MSFNSFGRVLRFTTWGESHGPALGAVVDGCPPRLSLSEADIQPFLDKRRPGQSRHTTQRQEPDQVRILSGVFEGKTTGTP
ISLMIENVDQRSKDYGEIAQAWRPGHADYAYDAKYGIRDYRGGGRSSARETAARVAAGAVARLVIPEVQIHAWVAEIGGD
AIDPANFDLEEIDRNPFFCPDPAAAQRWEALMDSARKAGSSLGAVIECAASGVPAGWGAPVYAKLDSDLAAAMMGINAVK
GVEIGAGFGVARLRGEENADPMRPASDGSNRPDFLSNNAGGIAGGISTGQPVVVRVAFKPTSSILTPVPTVNKAGEATDI
VTRGRHDPCVGIRGAPVVEAMMALTLADHKLLHRAQCG
>Mature_357_residues
SFNSFGRVLRFTTWGESHGPALGAVVDGCPPRLSLSEADIQPFLDKRRPGQSRHTTQRQEPDQVRILSGVFEGKTTGTPI
SLMIENVDQRSKDYGEIAQAWRPGHADYAYDAKYGIRDYRGGGRSSARETAARVAAGAVARLVIPEVQIHAWVAEIGGDA
IDPANFDLEEIDRNPFFCPDPAAAQRWEALMDSARKAGSSLGAVIECAASGVPAGWGAPVYAKLDSDLAAAMMGINAVKG
VEIGAGFGVARLRGEENADPMRPASDGSNRPDFLSNNAGGIAGGISTGQPVVVRVAFKPTSSILTPVPTVNKAGEATDIV
TRGRHDPCVGIRGAPVVEAMMALTLADHKLLHRAQCG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=56.2674094707521, Blast_Score=388, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=42.8184281842818, Blast_Score=288, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_SPHAL (Q1GVE2)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615713.1
- ProteinModelPortal:   Q1GVE2
- SMR:   Q1GVE2
- GeneID:   4082749
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0659
- NMPDR:   fig|317655.9.peg.612
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   SALA317655:SALA_0659-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 37867; Mature: 37736

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNSFGRVLRFTTWGESHGPALGAVVDGCPPRLSLSEADIQPFLDKRRPGQSRHTTQRQ
CCCCHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDQVRILSGVFEGKTTGTPISLMIENVDQRSKDYGEIAQAWRPGHADYAYDAKYGIRDY
CCCHHHHHHHHHCCCCCCCCHHHEEHHHHHHCHHHHHHHHHHCCCCCCCEECCCCCCHHC
RGGGRSSARETAARVAAGAVARLVIPEVQIHAWVAEIGGDAIDPANFDLEEIDRNPFFCP
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCC
DPAAAQRWEALMDSARKAGSSLGAVIECAASGVPAGWGAPVYAKLDSDLAAAMMGINAVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHC
GVEIGAGFGVARLRGEENADPMRPASDGSNRPDFLSNNAGGIAGGISTGQPVVVRVAFKP
CEEECCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEECC
TSSILTPVPTVNKAGEATDIVTRGRHDPCVGIRGAPVVEAMMALTLADHKLLHRAQCG
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFNSFGRVLRFTTWGESHGPALGAVVDGCPPRLSLSEADIQPFLDKRRPGQSRHTTQRQ
CCCHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDQVRILSGVFEGKTTGTPISLMIENVDQRSKDYGEIAQAWRPGHADYAYDAKYGIRDY
CCCHHHHHHHHHCCCCCCCCHHHEEHHHHHHCHHHHHHHHHHCCCCCCCEECCCCCCHHC
RGGGRSSARETAARVAAGAVARLVIPEVQIHAWVAEIGGDAIDPANFDLEEIDRNPFFCP
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCC
DPAAAQRWEALMDSARKAGSSLGAVIECAASGVPAGWGAPVYAKLDSDLAAAMMGINAVK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHC
GVEIGAGFGVARLRGEENADPMRPASDGSNRPDFLSNNAGGIAGGISTGQPVVVRVAFKP
CEEECCCCCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEECC
TSSILTPVPTVNKAGEATDIVTRGRHDPCVGIRGAPVVEAMMALTLADHKLLHRAQCG
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA