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The map label for this gene is aatC [H]

Identifier: 103485999

GI number: 103485999

Start: 523927

End: 525147

Strand: Direct

Name: aatC [H]

Synonym: Sala_0506

Alternate gene names: 103485999

Gene position: 523927-525147 (Clockwise)

Preceding gene: 103485995

Following gene: 103486000

Centisome position: 15.66

GC content: 64.86

Gene sequence:

>1221_bases
ATGTCCGACGATGAATTCTATCGCATCAAGCGCCTGCCGCCCTATGTCATCGCCGAAGTCAATGCGATGCGTGCGGCCGC
GCGTGCCGCGGGCGAGGATATCATCGACCTGGGGATGGGCAACCCCGACCTGCCGCCGCCCGACCATGTGATCGACAAAT
TGTGCGAAGTCGCGCGCAAGCCCGATGCCCACGGCTATTCGCAGTCGAAAGGCATCCCCGGTCTGCGTCGCGCGCAGGCC
AATTATTACGGCCGCCGCTTCAACGTCGACCTCGACCCCGAAAGCGAAGTGGTGGTGACGATGGGGTCGAAGGAGGGGCT
CGCGAGCCTCGCGACCGCGATCACCGGCCCCGGCGACGTCGTGCTCGCGCCGAACCCCAGCTATCCCATTCACACCTTCG
GCTTCATCATCGCCGGCGCGACGATCCGCAGCGTGCCGACGACGCCCGACGAGAATTACTGGCGCGCGCTCGACCGCGCG
ATGGCCTTCACCGTGCCGCGCCCGTCGATCCTGGTGGTCAATTATCCCTCGAACCCGACCGCCGAGGCGGTCGATCTCGC
TTTTTACGAACGTCTTGTCGCCTGGGCGAAGGAGAATAAGGTCTGGGTGCTCAGCGATCTTGCCTATTCGGAGCTTTATT
ACGACGGCAACCCGACGCCCTCGATCCTGCAGGTGCCGGGCGCGAAGGACGTCGCGATCGAGTTCACGTCGATGTCCAAA
ACCTATTCGATGGCGGGCTGGCGCATGGGCTTTGCGGTCGGCAACAAGCGGCTGATCGCCGCGATGACGCGCGTCAAATC
CTATCTCGACTATGGCGCCTTCACCCCCATTCAGGCCGCGGCGTGCGCGGCGCTCAACGGGCCGCAGGACATCGTCGAGA
AGAACCGCCAGCTCTATCAGAAGCGCCGCGACGTGATGGTCGAAAGCTTCGGCCGAGCGGGATGGGACATCCCCAGCCCG
CCCGCGTCGATGTTCGCCTGGGCGCCGCTGCCGCCCGCGCTCAGGGAGATGGGCAGCCTCGAGTTTTCCAAACAGCTGCT
GACCCACGCCAAGGTCGCGGTCGCCCCCGGCGTTGGTTATGGCGAGGATGGCGAGGGCTTTGTCCGCATCGCGATGGTCG
AAAATGAACAGCGCATCCGGCAGGCGGCGCGCAACATCCGCAAGTTTCTGGCCATGCACGGCGTGAACACACCTTCGATC
GCCGCCGGCGGCGCGGGATAA

Upstream 100 bases:

>100_bases
CAGTGCCGTGAGAATCCCTATAACAAGCCGCGTCGCGGCTGGCGAGGTTGCCGCTCGCGTCAATTCAAACGCATACGTAA
AGGAGTTGTTCTAGTTTCCC

Downstream 100 bases:

>100_bases
ATGAGCCTCGACGCGAGCGCCATCGCGCAGACGATCCAGCTGTCGGTCACGCCGGTGTTCCTGCTGGTGGCGACCGGCAG
CCTGCTGAACGTCATCGCGG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSDDEFYRIKRLPPYVIAEVNAMRAAARAAGEDIIDLGMGNPDLPPPDHVIDKLCEVARKPDAHGYSQSKGIPGLRRAQA
NYYGRRFNVDLDPESEVVVTMGSKEGLASLATAITGPGDVVLAPNPSYPIHTFGFIIAGATIRSVPTTPDENYWRALDRA
MAFTVPRPSILVVNYPSNPTAEAVDLAFYERLVAWAKENKVWVLSDLAYSELYYDGNPTPSILQVPGAKDVAIEFTSMSK
TYSMAGWRMGFAVGNKRLIAAMTRVKSYLDYGAFTPIQAAACAALNGPQDIVEKNRQLYQKRRDVMVESFGRAGWDIPSP
PASMFAWAPLPPALREMGSLEFSKQLLTHAKVAVAPGVGYGEDGEGFVRIAMVENEQRIRQAARNIRKFLAMHGVNTPSI
AAGGAG

Sequences:

>Translated_406_residues
MSDDEFYRIKRLPPYVIAEVNAMRAAARAAGEDIIDLGMGNPDLPPPDHVIDKLCEVARKPDAHGYSQSKGIPGLRRAQA
NYYGRRFNVDLDPESEVVVTMGSKEGLASLATAITGPGDVVLAPNPSYPIHTFGFIIAGATIRSVPTTPDENYWRALDRA
MAFTVPRPSILVVNYPSNPTAEAVDLAFYERLVAWAKENKVWVLSDLAYSELYYDGNPTPSILQVPGAKDVAIEFTSMSK
TYSMAGWRMGFAVGNKRLIAAMTRVKSYLDYGAFTPIQAAACAALNGPQDIVEKNRQLYQKRRDVMVESFGRAGWDIPSP
PASMFAWAPLPPALREMGSLEFSKQLLTHAKVAVAPGVGYGEDGEGFVRIAMVENEQRIRQAARNIRKFLAMHGVNTPSI
AAGGAG
>Mature_405_residues
SDDEFYRIKRLPPYVIAEVNAMRAAARAAGEDIIDLGMGNPDLPPPDHVIDKLCEVARKPDAHGYSQSKGIPGLRRAQAN
YYGRRFNVDLDPESEVVVTMGSKEGLASLATAITGPGDVVLAPNPSYPIHTFGFIIAGATIRSVPTTPDENYWRALDRAM
AFTVPRPSILVVNYPSNPTAEAVDLAFYERLVAWAKENKVWVLSDLAYSELYYDGNPTPSILQVPGAKDVAIEFTSMSKT
YSMAGWRMGFAVGNKRLIAAMTRVKSYLDYGAFTPIQAAACAALNGPQDIVEKNRQLYQKRRDVMVESFGRAGWDIPSPP
ASMFAWAPLPPALREMGSLEFSKQLLTHAKVAVAPGVGYGEDGEGFVRIAMVENEQRIRQAARNIRKFLAMHGVNTPSIA
AGGAG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=389, Percent_Identity=24.9357326478149, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI56713254, Length=389, Percent_Identity=24.9357326478149, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=23.5443037974684, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=23.5443037974684, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI169881281, Length=385, Percent_Identity=21.8181818181818, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=53.0769230769231, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=23.9130434782609, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788627, Length=286, Percent_Identity=29.020979020979, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788332, Length=211, Percent_Identity=27.0142180094787, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=398, Percent_Identity=25.6281407035176, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=398, Percent_Identity=25.6281407035176, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=394, Percent_Identity=22.3350253807107, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=395, Percent_Identity=21.7721518987342, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=21.9638242894057, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573069, Length=387, Percent_Identity=25.8397932816537, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646114, Length=387, Percent_Identity=25.8397932816537, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573067, Length=387, Percent_Identity=25.8397932816537, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28573065, Length=387, Percent_Identity=25.8397932816537, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641770, Length=410, Percent_Identity=23.9024390243902, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641760, Length=410, Percent_Identity=23.9024390243902, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641768, Length=410, Percent_Identity=23.9024390243902, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641766, Length=410, Percent_Identity=23.9024390243902, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641764, Length=410, Percent_Identity=23.9024390243902, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45551451, Length=410, Percent_Identity=23.9024390243902, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=22.3958333333333, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44256; Mature: 44125

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDEFYRIKRLPPYVIAEVNAMRAAARAAGEDIIDLGMGNPDLPPPDHVIDKLCEVARK
CCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCC
PDAHGYSQSKGIPGLRRAQANYYGRRFNVDLDPESEVVVTMGSKEGLASLATAITGPGDV
CCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCCCE
VLAPNPSYPIHTFGFIIAGATIRSVPTTPDENYWRALDRAMAFTVPRPSILVVNYPSNPT
EECCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCC
AEAVDLAFYERLVAWAKENKVWVLSDLAYSELYYDGNPTPSILQVPGAKDVAIEFTSMSK
HHHHHHHHHHHHHHHHHCCCEEEEECCHHHHEEECCCCCCCEEECCCCCCEEEEEECCCC
TYSMAGWRMGFAVGNKRLIAAMTRVKSYLDYGAFTPIQAAACAALNGPQDIVEKNRQLYQ
HHHHCCEEEEHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
KRRDVMVESFGRAGWDIPSPPASMFAWAPLPPALREMGSLEFSKQLLTHAKVAVAPGVGY
HHHHHHHHHHCCCCCCCCCCCHHHEEECCCCHHHHHHCCHHHHHHHHHHHHHEECCCCCC
GEDGEGFVRIAMVENEQRIRQAARNIRKFLAMHGVNTPSIAAGGAG
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDDEFYRIKRLPPYVIAEVNAMRAAARAAGEDIIDLGMGNPDLPPPDHVIDKLCEVARK
CCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCHHHHHHHHHHHHCC
PDAHGYSQSKGIPGLRRAQANYYGRRFNVDLDPESEVVVTMGSKEGLASLATAITGPGDV
CCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHCCCCCE
VLAPNPSYPIHTFGFIIAGATIRSVPTTPDENYWRALDRAMAFTVPRPSILVVNYPSNPT
EECCCCCCCHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHEEECCCCCEEEEECCCCCC
AEAVDLAFYERLVAWAKENKVWVLSDLAYSELYYDGNPTPSILQVPGAKDVAIEFTSMSK
HHHHHHHHHHHHHHHHHCCCEEEEECCHHHHEEECCCCCCCEEECCCCCCEEEEEECCCC
TYSMAGWRMGFAVGNKRLIAAMTRVKSYLDYGAFTPIQAAACAALNGPQDIVEKNRQLYQ
HHHHCCEEEEHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
KRRDVMVESFGRAGWDIPSPPASMFAWAPLPPALREMGSLEFSKQLLTHAKVAVAPGVGY
HHHHHHHHHHCCCCCCCCCCCHHHEEECCCCHHHHHHCCHHHHHHHHHHHHHEECCCCCC
GEDGEGFVRIAMVENEQRIRQAARNIRKFLAMHGVNTPSIAAGGAG
CCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]