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The map label for this gene is tdk [H]

Identifier: 103486031

GI number: 103486031

Start: 553000

End: 553593

Strand: Direct

Name: tdk [H]

Synonym: Sala_0538

Alternate gene names: 103486031

Gene position: 553000-553593 (Clockwise)

Preceding gene: 103486029

Following gene: 103486032

Centisome position: 16.53

GC content: 63.8

Gene sequence:

>594_bases
ATGGCCAAGCTCTACTTTTATTATGCCAGCATGAACGCCGGCAAATCGACGACGCTGCTGCAGGCGGATTTCAACTATCG
CGAGCGCGGCATGGAAACAATGCTGTGGACCGCGGCGCTCGACGACCGCTACGGCACGGGGCAGGTGACGAGCCGGATCG
GCTTGATGGCGGCGGCACACAAGTTTGATCCCGAAAGCGATCTGTTCGCCGCGGTGAGCGCCGAAAATGCGGAACGGCCG
CTGGCCTGCGTGCTTGTCGACGAGGCGCAATTCCTGTCGCGTGAGCAGGTGTTGCAACTGGCGCGGCTCGCCGATGAGGT
GAATATCCCGGTGCTCTGTTACGGCCTGCGCACCGATTTCGCCGCGAACCTGTTTCCCGGCTCGGCGGCGCTGCTCGGCC
TTGCCGACGCGCTCGTCGAACTCAAAGCCGTGTGCGAATGCGGGCGCAAGGCGACGATGAACCTGCGCGTCGATGAAAAC
GGCCGCGCGGTGGTCGAAGGCGCGCAGACCGAGATCGGCGGCAACGACCGCTATGTCGCGATGTGTCGGCGGCATTTCAT
GGAAAAGCGACGCGAGGCGGCCGCGGATGCTTGA

Upstream 100 bases:

>100_bases
CGCCCTTTTGCGGCGGCGTGGCGGCGGCACTGCTGTCGGTCATCCCTGTTCCCTTTTTTGATCGTCTTGTCGTTCGCGTG
GCGCCGACTATAGCCGGGCC

Downstream 100 bases:

>100_bases
CCGGCTCTATGTCGAGCTGACCGAGGGCGACCTTCGGCTCGTCAAGCTCGCCGAAGCACACCGCGAGGCGCTGCGCGCCG
CTTGCGCCGCCGATGGCGAC

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MAKLYFYYASMNAGKSTTLLQADFNYRERGMETMLWTAALDDRYGTGQVTSRIGLMAAAHKFDPESDLFAAVSAENAERP
LACVLVDEAQFLSREQVLQLARLADEVNIPVLCYGLRTDFAANLFPGSAALLGLADALVELKAVCECGRKATMNLRVDEN
GRAVVEGAQTEIGGNDRYVAMCRRHFMEKRREAAADA

Sequences:

>Translated_197_residues
MAKLYFYYASMNAGKSTTLLQADFNYRERGMETMLWTAALDDRYGTGQVTSRIGLMAAAHKFDPESDLFAAVSAENAERP
LACVLVDEAQFLSREQVLQLARLADEVNIPVLCYGLRTDFAANLFPGSAALLGLADALVELKAVCECGRKATMNLRVDEN
GRAVVEGAQTEIGGNDRYVAMCRRHFMEKRREAAADA
>Mature_196_residues
AKLYFYYASMNAGKSTTLLQADFNYRERGMETMLWTAALDDRYGTGQVTSRIGLMAAAHKFDPESDLFAAVSAENAERPL
ACVLVDEAQFLSREQVLQLARLADEVNIPVLCYGLRTDFAANLFPGSAALLGLADALVELKAVCECGRKATMNLRVDENG
RAVVEGAQTEIGGNDRYVAMCRRHFMEKRREAAADA

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=188, Percent_Identity=57.4468085106383, Blast_Score=241, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21673; Mature: 21542

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYFYYASMNAGKSTTLLQADFNYRERGMETMLWTAALDDRYGTGQVTSRIGLMAAAH
CCEEEEEEEECCCCCCEEEEEECCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KFDPESDLFAAVSAENAERPLACVLVDEAQFLSREQVLQLARLADEVNIPVLCYGLRTDF
CCCCCCCEEEEEECCCCCCCEEEEEECCHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCC
AANLFPGSAALLGLADALVELKAVCECGRKATMNLRVDENGRAVVEGAQTEIGGNDRYVA
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHH
MCRRHFMEKRREAAADA
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKLYFYYASMNAGKSTTLLQADFNYRERGMETMLWTAALDDRYGTGQVTSRIGLMAAAH
CEEEEEEEECCCCCCEEEEEECCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KFDPESDLFAAVSAENAERPLACVLVDEAQFLSREQVLQLARLADEVNIPVLCYGLRTDF
CCCCCCCEEEEEECCCCCCCEEEEEECCHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCC
AANLFPGSAALLGLADALVELKAVCECGRKATMNLRVDENGRAVVEGAQTEIGGNDRYVA
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCCCHHHH
MCRRHFMEKRREAAADA
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA